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PubMed code 26151231

Compile data set for download or QSAR
Found 154 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095892
PNG
(CHEMBL3590290)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccc(C)cc12
Show InChI InChI=1S/C22H30N2O2/c1-3-4-8-13-24-20-14-16(2)11-12-18(20)21(25)19(22(24)26)15-23-17-9-6-5-7-10-17/h11-12,14-15,17,23H,3-10,13H2,1-2H3/b19-15+
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n/an/a 9n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 14n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095902
PNG
(CHEMBL3590298)
Show SMILES CCCCCN1C(=O)\C(=C\NC23CC4CC(CC(C4)C2)C3)C(=O)c2cc(OC)cc(C)c12 |TLB:18:13:20:17.19.16,18:17:20:12.13.14,THB:16:15:12:18.17.19,16:17:12:20.14.15|
Show InChI InChI=1S/C18H24N6O4/c1-3-5-6-7-8-10-22-15(19)11-16(23-10)24(9-21-11)18-13(26)12(25)14(28-18)17(27)20-4-2/h9,12-14,18,25-26H,3-6H2,1-2H3,(H,20,27)(H2,19,22,23)/t12-,13+,14+,18?/m1/s1
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n/an/a 45n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095900
PNG
(CHEMBL3590296)
Show SMILES CCCCCN1C(=O)\C(=C\NC23CC4CC(CC(C4)C2)C3)C(=O)c2cc(OC)ccc12 |TLB:18:13:20:17.19.16,18:17:20:12.13.14,THB:16:15:12:18.17.19,16:17:12:20.14.15|
Show InChI InChI=1S/C18H20N8O4/c1-2-21-17(29)14-12(27)13(28)18(30-14)26-9-22-11-15(19)23-10(24-16(11)26)4-3-6-25-7-5-20-8-25/h5,7-9,12-14,18,27-28H,2,6H2,1H3,(H,21,29)(H2,19,23,24)/t12-,13+,14+,18?/m1/s1
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n/an/a 82n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095897
PNG
(CHEMBL3590293)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)cc(C)c12
Show InChI InChI=1S/C19H23N5O6/c1-28-11-4-2-10(3-5-11)6-7-29-19-22-16(20)13-17(23-19)24(9-21-13)18-15(27)14(26)12(8-25)30-18/h2-5,9,12,14-15,18,25-27H,6-8H2,1H3,(H2,20,22,23)/t12-,14+,15+,18?/m1/s1
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n/an/a 93n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095895
PNG
(CHEMBL3590291)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccc(OC)cc12
Show InChI InChI=1S/C17H19N5O5/c18-14-11-15(21-17(20-14)26-7-9-4-2-1-3-5-9)22(8-19-11)16-13(25)12(24)10(6-23)27-16/h1-5,8,10,12-13,16,23-25H,6-7H2,(H2,18,20,21)/t10-,12+,13+,16?/m1/s1
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n/an/a 194n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095903
PNG
(CHEMBL2096743)
Show SMILES CCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(N)cc3)c(=O)[nH]c12
Show InChI InChI=1S/C16H25N5O4/c1-2-3-4-5-6-10-19-14(17)11-15(20-10)21(8-18-11)16-13(24)12(23)9(7-22)25-16/h8-9,12-13,16,22-24H,2-7H2,1H3,(H2,17,19,20)/t9-,12+,13+,16?/m1/s1
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n/an/a 545n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095901
PNG
(CHEMBL3590297)
Show SMILES CCCCCN1C(=O)\C(=C\NC23CC4CC(CC(C4)C2)C3)C(=O)c2cc(Cl)ccc12 |TLB:18:13:20:17.19.16,18:17:20:12.13.14,THB:16:15:12:18.17.19,16:17:12:20.14.15|
Show InChI InChI=1S/C18H20ClN5O5/c19-10-4-2-1-3-9(10)5-6-28-18-22-15(20)12-16(23-18)24(8-21-12)17-14(27)13(26)11(7-25)29-17/h1-4,8,11,13-14,17,25-27H,5-7H2,(H2,20,22,23)/t11-,13+,14+,17?/m1/s1
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n/an/a 957n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095898
PNG
(CHEMBL3590294)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(Cl)cc(C)c12
Show InChI InChI=1S/C13H19N5O5/c1-2-3-22-13-16-10(14)7-11(17-13)18(5-15-7)12-9(21)8(20)6(4-19)23-12/h5-6,8-9,12,19-21H,2-4H2,1H3,(H2,14,16,17)/t6-,8+,9+,12?/m1/s1
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n/an/a 1.48E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095886
PNG
(CHEMBL3590646)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(Cl)ccc12
Show InChI InChI=1S/C21H27ClN2O2/c1-2-3-7-12-24-19-11-10-15(22)13-17(19)20(25)18(21(24)26)14-23-16-8-5-4-6-9-16/h10-11,13-14,16,23H,2-9,12H2,1H3/b18-14+
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n/an/a 1.51E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095881
PNG
(CHEMBL3590641)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)ccc12
Show InChI InChI=1S/C22H30N2O3/c1-3-4-8-13-24-20-12-11-17(27-2)14-18(20)21(25)19(22(24)26)15-23-16-9-6-5-7-10-16/h11-12,14-16,23H,3-10,13H2,1-2H3/b19-15+
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n/an/a 1.65E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095887
PNG
(CHEMBL3590647)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(Br)ccc12
Show InChI InChI=1S/C21H27BrN2O2/c1-2-3-7-12-24-19-11-10-15(22)13-17(19)20(25)18(21(24)26)14-23-16-8-5-4-6-9-16/h10-11,13-14,16,23H,2-9,12H2,1H3/b18-14+
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n/an/a 1.68E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095880
PNG
(CHEMBL3590640)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)ccc12
Show InChI InChI=1S/C21H28N2O3/c1-3-4-12-23-19-11-10-16(26-2)13-17(19)20(24)18(21(23)25)14-22-15-8-6-5-7-9-15/h10-11,13-15,22H,3-9,12H2,1-2H3/b18-14+
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n/an/a 4.19E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 9.10E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095898
PNG
(CHEMBL3590294)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(Cl)cc(C)c12
Show InChI InChI=1S/C13H19N5O5/c1-2-3-22-13-16-10(14)7-11(17-13)18(5-15-7)12-9(21)8(20)6(4-19)23-12/h5-6,8-9,12,19-21H,2-4H2,1H3,(H2,14,16,17)/t6-,8+,9+,12?/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095901
PNG
(CHEMBL3590297)
Show SMILES CCCCCN1C(=O)\C(=C\NC23CC4CC(CC(C4)C2)C3)C(=O)c2cc(Cl)ccc12 |TLB:18:13:20:17.19.16,18:17:20:12.13.14,THB:16:15:12:18.17.19,16:17:12:20.14.15|
Show InChI InChI=1S/C18H20ClN5O5/c19-10-4-2-1-3-9(10)5-6-28-18-22-15(20)12-16(23-18)24(8-21-12)17-14(27)13(26)11(7-25)29-17/h1-4,8,11,13-14,17,25-27H,5-7H2,(H2,20,22,23)/t11-,13+,14+,17?/m1/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095882
PNG
(CHEMBL3590642)
Show SMILES CCCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)ccc12
Show InChI InChI=1S/C23H32N2O3/c1-3-4-5-9-14-25-21-13-12-18(28-2)15-19(21)22(26)20(23(25)27)16-24-17-10-7-6-8-11-17/h12-13,15-17,24H,3-11,14H2,1-2H3/b20-16+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095884
PNG
(CHEMBL3590644)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(ccc12)C(C)(C)C
Show InChI InChI=1S/C25H36N2O2/c1-5-6-10-15-27-22-14-13-18(25(2,3)4)16-20(22)23(28)21(24(27)29)17-26-19-11-8-7-9-12-19/h13-14,16-17,19,26H,5-12,15H2,1-4H3/b21-17+
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095899
PNG
(CHEMBL3590295)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)cc(OC)c12
Show InChI InChI=1S/C14H21N5O4/c1-2-3-4-8-17-12(15)9-13(18-8)19(6-16-9)14-11(22)10(21)7(5-20)23-14/h6-7,10-11,14,20-22H,2-5H2,1H3,(H2,15,17,18)/t7-,10+,11+,14?/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095881
PNG
(CHEMBL3590641)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)ccc12
