Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human)) | BDBM175286 (3-(4-Aminosulfonylphenylamino)-2-(4-fluorophenyl)-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human)) | BDBM175285 (3-(4-Aminosulfonylphenylamino)-2-(4-chlorophenyl)-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human)) | BDBM60580 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-trifl...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human)) | BDBM175280 (2-(4-(4-Nitrophenyl)thiazol-2-ylimino)thiazolidin-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human)) | BDBM175284 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-methy...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human)) | BDBM175282 (2-(4-(4-Methanesulfonamidophenyl)thiazol-2-ylimino...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human)) | BDBM175281 (2-(4-(4-Isobutylphenyl)thiazol-2-ylimino)thiazolid...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human)) | BDBM175283 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-phenyl-4...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM175285 (3-(4-Aminosulfonylphenylamino)-2-(4-chlorophenyl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM175286 (3-(4-Aminosulfonylphenylamino)-2-(4-fluorophenyl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM60580 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-trifl...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM175280 (2-(4-(4-Nitrophenyl)thiazol-2-ylimino)thiazolidin-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM175282 (2-(4-(4-Methanesulfonamidophenyl)thiazol-2-ylimino...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM175284 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-methy...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM175281 (2-(4-(4-Isobutylphenyl)thiazol-2-ylimino)thiazolid...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM175283 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-phenyl-4...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beni Suef University | Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki... | Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R | |||||||||||
More data for this Ligand-Target Pair |