Affinity Data by PubMed id=26344591

PubMed code 26344591

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118114 (CHEMBL3612230) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118116 (CHEMBL3612232) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118117 (CHEMBL3612233) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118118 (CHEMBL3612234) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118115 (CHEMBL3612231) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 1.5 to 2 hrs by TR-FRET assay				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118127 (CHEMBL3612227) Show SMILES O=C(Nc1ccccc1)Nc1cccc(Sc2ccnc3ccsc23)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118128 (CHEMBL3612228) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118113 (CHEMBL3612229) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118122 (CHEMBL3612325) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	988	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118119 (CHEMBL3612235) Show SMILES O=C(Nc1ccccc1)Nc1ccc(Sc2ccnc3ccsc23)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118120 (CHEMBL3612323) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118123 (CHEMBL3612326) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118121 (CHEMBL3612324) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118124 (CHEMBL3612224) Show SMILES O=C(Nc1ccccc1)Nc1ccccc1Sc1ccnc2ccsc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118126 (CHEMBL3612226) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118125 (CHEMBL3612225) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) Article DOI: 10.1016/j.bmc.2015.08.010 BindingDB Entry DOI: 10.7270/Q27946G5
Universidade do Minho Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%