Show InChI InChI=1S/C22H30N2O3/c1-3-4-8-13-24-20-12-11-17(27-2)14-18(20)21(25)19(22(24)26)15-23-16-9-6-5-7-10-16/h11-12,14-16,23H,3-10,13H2,1-2H3/b19-15+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095882
PNG
(CHEMBL3590642)
Show SMILES CCCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)ccc12
Show InChI InChI=1S/C23H32N2O3/c1-3-4-5-9-14-25-21-13-12-18(28-2)15-19(21)22(26)20(23(25)27)16-24-17-10-7-6-8-11-17/h12-13,15-17,24H,3-11,14H2,1-2H3/b20-16+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095887
PNG
(CHEMBL3590647)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(Br)ccc12
Show InChI InChI=1S/C21H27BrN2O2/c1-2-3-7-12-24-19-11-10-15(22)13-17(19)20(25)18(21(24)26)14-23-16-8-5-4-6-9-16/h10-11,13-14,16,23H,2-9,12H2,1H3/b18-14+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095895
PNG
(CHEMBL3590291)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccc(OC)cc12
Show InChI InChI=1S/C17H19N5O5/c18-14-11-15(21-17(20-14)26-7-9-4-2-1-3-5-9)22(8-19-11)16-13(25)12(24)10(6-23)27-16/h1-5,8,10,12-13,16,23-25H,6-7H2,(H2,18,20,21)/t10-,12+,13+,16?/m1/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095899
PNG
(CHEMBL3590295)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)cc(OC)c12
Show InChI InChI=1S/C14H21N5O4/c1-2-3-4-8-17-12(15)9-13(18-8)19(6-16-9)14-11(22)10(21)7(5-20)23-14/h6-7,10-11,14,20-22H,2-5H2,1H3,(H2,15,17,18)/t7-,10+,11+,14?/m1/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095883
PNG
(CHEMBL3590643)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(C)ccc12
Show InChI InChI=1S/C22H30N2O2/c1-3-4-8-13-24-20-12-11-16(2)14-18(20)21(25)19(22(24)26)15-23-17-9-6-5-7-10-17/h11-12,14-15,17,23H,3-10,13H2,1-2H3/b19-15+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095897
PNG
(CHEMBL3590293)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)cc(C)c12
Show InChI InChI=1S/C19H23N5O6/c1-28-11-4-2-10(3-5-11)6-7-29-19-22-16(20)13-17(23-19)24(9-21-13)18-15(27)14(26)12(8-25)30-18/h2-5,9,12,14-15,18,25-27H,6-8H2,1H3,(H2,20,22,23)/t12-,14+,15+,18?/m1/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095903
PNG
(CHEMBL2096743)
Show SMILES CCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(N)cc3)c(=O)[nH]c12
Show InChI InChI=1S/C16H25N5O4/c1-2-3-4-5-6-10-19-14(17)11-15(20-10)21(8-18-11)16-13(24)12(23)9(7-22)25-16/h8-9,12-13,16,22-24H,2-7H2,1H3,(H2,17,19,20)/t9-,12+,13+,16?/m1/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095885
PNG
(CHEMBL3590645)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC(F)(F)F)ccc12
Show InChI InChI=1S/C22H27F3N2O3/c1-2-3-7-12-27-19-11-10-16(30-22(23,24)25)13-17(19)20(28)18(21(27)29)14-26-15-8-5-4-6-9-15/h10-11,13-15,26H,2-9,12H2,1H3/b18-14+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095880
PNG
(CHEMBL3590640)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC)ccc12
Show InChI InChI=1S/C21H28N2O3/c1-3-4-12-23-19-11-10-16(26-2)13-17(19)20(24)18(21(23)25)14-22-15-8-6-5-7-9-15/h10-11,13-15,22H,3-9,12H2,1-2H3/b18-14+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095902
PNG
(CHEMBL3590298)
Show SMILES CCCCCN1C(=O)\C(=C\NC23CC4CC(CC(C4)C2)C3)C(=O)c2cc(OC)cc(C)c12 |TLB:18:13:20:17.19.16,18:17:20:12.13.14,THB:16:15:12:18.17.19,16:17:12:20.14.15|
Show InChI InChI=1S/C18H24N6O4/c1-3-5-6-7-8-10-22-15(19)11-16(23-10)24(9-21-11)18-13(26)12(25)14(28-18)17(27)20-4-2/h9,12-14,18,25-26H,3-6H2,1-2H3,(H,20,27)(H2,19,22,23)/t12-,13+,14+,18?/m1/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095884
PNG
(CHEMBL3590644)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(ccc12)C(C)(C)C
Show InChI InChI=1S/C25H36N2O2/c1-5-6-10-15-27-22-14-13-18(25(2,3)4)16-20(22)23(28)21(24(27)29)17-26-19-11-8-7-9-12-19/h13-14,16-17,19,26H,5-12,15H2,1-4H3/b21-17+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095883
PNG
(CHEMBL3590643)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(C)ccc12
Show InChI InChI=1S/C22H30N2O2/c1-3-4-8-13-24-20-12-11-16(2)14-18(20)21(25)19(22(24)26)15-23-17-9-6-5-7-10-17/h11-12,14-15,17,23H,3-10,13H2,1-2H3/b19-15+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095885
PNG
(CHEMBL3590645)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(OC(F)(F)F)ccc12
Show InChI InChI=1S/C22H27F3N2O3/c1-2-3-7-12-27-19-11-10-16(30-22(23,24)25)13-17(19)20(28)18(21(27)29)14-26-15-8-5-4-6-9-15/h10-11,13-15,26H,2-9,12H2,1H3/b18-14+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095900
PNG
(CHEMBL3590296)
Show SMILES CCCCCN1C(=O)\C(=C\NC23CC4CC(CC(C4)C2)C3)C(=O)c2cc(OC)ccc12 |TLB:18:13:20:17.19.16,18:17:20:12.13.14,THB:16:15:12:18.17.19,16:17:12:20.14.15|
Show InChI InChI=1S/C18H20N8O4/c1-2-21-17(29)14-12(27)13(28)18(30-14)26-9-22-11-15(19)23-10(24-16(11)26)4-3-6-25-7-5-20-8-25/h5,7-9,12-14,18,27-28H,2,6H2,1H3,(H,21,29)(H2,19,23,24)/t12-,13+,14+,18?/m1/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095888
PNG
(CHEMBL3590648)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(ccc12)C(F)(F)F
Show InChI InChI=1S/C22H27F3N2O2/c1-2-3-7-12-27-19-11-10-15(22(23,24)25)13-17(19)20(28)18(21(27)29)14-26-16-8-5-4-6-9-16/h10-11,13-14,16,26H,2-9,12H2,1H3/b18-14+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095888
PNG
(CHEMBL3590648)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(ccc12)C(F)(F)F
Show InChI InChI=1S/C22H27F3N2O2/c1-2-3-7-12-27-19-11-10-15(22(23,24)25)13-17(19)20(28)18(21(27)29)14-26-16-8-5-4-6-9-16/h10-11,13-14,16,26H,2-9,12H2,1H3/b18-14+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095896
PNG
(CHEMBL3590292)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccc(Cl)cc12
Show InChI InChI=1S/C20H28N6O6/c1-2-22-18(29)15-13(27)14(28)19(32-15)26-8-23-12-16(21)24-11(25-17(12)26)7-9-3-5-10(6-4-9)20(30)31/h8-10,13-15,19,27-28H,2-7H2,1H3,(H,22,29)(H,30,31)(H2,21,24,25)/t9?,10?,13-,14+,15+,19?/m1/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095892
PNG
(CHEMBL3590290)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccc(C)cc12
Show InChI InChI=1S/C22H30N2O2/c1-3-4-8-13-24-20-14-16(2)11-12-18(20)21(25)19(22(24)26)15-23-17-9-6-5-7-10-17/h11-12,14-15,17,23H,3-10,13H2,1-2H3/b19-15+
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Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095886
PNG
(CHEMBL3590646)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cc(Cl)ccc12
Show InChI InChI=1S/C21H27ClN2O2/c1-2-3-7-12-24-19-11-10-15(22)13-17(19)20(25)18(21(24)26)14-23-16-8-5-4-6-9-16/h10-11,13-14,16,23H,2-9,12H2,1H3/b18-14+
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095896
PNG
(CHEMBL3590292)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccc(Cl)cc12
Show InChI InChI=1S/C20H28N6O6/c1-2-22-18(29)15-13(27)14(28)19(32-15)26-8-23-12-16(21)24-11(25-17(12)26)7-9-3-5-10(6-4-9)20(30)31/h8-10,13-15,19,27-28H,2-7H2,1H3,(H,22,29)(H,30,31)(H2,21,24,25)/t9?,10?,13-,14+,15+,19?/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Antagonist activity against CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as inhibition of CP55940-induced increase in intracel...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095861
