Affinity Data by PubMed id=26191399

PubMed code 26191399

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134204 (CHEMBL3740772) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50135099 (CHEMBL3739636) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50135098 (CHEMBL3741585) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134208 (CHEMBL3742039) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134205 (CHEMBL3741102) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50135104 (CHEMBL3741981) Show SMILES CC(=O)Nc1cccc(c1)C(=O)c1cccc(NC(C)=O)c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134206 (CHEMBL3742032) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 1 (Rattus norvegicus (Rat))	BDBM50135101 (CHEMBL3739701) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of UT-B in rat whole blood after 15 mins by RBC lysis assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134203 (CHEMBL2442435) Show SMILES Nc1ccc2-c3ccc(N)cc3C(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134207 (CHEMBL3741384) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134202 (CHEMBL424175) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50135103 (CHEMBL3741231) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Urea transporter 1 (Rattus norvegicus (Rat))	BDBM50135106 (CHEMBL3739646) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of UT-B in rat whole blood after 15 mins by RBC lysis assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%