Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173566 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-chlorophenyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173563 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2-methoxypheny...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173571 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2-nitrophenyl)...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173567 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-chloro-4-flu...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173567 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-chloro-4-flu...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173562 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-methylphenyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173565 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2,3-dichloroph...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173566 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-chlorophenyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173562 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-methylphenyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173570 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(4-chlorophenyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173569 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2,4-dichloroph...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 6.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173573 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(cyclohexyl)thi...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173568 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2-chlorophenyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173572 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-methoxypheny...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173568 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2-chlorophenyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173573 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(cyclohexyl)thi...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173569 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2,4-dichloroph...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173563 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2-methoxypheny...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173564 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-fluorophenyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.62E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM173564 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-fluorophenyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM50022775 ((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173571 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2-nitrophenyl)...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173565 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2,3-dichloroph...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173570 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(4-chlorophenyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM50022775 ((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM173572 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-methoxypheny...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Quaid-I-Azam University | Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ... | Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4 | |||||||||||
More data for this Ligand-Target Pair |