Affinity Data by PubMed id=26099538

PubMed code 26099538

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
p2X7 purinoceptor (Canis lupus familiaris)	BDBM50087267 ((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of dog P2X7 receptor				Bioorg Med Chem Lett 25: 3164-7 (2015) Article DOI: 10.1016/j.bmcl.2015.06.001 BindingDB Entry DOI: 10.7270/Q22N5427
University of Leeds Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50404070 (CHEMBL338117) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor				Bioorg Med Chem Lett 25: 3164-7 (2015) Article DOI: 10.1016/j.bmcl.2015.06.001 BindingDB Entry DOI: 10.7270/Q22N5427
University of Leeds Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50087267 ((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor				Bioorg Med Chem Lett 25: 3164-7 (2015) Article DOI: 10.1016/j.bmcl.2015.06.001 BindingDB Entry DOI: 10.7270/Q22N5427
University of Leeds Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor (Cavia porcellus)	BDBM50087267 ((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of guinea pig P2X7 receptor				Bioorg Med Chem Lett 25: 3164-7 (2015) Article DOI: 10.1016/j.bmcl.2015.06.001 BindingDB Entry DOI: 10.7270/Q22N5427
University of Leeds Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50045333 (CHEBI:90705 \| SB-203580) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor				Bioorg Med Chem Lett 25: 3164-7 (2015) Article DOI: 10.1016/j.bmcl.2015.06.001 BindingDB Entry DOI: 10.7270/Q22N5427
University of Leeds Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50045333 (CHEBI:90705 \| SB-203580) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of rat P2X7 receptor				Bioorg Med Chem Lett 25: 3164-7 (2015) Article DOI: 10.1016/j.bmcl.2015.06.001 BindingDB Entry DOI: 10.7270/Q22N5427
University of Leeds Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50087267 ((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of rat P2X7 receptor				Bioorg Med Chem Lett 25: 3164-7 (2015) Article DOI: 10.1016/j.bmcl.2015.06.001 BindingDB Entry DOI: 10.7270/Q22N5427
University of Leeds Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50404070 (CHEMBL338117) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of rat P2X7 receptor				Bioorg Med Chem Lett 25: 3164-7 (2015) Article DOI: 10.1016/j.bmcl.2015.06.001 BindingDB Entry DOI: 10.7270/Q22N5427
University of Leeds Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%