Affinity Data by PubMed id=26752095

PubMed code 26752095

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50139126 (CHEMBL3753320) Show SMILES CC(NCc1cc2ccccc2[nH]1)c1ccc(F)c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	131	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50140173 (CHEMBL3753306) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50139126 (CHEMBL3753320) Show SMILES CC(NCc1cc2ccccc2[nH]1)c1ccc(F)c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	132	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50140175 (CHEMBL3753729) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	135	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50404271 (CHEMBL2092942) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	132	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50139127 (CHEMBL3753595) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50140173 (CHEMBL3753306) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50404271 (CHEMBL2092942) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	132	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50140170 (CHEMBL3754639) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	102	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50140170 (CHEMBL3754639) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	102	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50140175 (CHEMBL3753729) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	136	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Rattus norvegicus)	BDBM50139127 (CHEMBL3753595) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) Article DOI: 10.1016/j.bmc.2015.12.019 BindingDB Entry DOI: 10.7270/Q2TX3H7V
CNRS Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%