PNG
(CHEMBL3590613)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(OC)c12
Show InChI InChI=1S/C18H28N6O4/c1-2-3-4-5-6-7-8-20-17(27)14-12(25)13(26)18(28-14)24-10-23-11-15(19)21-9-22-16(11)24/h9-10,12-14,18,25-26H,2-8H2,1H3,(H,20,27)(H2,19,21,22)/t12?,13?,14-,18+/m0/s1
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n/an/an/an/a 1.42E+3n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095842
PNG
(CHEMBL3590605)
Show SMILES CCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C11H14N6O5/c1-21-16-10(20)7-5(18)6(19)11(22-7)17-3-15-4-8(12)13-2-14-9(4)17/h2-3,5-7,11,18-19H,1H3,(H,16,20)(H2,12,13,14)/t5?,6?,7-,11+/m0/s1
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n/an/an/an/a 1.79E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095867
PNG
(CHEMBL3590639)
Show SMILES Cc1cccc2C(=O)\C(=C/NC(C)(C)C)C(=O)N(CCC=C)c12
Show InChI InChI=1S/C14H20N6O4/c1-14(2,3)19-12(23)9-7(21)8(22)13(24-9)20-5-18-6-10(15)16-4-17-11(6)20/h4-5,7-9,13,21-22H,1-3H3,(H,19,23)(H2,15,16,17)/t7?,8?,9-,13+/m0/s1
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n/an/an/an/a 75n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095868
PNG
(CHEMBL3588878)
Show SMILES Cc1cccc2C(=O)\C(=C/NC(C)(C)C)C(=O)N(CC3CC3)c12
Show InChI InChI=1S/C19H30N6O4/c1-2-3-4-5-6-7-8-9-21-18(28)15-13(26)14(27)19(29-15)25-11-24-12-16(20)22-10-23-17(12)25/h10-11,13-15,19,26-27H,2-9H2,1H3,(H,21,28)(H2,20,22,23)/t13?,14?,15-,19+/m0/s1
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n/an/an/an/a 104n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095872
PNG
(CHEMBL3590635)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)CCC)C(=O)c2cccc(C)c12
Show InChI InChI=1/C20H28N2O2/c1-5-7-12-22-18-14(3)10-8-11-16(18)19(23)17(20(22)24)13-21-15(4)9-6-2/h8,10-11,13,15,21H,5-7,9,12H2,1-4H3/b17-13+
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n/an/an/an/a 116n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095875
PNG
(CHEMBL3590632)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H26N2O2/c1-6-7-11-21-16-13(2)9-8-10-14(16)17(22)15(18(21)23)12-20-19(3,4)5/h8-10,12,20H,6-7,11H2,1-5H3/b15-12+
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n/an/an/an/a 20n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095849
PNG
(CHEMBL3590625)
Show SMILES CCCCN1C(=O)\C(=C\NN2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H26N6O4/c21-17-13-18(23-6-22-17)26(7-24-13)20-15(28)14(27)16(30-20)19(29)25-12-10-2-8-1-9(4-10)5-11(12)3-8/h6-12,14-16,20,27-28H,1-5H2,(H,25,29)(H2,21,22,23)/t8?,9?,10?,11?,12?,14?,15?,16-,20+/m0/s1
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n/an/an/an/a 993n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095870
PNG
(CHEMBL3590637)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)(C)CC)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H28N2O2/c1-6-8-12-22-17-14(3)10-9-11-15(17)18(23)16(19(22)24)13-21-20(4,5)7-2/h9-11,13,21H,6-8,12H2,1-5H3/b16-13+
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n/an/an/an/a 2.02E+3n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095874
PNG
(CHEMBL3590633)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)(C)CO)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H26N2O3/c1-5-6-10-21-16-13(2)8-7-9-14(16)17(23)15(18(21)24)11-20-19(3,4)12-22/h7-9,11,20,22H,5-6,10,12H2,1-4H3/b15-11+
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n/an/an/an/a 557n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095847
PNG
(CHEMBL3590627)
Show SMILES CCCCN1C(=O)\C(=C\N[C@H]2CC[C@H](O)CC2)C(=O)c2cccc(C)c12 |r,wU:10.9,wD:13.13,(3.74,-6,;2.67,-5.39,;2.67,-3.85,;1.33,-3.08,;1.33,-1.54,;2.66,-.77,;3.73,-1.38,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.33,5.4,;6.66,6.17,;7.99,5.4,;9.06,6.01,;7.99,3.86,;6.66,3.09,;1.33,1.54,;1.33,2.77,;,.77,;-1.33,1.54,;-2.68,.77,;-2.68,-.77,;-1.33,-1.54,;-1.33,-2.77,;,-.77,)|
Show InChI InChI=1S/C12H16N6O5/c1-2-22-17-11(21)8-6(19)7(20)12(23-8)18-4-16-5-9(13)14-3-15-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,17,21)(H2,13,14,15)/t6?,7?,8-,12+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095849
PNG
(CHEMBL3590625)
Show SMILES CCCCN1C(=O)\C(=C\NN2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H26N6O4/c21-17-13-18(23-6-22-17)26(7-24-13)20-15(28)14(27)16(30-20)19(29)25-12-10-2-8-1-9(4-10)5-11(12)3-8/h6-12,14-16,20,27-28H,1-5H2,(H,25,29)(H2,21,22,23)/t8?,9?,10?,11?,12?,14?,15?,16-,20+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095859
PNG
(CHEMBL3590615)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(Cl)c12
Show InChI InChI=1S/C13H16N6O4/c14-10-6-11(16-3-15-10)19(4-17-6)13-8(21)7(20)9(23-13)12(22)18-5-1-2-5/h3-5,7-9,13,20-21H,1-2H2,(H,18,22)(H2,14,15,16)/t7?,8?,9-,13+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095861
PNG
(CHEMBL3590613)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(OC)c12
Show InChI InChI=1S/C18H28N6O4/c1-2-3-4-5-6-7-8-20-17(27)14-12(25)13(26)18(28-14)24-10-23-11-15(19)21-9-22-16(11)24/h9-10,12-14,18,25-26H,2-8H2,1H3,(H,20,27)(H2,19,21,22)/t12?,13?,14-,18+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095865
PNG
(CHEMBL3590609)
Show SMILES Cc1cccc2C(=O)\C(=C/NC3CCCCC3)C(=O)N(CC3CC3)c12
Show InChI InChI=1S/C17H18N6O4/c18-14-10-15(21-7-20-14)23(8-22-10)17-12(25)11(24)13(27-17)16(26)19-6-9-4-2-1-3-5-9/h1-5,7-8,11-13,17,24-25H,6H2,(H,19,26)(H2,18,20,21)/t11?,12?,13-,17+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095841
PNG
(CHEMBL3590606)
Show SMILES CCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C17H24N6O4/c1-8-2-4-9(5-3-8)22-16(26)13-11(24)12(25)17(27-13)23-7-21-10-14(18)19-6-20-15(10)23/h6-9,11-13,17,24-25H,2-5H2,1H3,(H,22,26)(H2,18,19,20)/t8-,9?,11?,12?,13-,17+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095848
PNG
(CHEMBL3590626)
Show SMILES CCCCN1C(=O)\C(=C\NN2CCOCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C17H24N6O4/c18-14-10-15(20-7-19-14)23(8-21-10)17-12(25)11(24)13(27-17)16(26)22-9-5-3-1-2-4-6-9/h7-9,11-13,17,24-25H,1-6H2,(H,22,26)(H2,18,19,20)/t11?,12?,13-,17+/m0/s1
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n/an/an/an/a 477n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095850
PNG
(CHEMBL3590624)
Show SMILES CCCCN1C(=O)\C(=C\NCC2CCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C12H13N5O4/c1-2-5(18)9-7(19)8(20)12(21-9)17-4-16-6-10(13)14-3-15-11(6)17/h1,3-5,7-9,12,18-20H,(H2,13,14,15)/t5?,7?,8?,9-,12-/m1/s1
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n/an/an/an/a 220n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095851
PNG
(CHEMBL3590623)
Show SMILES CCCCN1C(=O)\C(=C\NCC2CC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C16H24N6O4/c1-2-3-4-5-6-18-15(25)12-10(23)11(24)16(26-12)22-8-21-9-13(17)19-7-20-14(9)22/h7-8,10-12,16,23-24H,2-6H2,1H3,(H,18,25)(H2,17,19,20)/t10?,11?,12-,16+/m0/s1
