Affinity Data by PubMed id=26773755

PubMed code 26773755

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosinase (Mus musculus (Mouse))	BDBM175278 ((E)-2,3-bis(4-Hydroxyphenyl)acrylonitrile (21)) Show SMILES Oc1ccc(\C=C(\C#N)c2ccc(O)cc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.06E+3	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM23926 ((E)-resveratrol \| 5-[(E)-2-(4-hydroxyphenyl)etheny...) Show SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175269 (Trans-4-Styryl-phenol (8)) Show SMILES Oc1ccc(\C=C/c2ccccc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175267 (Trans-4-Styrylbenzonitrile (6)) Show SMILES N#Cc1ccc(\C=C/c2ccccc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175271 (Trans-1-fluoro-4-(4-methoxystyryl)benzene (10)) Show SMILES COc1ccc(\C=C/c2ccc(F)cc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175272 (Trans-2-Bromo-1-methoxy-4-styryl-benzene (11)) Show SMILES COc1ccc(\C=C/c2ccccc2)cc1Br Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.62E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175263 (Trans-1-Fluoro-4-styryl-benzene (2)) Show SMILES Fc1ccc(\C=C/c2ccccc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.94E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175275 (Trans-9-Styryl-anthracene (15)) Show SMILES C(=C\c1c2ccccc2cc2ccccc12)\c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175279 ((E)-2-(4-Hydroxyphenyl)-3-(pyridin-3-yl)acrylonitr...) Show SMILES Oc1ccc(cc1)C(=C/c1cccnc1)\C#N Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175277 ((E)-3-(4-Methoxyphenyl)-2-phenylpropenal (20)) Show SMILES COc1ccc(\C=C(\C=O)c2ccccc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.76E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175265 (Trans-1-Bromo-4-styrylbenzene (4)) Show SMILES Brc1ccc(\C=C/c2ccccc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.77E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175264 (Trans-1-Chloro-4-styrylbenzene (3)) Show SMILES Clc1ccc(\C=C/c2ccccc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175266 (Trans-1-Nitro-4-styrylbenzene (5)) Show SMILES [O-][N+](=O)c1ccc(\C=C/c2ccccc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.61E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175273 (Trans-1,3-Difluoro-5-styrylbenzene (12)) Show SMILES Fc1cc(F)cc(\C=C/c2ccccc2)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.94E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175270 (Trans-1-Methoxy-4-styryl-benzene (9)) Show SMILES COc1ccc(\C=C/c2ccccc2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.33E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175276 ((E)-Methyl-3-(4-hydroxy-3-methoxyphenyl)-2-(4-meth...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175268 (Trans-Acetic acid 4-styryl-phenyl ester (7)) Show SMILES CC(=O)Oc1ccc(C=Cc2ccccc2)cc1 \|w:9.9\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175274 (Trans-1,2,3,4,5-Pentafluoro-6-styryl-benzene (14)) Show SMILES Fc1c(F)c(F)c(\C=C/c2ccccc2)c(F)c1F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175262 (Trans-1,2-Diphenylethene (1)) Show SMILES C(=C/c1ccccc1)\c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50006677 (1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
Indian Institute of Integrative Medicine					More data for this Ligand-Target Pair

* indicates data uncertainty>20%