Affinity Data by PubMed id=26428872

PubMed code 26428872

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] A (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Manipal College of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of MAO-A in bovine brain mitochondria using serotonin as substrate preincubated for 30 mins measured after 30 mins by spectrofluorimetric ...				Bioorg Med Chem Lett 25: 5281-5 (2015) Article DOI: 10.1016/j.bmcl.2015.09.048 BindingDB Entry DOI: 10.7270/Q2M90BH5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A (Bos taurus)	BDBM15613 (4-chloro-N-(2-morpholin-4-ylethyl)benzamide \| 4-ch...) Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCOCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Manipal College of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of MAO-A in bovine brain mitochondria using serotonin as substrate preincubated for 30 mins measured after 30 mins by spectrofluorimetric ...				Bioorg Med Chem Lett 25: 5281-5 (2015) Article DOI: 10.1016/j.bmcl.2015.09.048 BindingDB Entry DOI: 10.7270/Q2M90BH5
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Bos taurus)	BDBM50065305 (3-[1-(4-Bromo-phenyl)-meth-(Z)-ylidene]-1,3-dihydr...) Show SMILES Brc1ccc(\C=C2/C(=O)Nc3ccccc23)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Manipal College of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of MAO-A in bovine brain mitochondria using serotonin as substrate preincubated for 30 mins measured after 30 mins by spectrofluorimetric ...				Bioorg Med Chem Lett 25: 5281-5 (2015) Article DOI: 10.1016/j.bmcl.2015.09.048 BindingDB Entry DOI: 10.7270/Q2M90BH5
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Bos taurus)	BDBM50130935 (CHEMBL3633200) Show SMILES Brc1cccc(\C=C2/C(=O)Nc3ccccc23)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Manipal College of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of MAO-A in bovine brain mitochondria using serotonin as substrate preincubated for 30 mins measured after 30 mins by spectrofluorimetric ...				Bioorg Med Chem Lett 25: 5281-5 (2015) Article DOI: 10.1016/j.bmcl.2015.09.048 BindingDB Entry DOI: 10.7270/Q2M90BH5
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Bos taurus)	BDBM50130934 (CHEMBL3633198) Show SMILES Clc1ccc(\C=C2/C(=O)Nc3ccccc23)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Manipal College of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of MAO-A in bovine brain mitochondria using serotonin as substrate preincubated for 30 mins measured after 30 mins by spectrofluorimetric ...				Bioorg Med Chem Lett 25: 5281-5 (2015) Article DOI: 10.1016/j.bmcl.2015.09.048 BindingDB Entry DOI: 10.7270/Q2M90BH5
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Bos taurus)	BDBM50130936 (CHEMBL3633204) Show SMILES Brc1ccc(\C=C2/C(=O)Nc3ccccc23)s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Manipal College of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of MAO-A in bovine brain mitochondria using serotonin as substrate preincubated for 30 mins measured after 30 mins by spectrofluorimetric ...				Bioorg Med Chem Lett 25: 5281-5 (2015) Article DOI: 10.1016/j.bmcl.2015.09.048 BindingDB Entry DOI: 10.7270/Q2M90BH5
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%