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n/an/an/an/a 127n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095854
PNG
(CHEMBL3590620)
Show SMILES CCCCN1C(=O)\C(=C\Nc2ccccn2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C17H26N6O4/c1-2-3-4-5-6-7-19-16(26)13-11(24)12(25)17(27-13)23-9-22-10-14(18)20-8-21-15(10)23/h8-9,11-13,17,24-25H,2-7H2,1H3,(H,19,26)(H2,18,20,21)/t11?,12?,13-,17+/m0/s1
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n/an/an/an/a 2.39E+3n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095867
PNG
(CHEMBL3590639)
Show SMILES Cc1cccc2C(=O)\C(=C/NC(C)(C)C)C(=O)N(CCC=C)c12
Show InChI InChI=1S/C14H20N6O4/c1-14(2,3)19-12(23)9-7(21)8(22)13(24-9)20-5-18-6-10(15)16-4-17-11(6)20/h4-5,7-9,13,21-22H,1-3H3,(H,19,23)(H2,15,16,17)/t7?,8?,9-,13+/m0/s1
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n/an/an/an/a 75n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095874
PNG
(CHEMBL3590633)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)(C)CO)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H26N2O3/c1-5-6-10-21-16-13(2)8-7-9-14(16)17(23)15(18(21)24)11-20-19(3,4)12-22/h7-9,11,20,22H,5-6,10,12H2,1-4H3/b15-11+
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n/an/an/an/a 41n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095876
PNG
(CHEMBL3590631)
Show SMILES CCCCN1C(=O)\C(=C\NCC(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H26N2O2/c1-5-6-10-21-17-14(4)8-7-9-15(17)18(22)16(19(21)23)12-20-11-13(2)3/h7-9,12-13,20H,5-6,10-11H2,1-4H3/b16-12+
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n/an/an/an/a 44n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095870
PNG
(CHEMBL3590637)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)(C)CC)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H28N2O2/c1-6-8-12-22-17-14(3)10-9-11-15(17)18(23)16(19(22)24)13-21-20(4,5)7-2/h9-11,13,21H,6-8,12H2,1-5H3/b16-13+
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n/an/an/an/a 75n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095868
PNG
(CHEMBL3588878)
Show SMILES Cc1cccc2C(=O)\C(=C/NC(C)(C)C)C(=O)N(CC3CC3)c12
Show InChI InChI=1S/C19H30N6O4/c1-2-3-4-5-6-7-8-9-21-18(28)15-13(26)14(27)19(29-15)25-11-24-12-16(20)22-10-23-17(12)25/h10-11,13-15,19,26-27H,2-9H2,1H3,(H,21,28)(H2,20,22,23)/t13?,14?,15-,19+/m0/s1
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n/an/an/an/a 104n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095842
PNG
(CHEMBL3590605)
Show SMILES CCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C11H14N6O5/c1-21-16-10(20)7-5(18)6(19)11(22-7)17-3-15-4-8(12)13-2-14-9(4)17/h2-3,5-7,11,18-19H,1H3,(H,16,20)(H2,12,13,14)/t5?,6?,7-,11+/m0/s1
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n/an/an/an/a 1.79E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095841
PNG
(CHEMBL3590606)
Show SMILES CCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C17H24N6O4/c1-8-2-4-9(5-3-8)22-16(26)13-11(24)12(25)17(27-13)23-7-21-10-14(18)19-6-20-15(10)23/h6-9,11-13,17,24-25H,2-5H2,1H3,(H,22,26)(H2,18,19,20)/t8-,9?,11?,12?,13-,17+/m0/s1
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n/an/an/an/a 497n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095865
PNG
(CHEMBL3590609)
Show SMILES Cc1cccc2C(=O)\C(=C/NC3CCCCC3)C(=O)N(CC3CC3)c12
Show InChI InChI=1S/C17H18N6O4/c18-14-10-15(21-7-20-14)23(8-22-10)17-12(25)11(24)13(27-17)16(26)19-6-9-4-2-1-3-5-9/h1-5,7-8,11-13,17,24-25H,6H2,(H,19,26)(H2,18,20,21)/t11?,12?,13-,17+/m0/s1
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n/an/an/an/a 670n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095863
PNG
(CHEMBL3590611)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(CC)c12
Show InChI InChI=1S/C17H22N6O4/c18-14-10-15(20-5-19-14)23(6-21-10)17-12(25)11(24)13(27-17)16(26)22-9-4-7-1-2-8(9)3-7/h5-9,11-13,17,24-25H,1-4H2,(H,22,26)(H2,18,19,20)/t7?,8?,9?,11?,12?,13-,17+/m0/s1
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n/an/an/an/a 800n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095876
PNG
(CHEMBL3590631)
Show SMILES CCCCN1C(=O)\C(=C\NCC(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H26N2O2/c1-5-6-10-21-17-14(4)8-7-9-15(17)18(22)16(19(21)23)12-20-11-13(2)3/h7-9,12-13,20H,5-6,10-11H2,1-4H3/b16-12+
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n/an/an/an/a 44n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095873
PNG
(CHEMBL3590634)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)C(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1/C20H28N2O2/c1-6-7-11-22-18-14(4)9-8-10-16(18)19(23)17(20(22)24)12-21-15(5)13(2)3/h8-10,12-13,15,21H,6-7,11H2,1-5H3/b17-12+
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n/an/an/an/a 83n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095877
PNG
(CHEMBL3590630)
Show SMILES CCCCN\C=C1\C(=O)N(CCCC)c2c(C)cccc2C1=O
Show InChI InChI=1S/C19H26N2O2/c1-4-6-11-20-13-16-18(22)15-10-8-9-14(3)17(15)21(19(16)23)12-7-5-2/h8-10,13,20H,4-7,11-12H2,1-3H3/b16-13+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095879
PNG
(CHEMBL3590628)
Show SMILES CCCCN1C(=O)\C(=C\NCCC)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C18H24N2O2/c1-4-6-11-20-16-13(3)8-7-9-14(16)17(21)15(18(20)22)12-19-10-5-2/h7-9,12,19H,4-6,10-11H2,1-3H3/b15-12+
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095863
PNG
(CHEMBL3590611)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(CC)c12
Show InChI InChI=1S/C17H22N6O4/c18-14-10-15(20-5-19-14)23(6-21-10)17-12(25)11(24)13(27-17)16(26)22-9-4-7-1-2-8(9)3-7/h5-9,11-13,17,24-25H,1-4H2,(H,22,26)(H2,18,19,20)/t7?,8?,9?,11?,12?,13-,17+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095844
PNG
(CHEMBL3590603)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2c(C)cccc12
Show InChI InChI=1S/C20H32N6O4/c1-2-3-4-5-6-7-8-9-10-22-19(29)16-14(27)15(28)20(30-16)26-12-25-13-17(21)23-11-24-18(13)26/h11-12,14-16,20,27-28H,2-10H2,1H3,(H,22,29)(H2,21,23,24)/t14?,15?,16-,20+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095845
PNG
(CHEMBL3590602)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccccc12
Show InChI InChI=1S/C15H22N6O4/c1-2-3-4-5-17-14(24)11-9(22)10(23)15(25-11)21-7-20-8-12(16)18-6-19-13(8)21/h6-7,9-11,15,22-23H,2-5H2,1H3,(H,17,24)(H2,16,18,19)/t9?,10?,11-,15+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095853
PNG
(CHEMBL3590621)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H26N2O2/c1-3-4-12-22-18-14(2)8-7-11-16(18)19(23)17(20(22)24)13-21-15-9-5-6-10-15/h7-8,11,13,15,21H,3-6,9-10,12H2,1-2H3/b17-13+
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n/an/an/an/a 58n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095865
PNG
(CHEMBL3590609)
Show SMILES Cc1cccc2C(=O)\C(=C/NC3CCCCC3)C(=O)N(CC3CC3)c12
Show InChI InChI=1S/C17H18N6O4/c18-14-10-15(21-7-20-14)23(8-22-10)17-12(25)11(24)13(27-17)16(26)19-6-9-4-2-1-3-5-9/h1-5,7-8,11-13,17,24-25H,6H2,(H,19,26)(H2,18,20,21)/t11?,12?,13-,17+/m0/s1
