Affinity Data by PubMed id=26227772

PubMed code 26227772

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50249134 (4-(4-fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2...) Show SMILES CC(C)c1cc(nc(N)n1)-c1ccc(F)c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	0.316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to 5HT1B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50114920 ((+/-)-Nantenine \| Nantenine \| Nantenine (8)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]GR125743 from 5HT1B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114921 (CHEMBL3608451) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	209	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114874 (CHEMBL3609143) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	299	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114873 (CHEMBL3609140) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	307	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114924 (CHEMBL3609144) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	416	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114926 (CHEMBL3609147) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	419	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	433	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to alpha2C adrenoceptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114920 ((+/-)-Nantenine \| Nantenine \| Nantenine (8)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	543	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114922 (CHEMBL3609141) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	601	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	627	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to 5HT6 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114923 (CHEMBL3609142) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	663	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114925 (CHEMBL3609146) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	715	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	719	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to alpha2A adrenoceptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50114927 (CHEMBL3609148) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT2B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50114873 (CHEMBL3609140) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]GR125743 from 5HT1B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50114874 (CHEMBL3609143) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]GR125743 from 5HT1B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to PBR (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to alpha2B adrenoceptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity to muscarinic M1 receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50114872 (CHEMBL3608450) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Agonist activity at 5HT1B receptor (unknown origin)				Bioorg Med Chem Lett 25: 3451-4 (2015) Article DOI: 10.1016/j.bmcl.2015.07.012 BindingDB Entry DOI: 10.7270/Q2MW2JXN
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%