Affinity Data by PubMed id=26363868

PubMed code 26363868

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 2C8 (Homo sapiens (Human))	BDBM50131697 (CHEMBL3633320) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP2C8 in human Liver microsomes after 5 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50131697 (CHEMBL3633320) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP2C19 in human Liver microsomes after 35 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50131699 (CHEMBL3633321) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human Liver microsomes after 5 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50131699 (CHEMBL3633321) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP2C19 in human Liver microsomes after 35 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50131697 (CHEMBL3633320) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human Liver microsomes after 5 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50131697 (CHEMBL3633320) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human Liver microsomes after 5 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50131699 (CHEMBL3633321) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human Liver microsomes after 5 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50131697 (CHEMBL3633320) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP2C9 in human Liver microsomes after 5 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50131699 (CHEMBL3633321) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP2C9 in human Liver microsomes after 5 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Homo sapiens (Human))	BDBM50131699 (CHEMBL3633321) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NorthShore University HealthSystem Curated by ChEMBL					Assay Description Inhibition of CYP2C8 in human Liver microsomes after 5 mins by LC-MS/MS method				Eur J Med Chem 103: 325-34 (2015) Article DOI: 10.1016/j.ejmech.2015.08.042 BindingDB Entry DOI: 10.7270/Q2639RKN
NorthShore University HealthSystem Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%