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n/an/an/an/a 670n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095841
PNG
(CHEMBL3590606)
Show SMILES CCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C17H24N6O4/c1-8-2-4-9(5-3-8)22-16(26)13-11(24)12(25)17(27-13)23-7-21-10-14(18)19-6-20-15(10)23/h6-9,11-13,17,24-25H,2-5H2,1H3,(H,22,26)(H2,18,19,20)/t8-,9?,11?,12?,13-,17+/m0/s1
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n/an/an/an/a 497n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095869
PNG
(CHEMBL3590638)
Show SMILES CCCN1C(=O)\C(=C\NC(C)(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H24N6O4/c20-15-11-16(22-6-21-15)25(7-23-11)18-13(27)12(26)14(29-18)17(28)24-19-3-8-1-9(4-19)10(2-8)5-19/h6-10,12-14,18,26-27H,1-5H2,(H,24,28)(H2,20,21,22)/t8?,9?,10?,12?,13?,14-,18+,19?/m0/s1
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n/an/an/an/a 36n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095840
PNG
(CHEMBL3590607)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C12H17N7O4/c13-1-2-15-11(22)8-6(20)7(21)12(23-8)19-4-18-5-9(14)16-3-17-10(5)19/h3-4,6-8,12,20-21H,1-2,13H2,(H,15,22)(H2,14,16,17)/t6?,7?,8-,12+/m0/s1
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n/an/an/an/a 93n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095852
PNG
(CHEMBL3590622)
Show SMILES CCCCN1C(=O)\C(=C\NC2CC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C18H22N2O2/c1-3-4-10-20-16-12(2)6-5-7-14(16)17(21)15(18(20)22)11-19-13-8-9-13/h5-7,11,13,19H,3-4,8-10H2,1-2H3/b15-11+
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n/an/an/an/a 504n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095868
PNG
(CHEMBL3588878)
Show SMILES Cc1cccc2C(=O)\C(=C/NC(C)(C)C)C(=O)N(CC3CC3)c12
Show InChI InChI=1S/C19H30N6O4/c1-2-3-4-5-6-7-8-9-21-18(28)15-13(26)14(27)19(29-15)25-11-24-12-16(20)22-10-23-17(12)25/h10-11,13-15,19,26-27H,2-9H2,1H3,(H,21,28)(H2,20,22,23)/t13?,14?,15-,19+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095871
PNG
(CHEMBL3590636)
Show SMILES CCCCN1C(=O)\C(=C\NC(CC)CC)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H28N2O2/c1-5-8-12-22-18-14(4)10-9-11-16(18)19(23)17(20(22)24)13-21-15(6-2)7-3/h9-11,13,15,21H,5-8,12H2,1-4H3/b17-13+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095873
PNG
(CHEMBL3590634)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)C(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1/C20H28N2O2/c1-6-7-11-22-18-14(4)9-8-10-16(18)19(23)17(20(22)24)12-21-15(5)13(2)3/h8-10,12-13,15,21H,6-7,11H2,1-5H3/b17-12+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095876
PNG
(CHEMBL3590631)
Show SMILES CCCCN1C(=O)\C(=C\NCC(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H26N2O2/c1-5-6-10-21-17-14(4)8-7-9-15(17)18(22)16(19(21)23)12-20-11-13(2)3/h7-9,12-13,20H,5-6,10-11H2,1-4H3/b16-12+
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095878
PNG
(CHEMBL3590629)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C18H24N2O2/c1-5-6-10-20-16-13(4)8-7-9-14(16)17(21)15(18(20)22)11-19-12(2)3/h7-9,11-12,19H,5-6,10H2,1-4H3/b15-11+
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095850
PNG
(CHEMBL3590624)
Show SMILES CCCCN1C(=O)\C(=C\NCC2CCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C12H13N5O4/c1-2-5(18)9-7(19)8(20)12(21-9)17-4-16-6-10(13)14-3-15-11(6)17/h1,3-5,7-9,12,18-20H,(H2,13,14,15)/t5?,7?,8?,9-,12-/m1/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50211843
PNG
(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)
Show SMILES FC(F)(F)c1nc(Nc2ccc(Cl)cc2Cl)ncc1C(=O)NCC1CCOCC1
Show InChI InChI=1S/C18H17Cl2F3N4O2/c19-11-1-2-14(13(20)7-11)26-17-25-9-12(15(27-17)18(21,22)23)16(28)24-8-10-3-5-29-6-4-10/h1-2,7,9-10H,3-6,8H2,(H,24,28)(H,25,26,27)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095843
PNG
(CHEMBL3590604)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2c(OC)cccc12
Show InChI InChI=1S/C10H12N6O5/c11-7-3-8(13-1-12-7)16(2-14-3)10-5(18)4(17)6(21-10)9(19)15-20/h1-2,4-6,10,17-18,20H,(H,15,19)(H2,11,12,13)/t4?,5?,6-,10+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095847
PNG
(CHEMBL3590627)
Show SMILES CCCCN1C(=O)\C(=C\N[C@H]2CC[C@H](O)CC2)C(=O)c2cccc(C)c12 |r,wU:10.9,wD:13.13,(3.74,-6,;2.67,-5.39,;2.67,-3.85,;1.33,-3.08,;1.33,-1.54,;2.66,-.77,;3.73,-1.38,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.33,5.4,;6.66,6.17,;7.99,5.4,;9.06,6.01,;7.99,3.86,;6.66,3.09,;1.33,1.54,;1.33,2.77,;,.77,;-1.33,1.54,;-2.68,.77,;-2.68,-.77,;-1.33,-1.54,;-1.33,-2.77,;,-.77,)|
Show InChI InChI=1S/C12H16N6O5/c1-2-22-17-11(21)8-6(19)7(20)12(23-8)18-4-16-5-9(13)14-3-15-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,17,21)(H2,13,14,15)/t6?,7?,8-,12+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095858
PNG
(CHEMBL3590616)
Show SMILES CCCCN1C(=O)\C(=C\NC23CC4CC(CC(C4)C2)C3)C(=O)c2cccc(C)c12 |TLB:17:12:19:16.18.15,17:16:19:11.12.13,THB:15:14:11:17.16.18,15:16:11:19.13.14|
Show InChI InChI=1S/C25H32N2O2/c1-3-4-8-27-22-16(2)6-5-7-20(22)23(28)21(24(27)29)15-26-25-12-17-9-18(13-25)11-19(10-17)14-25/h5-7,15,17-19,26H,3-4,8-14H2,1-2H3/b21-15+
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n/an/an/an/a 317n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095859
PNG
(CHEMBL3590615)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(Cl)c12
Show InChI InChI=1S/C13H16N6O4/c14-10-6-11(16-3-15-10)19(4-17-6)13-8(21)7(20)9(23-13)12(22)18-5-1-2-5/h3-5,7-9,13,20-21H,1-2H2,(H,18,22)(H2,14,15,16)/t7?,8?,9-,13+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095860
PNG
(CHEMBL3590614)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(OC)c12
Show InChI InChI=1S/C17H24N6O4/c1-8-4-2-3-5-9(8)22-16(26)13-11(24)12(25)17(27-13)23-7-21-10-14(18)19-6-20-15(10)23/h6-9,11-13,17,24-25H,2-5H2,1H3,(H,22,26)(H2,18,19,20)/t8?,9?,11?,12?,13-,17+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095864
PNG
(CHEMBL3590610)
Show SMILES Cc1cccc2C(=O)\C(=C/NC3CCCCC3)C(=O)N(CCC=C)c12
Show InChI InChI=1S/C11H14N6O4/c1-13-10(20)7-5(18)6(19)11(21-7)17-3-16-4-8(12)14-2-15-9(4)17/h2-3,5-7,11,18-19H,1H3,(H,13,20)(H2,12,14,15)/t5?,6?,7-,11+/m0/s1
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n/an/an/an/a 749n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095840
PNG
(CHEMBL3590607)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C12H17N7O4/c13-1-2-15-11(22)8-6(20)7(21)12(23-8)19-4-18-5-9(14)16-3-17-10(5)19/h3-4,6-8,12,20-21H,1-2,13H2,(H,15,22)(H2,14,16,17)/t6?,7?,8-,12+/m0/s1
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n/an/an/an/a 93n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095873
PNG
(CHEMBL3590634)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)C(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1/C20H28N2O2/c1-6-7-11-22-18-14(4)9-8-10-16(18)19(23)17(20(22)24)12-21-15(5)13(2)3/h8-10,12-13,15,21H,6-7,11H2,1-5H3/b17-12+
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n/an/an/an/a 83n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095872
PNG
