BindingDB logo
myBDB logout

PubMed code 26826581

Compile data set for download or QSAR
Found 40 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM16673
PNG
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
DrugBank
PDB
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144600
PNG
(CHEMBL3759190)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4Cl)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C30H33ClN6O3/c1-36-13-15-37(16-14-36)12-5-17-40-28-19-26-24(18-27(28)39-2)29(33-20-32-26)34-21-8-10-22(11-9-21)35-30(38)23-6-3-4-7-25(23)31/h3-4,6-11,18-20H,5,12-17H2,1-2H3,(H,35,38)(H,32,33,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM16673
PNG
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 80n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144602
PNG
(CHEMBL3759127)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C30H34N6O3/c1-35-14-16-36(17-15-35)13-6-18-39-28-20-26-25(19-27(28)38-2)29(32-21-31-26)33-23-9-11-24(12-10-23)34-30(37)22-7-4-3-5-8-22/h3-5,7-12,19-21H,6,13-18H2,1-2H3,(H,34,37)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144601
PNG
(CHEMBL3758749)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C30H33ClN6O3/c1-36-12-14-37(15-13-36)11-4-16-40-28-19-26-25(18-27(28)39-2)29(33-20-32-26)34-23-7-9-24(10-8-23)35-30(38)21-5-3-6-22(31)17-21/h3,5-10,17-20H,4,11-16H2,1-2H3,(H,35,38)(H,32,33,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144590
PNG
(CHEMBL3759015)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)cc3)ncnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C29H30ClN5O4/c1-37-26-17-24-25(18-27(26)39-13-3-10-35-11-14-38-15-12-35)31-19-32-28(24)33-22-6-8-23(9-7-22)34-29(36)20-4-2-5-21(30)16-20/h2,4-9,16-19H,3,10-15H2,1H3,(H,34,36)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 230n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144589
PNG
(CHEMBL3759848)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)cc3)ncnc2cc1OCCN1CCCCC1
Show InChI InChI=1S/C29H30ClN5O3/c1-37-26-17-24-25(18-27(26)38-15-14-35-12-3-2-4-13-35)31-19-32-28(24)33-22-8-10-23(11-9-22)34-29(36)20-6-5-7-21(30)16-20/h5-11,16-19H,2-4,12-15H2,1H3,(H,34,36)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 300n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144602
PNG
(CHEMBL3759127)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C30H34N6O3/c1-35-14-16-36(17-15-35)13-6-18-39-28-20-26-25(19-27(28)38-2)29(32-21-31-26)33-23-9-11-24(12-10-23)34-30(37)22-7-4-3-5-8-22/h3-5,7-12,19-21H,6,13-18H2,1-2H3,(H,34,37)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 560n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144598
PNG
(CHEMBL3758585)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C31H36N6O3/c1-22-5-7-23(8-6-22)31(38)35-25-11-9-24(10-12-25)34-30-26-19-28(39-3)29(20-27(26)32-21-33-30)40-18-4-13-37-16-14-36(2)15-17-37/h5-12,19-21H,4,13-18H2,1-3H3,(H,35,38)(H,32,33,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 690n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144606
PNG
(CHEMBL3759203)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4Cl)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C29H23ClN4O3/c1-36-26-15-23-25(16-27(26)37-17-19-7-3-2-4-8-19)31-18-32-28(23)33-20-11-13-21(14-12-20)34-29(35)22-9-5-6-10-24(22)30/h2-16,18H,17H2,1H3,(H,34,35)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 730n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144593
PNG
(CHEMBL3758875)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C30H33N5O4/c1-21-4-6-22(7-5-21)30(36)34-24-10-8-23(9-11-24)33-29-25-18-27(37-2)28(19-26(25)31-20-32-29)39-15-3-12-35-13-16-38-17-14-35/h4-11,18-20H,3,12-17H2,1-2H3,(H,34,36)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 760n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144598
PNG
(CHEMBL3758585)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C31H36N6O3/c1-22-5-7-23(8-6-22)31(38)35-25-11-9-24(10-12-25)34-30-26-19-28(39-3)29(20-27(26)32-21-33-30)40-18-4-13-37-16-14-36(2)15-17-37/h5-12,19-21H,4,13-18H2,1-3H3,(H,35,38)(H,32,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 870n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144597
PNG
(CHEMBL3759830)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccc(Nc2ncnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)cc1
Show InChI InChI=1S/C31H36N6O4/c1-36-14-16-37(17-15-36)13-4-18-41-29-20-27-26(19-28(29)40-3)30(33-21-32-27)34-23-7-9-24(10-8-23)35-31(38)22-5-11-25(39-2)12-6-22/h5-12,19-21H,4,13-18H2,1-3H3,(H,35,38)(H,32,33,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.11E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144599
PNG
