Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human)) | BDBM50127666 (CHEMBL3628839) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | <3.16E+4 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Agonist activity at S1P3 receptor (unknown origin) expressed in RBL membranes assessed as GTPgammaS binding after 3 hrs | J Med Chem 58: 8236-56 (2015) Article DOI: 10.1021/acs.jmedchem.5b01102 BindingDB Entry DOI: 10.7270/Q2D50PR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM50127666 (CHEMBL3628839) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Agonist activity at S1P1 receptor (unknown origin) expressed in CHO-K1 cells assessed as beta-arrestin recruitment after 60 mins by chemiluminescence... | J Med Chem 58: 8236-56 (2015) Article DOI: 10.1021/acs.jmedchem.5b01102 BindingDB Entry DOI: 10.7270/Q2D50PR6 | |||||||||||
More data for this Ligand-Target Pair |