(CHEMBL3590635)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)CCC)C(=O)c2cccc(C)c12
Show InChI InChI=1/C20H28N2O2/c1-5-7-12-22-18-14(3)10-8-11-16(18)19(23)17(20(22)24)13-21-15(4)9-6-2/h8,10-11,13,15,21H,5-7,9,12H2,1-4H3/b17-13+
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n/an/an/an/a 116n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095871
PNG
(CHEMBL3590636)
Show SMILES CCCCN1C(=O)\C(=C\NC(CC)CC)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H28N2O2/c1-5-8-12-22-18-14(4)10-9-11-16(18)19(23)17(20(22)24)13-21-15(6-2)7-3/h9-11,13,15,21H,5-8,12H2,1-4H3/b17-13+
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n/an/an/an/a 112n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095866
PNG
(CHEMBL3590608)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H31N7O5/c1-12(28)22-8-6-4-2-3-5-7-9-23-19(31)16-14(29)15(30)20(32-16)27-11-26-13-17(21)24-10-25-18(13)27/h10-11,14-16,20,29-30H,2-9H2,1H3,(H,22,28)(H,23,31)(H2,21,24,25)/t14?,15?,16-,20+/m0/s1
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n/an/an/an/a 320n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095877
PNG
(CHEMBL3590630)
Show SMILES CCCCN\C=C1\C(=O)N(CCCC)c2c(C)cccc2C1=O
Show InChI InChI=1S/C19H26N2O2/c1-4-6-11-20-13-16-18(22)15-10-8-9-14(3)17(15)21(19(16)23)12-7-5-2/h8-10,13,20H,4-7,11-12H2,1-3H3/b16-13+
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n/an/an/an/a 91n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095875
PNG
(CHEMBL3590632)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H26N2O2/c1-6-7-11-21-16-13(2)9-8-10-14(16)17(22)15(18(21)23)12-20-19(3,4)5/h8-10,12,20H,6-7,11H2,1-5H3/b15-12+
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n/an/an/an/a 20n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095844
PNG
(CHEMBL3590603)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2c(C)cccc12
Show InChI InChI=1S/C20H32N6O4/c1-2-3-4-5-6-7-8-9-10-22-19(29)16-14(27)15(28)20(30-16)26-12-25-13-17(21)23-11-24-18(13)26/h11-12,14-16,20,27-28H,2-10H2,1H3,(H,22,29)(H2,21,23,24)/t14?,15?,16-,20+/m0/s1
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n/an/an/an/a 341n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095845
PNG
(CHEMBL3590602)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccccc12
Show InChI InChI=1S/C15H22N6O4/c1-2-3-4-5-17-14(24)11-9(22)10(23)15(25-11)21-7-20-8-12(16)18-6-19-13(8)21/h6-7,9-11,15,22-23H,2-5H2,1H3,(H,17,24)(H2,16,18,19)/t9?,10?,11-,15+/m0/s1
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n/an/an/an/a 472n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095872
PNG
(CHEMBL3590635)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)CCC)C(=O)c2cccc(C)c12
Show InChI InChI=1/C20H28N2O2/c1-5-7-12-22-18-14(3)10-8-11-16(18)19(23)17(20(22)24)13-21-15(4)9-6-2/h8,10-11,13,15,21H,5-7,9,12H2,1-4H3/b17-13+
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095848
PNG
(CHEMBL3590626)
Show SMILES CCCCN1C(=O)\C(=C\NN2CCOCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C17H24N6O4/c18-14-10-15(20-7-19-14)23(8-21-10)17-12(25)11(24)13(27-17)16(26)22-9-5-3-1-2-4-6-9/h7-9,11-13,17,24-25H,1-6H2,(H,22,26)(H2,18,19,20)/t11?,12?,13-,17+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095857
PNG
(CHEMBL3590617)
Show SMILES CCCCN1C(=O)\C(=C\NCc2ccc(F)cc2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C18H26N6O4/c19-15-11-16(21-8-20-15)24(9-22-11)18-13(26)12(25)14(28-18)17(27)23-10-6-4-2-1-3-5-7-10/h8-10,12-14,18,25-26H,1-7H2,(H,23,27)(H2,19,20,21)/t12?,13?,14-,18+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50072775
PNG
(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Show SMILES CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 |r|
Show InChI InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1
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n/an/an/an/a 7.90n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50211843
PNG
(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)
Show SMILES FC(F)(F)c1nc(Nc2ccc(Cl)cc2Cl)ncc1C(=O)NCC1CCOCC1
Show InChI InChI=1S/C18H17Cl2F3N4O2/c19-11-1-2-14(13(20)7-11)26-17-25-9-12(15(27-17)18(21,22)23)16(28)24-8-10-3-5-29-6-4-10/h1-2,7,9-10H,3-6,8H2,(H,24,28)(H,25,26,27)
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n/an/an/an/a 437n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095863
PNG
(CHEMBL3590611)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(CC)c12
Show InChI InChI=1S/C17H22N6O4/c18-14-10-15(20-5-19-14)23(6-21-10)17-12(25)11(24)13(27-17)16(26)22-9-4-7-1-2-8(9)3-7/h5-9,11-13,17,24-25H,1-4H2,(H,22,26)(H2,18,19,20)/t7?,8?,9?,11?,12?,13-,17+/m0/s1
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n/an/an/an/a 797n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095866
PNG
(CHEMBL3590608)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H31N7O5/c1-12(28)22-8-6-4-2-3-5-7-9-23-19(31)16-14(29)15(30)20(32-16)27-11-26-13-17(21)24-10-25-18(13)27/h10-11,14-16,20,29-30H,2-9H2,1H3,(H,22,28)(H,23,31)(H2,21,24,25)/t14?,15?,16-,20+/m0/s1
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n/an/an/an/a 320n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095871
PNG
(CHEMBL3590636)
Show SMILES CCCCN1C(=O)\C(=C\NC(CC)CC)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H28N2O2/c1-5-8-12-22-18-14(4)10-9-11-16(18)19(23)17(20(22)24)13-21-15(6-2)7-3/h9-11,13,15,21H,5-8,12H2,1-4H3/b17-13+
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n/an/an/an/a 113n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095878
PNG
(CHEMBL3590629)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C18H24N2O2/c1-5-6-10-20-16-13(4)8-7-9-14(16)17(21)15(18(20)22)11-19-12(2)3/h7-9,11-12,19H,5-6,10H2,1-4H3/b15-11+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095846
PNG
(CHEMBL3590601)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccccc12
Show InChI InChI=1S/C14H20N6O5/c1-6(2)3-24-19-13(23)10-8(21)9(22)14(25-10)20-5-18-7-11(15)16-4-17-12(7)20/h4-6,8-10,14,21-22H,3H2,1-2H3,(H,19,23)(H2,15,16,17)/t8?,9?,10-,14+/m0/s1
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n/an/an/an/a 1.58E+3n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095844
PNG
(CHEMBL3590603)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2c(C)cccc12
Show InChI InChI=1S/C20H32N6O4/c1-2-3-4-5-6-7-8-9-10-22-19(29)16-14(27)15(28)20(30-16)26-12-25-13-17(21)23-11-24-18(13)26/h11-12,14-16,20,27-28H,2-10H2,1H3,(H,22,29)(H2,21,23,24)/t14?,15?,16-,20+/m0/s1
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n/an/an/an/a 341n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095850
PNG
(CHEMBL3590624)
Show SMILES CCCCN1C(=O)\C(=C\NCC2CCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C12H13N5O4/c1-2-5(18)9-7(19)8(20)12(21-9)17-4-16-6-10(13)14-3-15-11(6)17/h1,3-5,7-9,12,18-20H,(H2,13,14,15)/t5?,7?,8?,9-,12-/m1/s1
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n/an/an/an/a 220n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095843
PNG
(CHEMBL3590604)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2c(OC)cccc12
Show InChI InChI=1S/C10H12N6O5/c11-7-3-8(13-1-12-7)16(2-14-3)10-5(18)4(17)6(21-10)9(19)15-20/h1-2,4-6,10,17-18,20H,(H,15,19)(H2,11,12,13)/t4?,5?,6-,10+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095846
PNG
(CHEMBL3590601)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccccc12
Show InChI InChI=1S/C14H20N6O5/c1-6(2)3-24-19-13(23)10-8(21)9(22)14(25-10)20-5-18-7-11(15)16-4-17-12(7)20/h4-6,8-10,14,21-22H,3H2,1-2H3,(H,19,23)(H2,15,16,17)/t8?,9?,10-,14+/m0/s1
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n/an/an/an/a 1.58E+3n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095858
PNG
(CHEMBL3590616)
Show SMILES CCCCN1C(=O)\C(=C\NC23CC4CC(CC(C4)C2)C3)C(=O)c2cccc(C)c12 |TLB:17:12:19:16.18.15,17:16:19:11.12.13,THB:15:14:11:17.16.18,15:16:11:19.13.14|
Show InChI InChI=1S/C25H32N2O2/c1-3-4-8-27-22-16(2)6-5-7-20(22)23(28)21(24(27)29)15-26-25-12-17-9-18(13-25)11-19(10-17)14-25/h5-7,15,17-19,26H,3-4,8-14H2,1-2H3/b21-15+
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095846
PNG
(CHEMBL3590601)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccccc12
Show InChI InChI=1S/C14H20N6O5/c1-6(2)3-24-19-13(23)10-8(21)9(22)14(25-10)20-5-18-7-11(15)16-4-17-12(7)20/h4-6,8-10,14,21-22H,3H2,1-2H3,(H,19,23)(H2,15,16,17)/t8?,9?,10-,14+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095855
PNG
(CHEMBL3590619)
Show SMILES CCCCN1C(=O)\C(=C\Nc2ccc(F)cc2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C14H19N7O5/c1-6(22)16-2-3-17-13(25)10-8(23)9(24)14(26-10)21-5-20-7-11(15)18-4-19-12(7)21/h4-5,8-10,14,23-24H,2-3H2,1H3,(H,16,22)(H,17,25)(H2,15,18,19)/t8?,9?,10-,14+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095857
PNG
(CHEMBL3590617)
Show SMILES CCCCN1C(=O)\C(=C\NCc2ccc(F)cc2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C18H26N6O4/c19-15-11-16(21-8-20-15)24(9-22-11)18-13(26)12(25)14(28-18)17(27)23-10-6-4-2-1-3-5-7-10/h8-10,12-14,18,25-26H,1-7H2,(H,23,27)(H2,19,20,21)/t12?,13?,14-,18+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095862
PNG
(CHEMBL3590612)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(CC)c12
Show InChI InChI=1S/C22H36N6O4/c1-2-3-4-5-6-7-8-9-10-11-12-24-21(31)18-16(29)17(30)22(32-18)28-14-27-15-19(23)25-13-26-20(15)28/h13-14,16-18,22,29-30H,2-12H2,1H3,(H,24,31)(H2,23,25,26)/t16?,17?,18-,22+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095864
PNG
(CHEMBL3590610)
Show SMILES Cc1cccc2C(=O)\C(=C/NC3CCCCC3)C(=O)N(CCC=C)c12
Show InChI InChI=1S/C11H14N6O4/c1-13-10(20)7-5(18)6(19)11(21-7)17-3-16-4-8(12)14-2-15-9(4)17/h2-3,5-7,11,18-19H,1H3,(H,13,20)(H2,12,14,15)/t5?,6?,7-,11+/m0/s1
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n/an/an/an/a 748n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095869
PNG
(CHEMBL3590638)
Show SMILES CCCN1C(=O)\C(=C\NC(C)(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H24N6O4/c20-15-11-16(22-6-21-15)25(7-23-11)18-13(27)12(26)14(29-18)17(28)24-19-3-8-1-9(4-19)10(2-8)5-19/h6-10,12-14,18,26-27H,1-5H2,(H,24,28)(H2,20,21,22)/t8?,9?,10?,12?,13?,14-,18+,19?/m0/s1
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n/an/an/an/a 36n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095845
PNG
(CHEMBL3590602)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2ccccc12
Show InChI InChI=1S/C15H22N6O4/c1-2-3-4-5-17-14(24)11-9(22)10(23)15(25-11)21-7-20-8-12(16)18-6-19-13(8)21/h6-7,9-11,15,22-23H,2-5H2,1H3,(H,17,24)(H2,16,18,19)/t9?,10?,11-,15+/m0/s1
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n/an/an/an/a 472n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095853
PNG
(CHEMBL3590621)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H26N2O2/c1-3-4-12-22-18-14(2)8-7-11-16(18)19(23)17(20(22)24)13-21-15-9-5-6-10-15/h7-8,11,13,15,21H,3-6,9-10,12H2,1-2H3/b17-13+
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n/an/an/an/a 58n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095874
PNG
(CHEMBL3590633)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)(C)CO)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H26N2O3/c1-5-6-10-21-16-13(2)8-7-9-14(16)17(23)15(18(21)24)11-20-19(3,4)12-22/h7-9,11,20,22H,5-6,10,12H2,1-4H3/b15-11+
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095867
PNG
(CHEMBL3590639)
Show SMILES Cc1cccc2C(=O)\C(=C/NC(C)(C)C)C(=O)N(CCC=C)c12
Show InChI InChI=1S/C14H20N6O4/c1-14(2,3)19-12(23)9-7(21)8(22)13(24-9)20-5-18-6-10(15)16-4-17-11(6)20/h4-5,7-9,13,21-22H,1-3H3,(H,19,23)(H2,15,16,17)/t7?,8?,9-,13+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095869
PNG
(CHEMBL3590638)
Show SMILES CCCN1C(=O)\C(=C\NC(C)(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H24N6O4/c20-15-11-16(22-6-21-15)25(7-23-11)18-13(27)12(26)14(29-18)17(28)24-19-3-8-1-9(4-19)10(2-8)5-19/h6-10,12-14,18,26-27H,1-5H2,(H,24,28)(H2,20,21,22)/t8?,9?,10?,12?,13?,14-,18+,19?/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095854
PNG
(CHEMBL3590620)
Show SMILES CCCCN1C(=O)\C(=C\Nc2ccccn2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C17H26N6O4/c1-2-3-4-5-6-7-19-16(26)13-11(24)12(25)17(27-13)23-9-22-10-14(18)20-8-21-15(10)23/h8-9,11-13,17,24-25H,2-7H2,1H3,(H,19,26)(H2,18,20,21)/t11?,12?,13-,17+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095855
PNG
(CHEMBL3590619)
Show SMILES CCCCN1C(=O)\C(=C\Nc2ccc(F)cc2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C14H19N7O5/c1-6(22)16-2-3-17-13(25)10-8(23)9(24)14(26-10)21-5-20-7-11(15)18-4-19-12(7)21/h4-5,8-10,14,23-24H,2-3H2,1H3,(H,16,22)(H,17,25)(H2,15,18,19)/t8?,9?,10-,14+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095860
PNG
(CHEMBL3590614)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(OC)c12
Show InChI InChI=1S/C17H24N6O4/c1-8-4-2-3-5-9(8)22-16(26)13-11(24)12(25)17(27-13)23-7-21-10-14(18)19-6-20-15(10)23/h6-9,11-13,17,24-25H,2-5H2,1H3,(H,22,26)(H2,18,19,20)/t8?,9?,11?,12?,13-,17+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095864
PNG
(CHEMBL3590610)
Show SMILES Cc1cccc2C(=O)\C(=C/NC3CCCCC3)C(=O)N(CCC=C)c12
Show InChI InChI=1S/C11H14N6O4/c1-13-10(20)7-5(18)6(19)11(21-7)17-3-16-4-8(12)14-2-15-9(4)17/h2-3,5-7,11,18-19H,1H3,(H,13,20)(H2,12,14,15)/t5?,6?,7-,11+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095840
PNG
(CHEMBL3590607)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C12H17N7O4/c13-1-2-15-11(22)8-6(20)7(21)12(23-8)19-4-18-5-9(14)16-3-17-10(5)19/h3-4,6-8,12,20-21H,1-2,13H2,(H,15,22)(H2,14,16,17)/t6?,7?,8-,12+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095842
PNG
(CHEMBL3590605)
Show SMILES CCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C11H14N6O5/c1-21-16-10(20)7-5(18)6(19)11(22-7)17-3-15-4-8(12)13-2-14-9(4)17/h2-3,5-7,11,18-19H,1H3,(H,16,20)(H2,12,13,14)/t5?,6?,7-,11+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095856
PNG
(CHEMBL3590618)
Show SMILES CCCCN1C(=O)\C(=C\NCc2cccnc2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C21H34N6O4/c1-2-3-4-5-6-7-8-9-10-11-23-20(30)17-15(28)16(29)21(31-17)27-13-26-14-18(22)24-12-25-19(14)27/h12-13,15-17,21,28-29H,2-11H2,1H3,(H,23,30)(H2,22,24,25)/t15?,16?,17-,21+/m0/s1
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50072775
PNG
(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Show SMILES CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 |r|
Show InChI InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1
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n/an/an/an/a 31n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095870
PNG
(CHEMBL3590637)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)(C)CC)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H28N2O2/c1-6-8-12-22-17-14(3)10-9-11-15(17)18(23)16(19(22)24)13-21-20(4,5)7-2/h9-11,13,21H,6-8,12H2,1-5H3/b16-13+
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n/an/an/an/a 75n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095879
PNG
(CHEMBL3590628)
Show SMILES CCCCN1C(=O)\C(=C\NCCC)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C18H24N2O2/c1-4-6-11-20-16-13(3)8-7-9-14(16)17(21)15(18(20)22)12-19-10-5-2/h7-9,12,19H,4-6,10-11H2,1-3H3/b15-12+
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Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095858
PNG
(CHEMBL3590616)
Show SMILES CCCCN1C(=O)\C(=C\NC23CC4CC(CC(C4)C2)C3)C(=O)c2cccc(C)c12 |TLB:17:12:19:16.18.15,17:16:19:11.12.13,THB:15:14:11:17.16.18,15:16:11:19.13.14|
Show InChI InChI=1S/C25H32N2O2/c1-3-4-8-27-22-16(2)6-5-7-20(22)23(28)21(24(27)29)15-26-25-12-17-9-18(13-25)11-19(10-17)14-25/h5-7,15,17-19,26H,3-4,8-14H2,1-2H3/b21-15+
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n/an/an/an/a 317n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095854
PNG
(CHEMBL3590620)
Show SMILES CCCCN1C(=O)\C(=C\Nc2ccccn2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C17H26N6O4/c1-2-3-4-5-6-7-19-16(26)13-11(24)12(25)17(27-13)23-9-22-10-14(18)20-8-21-15(10)23/h8-9,11-13,17,24-25H,2-7H2,1H3,(H,19,26)(H2,18,20,21)/t11?,12?,13-,17+/m0/s1
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n/an/an/an/a 2.39E+3n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095852
PNG
(CHEMBL3590622)
Show SMILES CCCCN1C(=O)\C(=C\NC2CC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C18H22N2O2/c1-3-4-10-20-16-12(2)6-5-7-14(16)17(21)15(18(20)22)11-19-13-8-9-13/h5-7,11,13,19H,3-4,8-10H2,1-2H3/b15-11+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095856
PNG
(CHEMBL3590618)
Show SMILES CCCCN1C(=O)\C(=C\NCc2cccnc2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C21H34N6O4/c1-2-3-4-5-6-7-8-9-10-11-23-20(30)17-15(28)16(29)21(31-17)27-13-26-14-18(22)24-12-25-19(14)27/h12-13,15-17,21,28-29H,2-11H2,1H3,(H,23,30)(H2,22,24,25)/t15?,16?,17-,21+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095862
PNG
(CHEMBL3590612)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(CC)c12
Show InChI InChI=1S/C22H36N6O4/c1-2-3-4-5-6-7-8-9-10-11-12-24-21(31)18-16(29)17(30)22(32-18)28-14-27-15-19(23)25-13-26-20(15)28/h13-14,16-18,22,29-30H,2-12H2,1H3,(H,24,31)(H2,23,25,26)/t16?,17?,18-,22+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095866
PNG
(CHEMBL3590608)
Show SMILES CCCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H31N7O5/c1-12(28)22-8-6-4-2-3-5-7-9-23-19(31)16-14(29)15(30)20(32-16)27-11-26-13-17(21)24-10-25-18(13)27/h10-11,14-16,20,29-30H,2-9H2,1H3,(H,22,28)(H,23,31)(H2,21,24,25)/t14?,15?,16-,20+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095852
PNG
(CHEMBL3590622)
Show SMILES CCCCN1C(=O)\C(=C\NC2CC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C18H22N2O2/c1-3-4-10-20-16-12(2)6-5-7-14(16)17(21)15(18(20)22)11-19-13-8-9-13/h5-7,11,13,19H,3-4,8-10H2,1-2H3/b15-11+
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n/an/an/an/a 503n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095877
PNG
(CHEMBL3590630)
Show SMILES CCCCN\C=C1\C(=O)N(CCCC)c2c(C)cccc2C1=O
Show InChI InChI=1S/C19H26N2O2/c1-4-6-11-20-13-16-18(22)15-10-8-9-14(3)17(15)21(19(16)23)12-7-5-2/h8-10,13,20H,4-7,11-12H2,1-3H3/b16-13+
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n/an/an/an/a 91n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095861
PNG
(CHEMBL3590613)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCCC2)C(=O)c2cccc(OC)c12
Show InChI InChI=1S/C18H28N6O4/c1-2-3-4-5-6-7-8-20-17(27)14-12(25)13(26)18(28-14)24-10-23-11-15(19)21-9-22-16(11)24/h9-10,12-14,18,25-26H,2-8H2,1H3,(H,20,27)(H2,19,21,22)/t12?,13?,14-,18+/m0/s1
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n/an/an/an/a 1.42E+3n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095851
PNG
(CHEMBL3590623)
Show SMILES CCCCN1C(=O)\C(=C\NCC2CC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C16H24N6O4/c1-2-3-4-5-6-18-15(25)12-10(23)11(24)16(26-12)22-8-21-9-13(17)19-7-20-14(9)22/h7-8,10-12,16,23-24H,2-6H2,1H3,(H,18,25)(H2,17,19,20)/t10?,11?,12-,16+/m0/s1
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n/an/an/an/a 127n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095848
PNG
(CHEMBL3590626)
Show SMILES CCCCN1C(=O)\C(=C\NN2CCOCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C17H24N6O4/c18-14-10-15(20-7-19-14)23(8-21-10)17-12(25)11(24)13(27-17)16(26)22-9-5-3-1-2-4-6-9/h7-9,11-13,17,24-25H,1-6H2,(H,22,26)(H2,18,19,20)/t11?,12?,13-,17+/m0/s1
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n/an/an/an/a 476n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095875
PNG
(CHEMBL3590632)
Show SMILES CCCCN1C(=O)\C(=C\NC(C)(C)C)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C19H26N2O2/c1-6-7-11-21-16-13(2)9-8-10-14(16)17(22)15(18(21)23)12-20-19(3,4)5/h8-10,12,20H,6-7,11H2,1-5H3/b15-12+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095851
PNG
(CHEMBL3590623)
Show SMILES CCCCN1C(=O)\C(=C\NCC2CC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C16H24N6O4/c1-2-3-4-5-6-18-15(25)12-10(23)11(24)16(26-12)22-8-21-9-13(17)19-7-20-14(9)22/h7-8,10-12,16,23-24H,2-6H2,1H3,(H,18,25)(H2,17,19,20)/t10?,11?,12-,16+/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50095853
PNG
(CHEMBL3590621)
Show SMILES CCCCN1C(=O)\C(=C\NC2CCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H26N2O2/c1-3-4-12-22-18-14(2)8-7-11-16(18)19(23)17(20(22)24)13-21-15-9-5-6-10-15/h7-8,11,13,15,21H,3-6,9-10,12H2,1-2H3/b17-13+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50095849
PNG
(CHEMBL3590625)
Show SMILES CCCCN1C(=O)\C(=C\NN2CCCCC2)C(=O)c2cccc(C)c12
Show InChI InChI=1S/C20H26N6O4/c21-17-13-18(23-6-22-17)26(7-24-13)20-15(28)14(27)16(30-20)19(29)25-12-10-2-8-1-9(4-10)5-11(12)3-8/h6-12,14-16,20,27-28H,1-5H2,(H,25,29)(H2,21,22,23)/t8?,9?,10?,11?,12?,14?,15?,16-,20+/m0/s1
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n/an/an/an/a 993n/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...


J Med Chem 58: 5751-69 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00227
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%