(CHEMBL3760090)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C30H33ClN6O3/c1-36-13-15-37(16-14-36)12-3-17-40-28-19-26-25(18-27(28)39-2)29(33-20-32-26)34-23-8-10-24(11-9-23)35-30(38)21-4-6-22(31)7-5-21/h4-11,18-20H,3,12-17H2,1-2H3,(H,35,38)(H,32,33,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.33E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144595
PNG
(CHEMBL3759754)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)ncnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C29H30ClN5O4/c1-37-26-17-24-25(18-27(26)39-14-2-11-35-12-15-38-16-13-35)31-19-32-28(24)33-22-7-9-23(10-8-22)34-29(36)20-3-5-21(30)6-4-20/h3-10,17-19H,2,11-16H2,1H3,(H,34,36)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.35E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144600
PNG
(CHEMBL3759190)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4Cl)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C30H33ClN6O3/c1-36-13-15-37(16-14-36)12-5-17-40-28-19-26-24(18-27(28)39-2)29(33-20-32-26)34-21-8-10-22(11-9-21)35-30(38)23-6-3-4-7-25(23)31/h3-4,6-11,18-20H,5,12-17H2,1-2H3,(H,35,38)(H,32,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.71E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144601
PNG
(CHEMBL3758749)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C30H33ClN6O3/c1-36-12-14-37(15-13-36)11-4-16-40-28-19-26-25(18-27(28)39-2)29(33-20-32-26)34-23-7-9-24(10-8-23)35-30(38)21-5-3-6-22(31)17-21/h3,5-10,17-20H,4,11-16H2,1-2H3,(H,35,38)(H,32,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.81E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144599
PNG
(CHEMBL3760090)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C30H33ClN6O3/c1-36-13-15-37(16-14-36)12-3-17-40-28-19-26-25(18-27(28)39-2)29(33-20-32-26)34-23-8-10-24(11-9-23)35-30(38)21-4-6-22(31)7-5-21/h4-11,18-20H,3,12-17H2,1-2H3,(H,35,38)(H,32,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.86E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144589
PNG
(CHEMBL3759848)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)cc3)ncnc2cc1OCCN1CCCCC1
Show InChI InChI=1S/C29H30ClN5O3/c1-37-26-17-24-25(18-27(26)38-15-14-35-12-3-2-4-13-35)31-19-32-28(24)33-22-8-10-23(11-9-22)34-29(36)20-6-5-7-21(30)16-20/h5-11,16-19H,2-4,12-15H2,1H3,(H,34,36)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.99E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144593
PNG
(CHEMBL3758875)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C30H33N5O4/c1-21-4-6-22(7-5-21)30(36)34-24-10-8-23(9-11-24)33-29-25-18-27(37-2)28(19-26(25)31-20-32-29)39-15-3-12-35-13-16-38-17-14-35/h4-11,18-20H,3,12-17H2,1-2H3,(H,34,36)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144597
PNG
(CHEMBL3759830)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccc(Nc2ncnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)cc1
Show InChI InChI=1S/C31H36N6O4/c1-36-14-16-37(17-15-36)13-4-18-41-29-20-27-26(19-28(29)40-3)30(33-21-32-27)34-23-7-9-24(10-8-23)35-31(38)22-5-11-25(39-2)12-6-22/h5-12,19-21H,4,13-18H2,1-3H3,(H,35,38)(H,32,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.02E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144592
PNG
(CHEMBL3758363)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCCN1CCCCC1
Show InChI InChI=1S/C30H33N5O3/c1-21-6-8-22(9-7-21)30(36)34-24-12-10-23(11-13-24)33-29-25-18-27(37-2)28(19-26(25)31-20-32-29)38-17-16-35-14-4-3-5-15-35/h6-13,18-20H,3-5,14-17H2,1-2H3,(H,34,36)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.48E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144595
PNG
(CHEMBL3759754)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)ncnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C29H30ClN5O4/c1-37-26-17-24-25(18-27(26)39-14-2-11-35-12-15-38-16-13-35)31-19-32-28(24)33-22-7-9-23(10-8-22)34-29(36)20-3-5-21(30)6-4-20/h3-10,17-19H,2,11-16H2,1H3,(H,34,36)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.62E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144590
PNG
(CHEMBL3759015)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)cc3)ncnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C29H30ClN5O4/c1-37-26-17-24-25(18-27(26)39-13-3-10-35-11-14-38-15-12-35)31-19-32-28(24)33-22-6-8-23(9-7-22)34-29(36)20-4-2-5-21(30)16-20/h2,4-9,16-19H,3,10-15H2,1H3,(H,34,36)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.99E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144594
PNG
(CHEMBL3758796)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)ncnc2cc1OCCN1CCCCC1
Show InChI InChI=1S/C29H30ClN5O3/c1-37-26-17-24-25(18-27(26)38-16-15-35-13-3-2-4-14-35)31-19-32-28(24)33-22-9-11-23(12-10-22)34-29(36)20-5-7-21(30)8-6-20/h5-12,17-19H,2-4,13-16H2,1H3,(H,34,36)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.19E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144596
PNG
(CHEMBL3759155)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCN1CCCCC1
Show InChI InChI=1S/C29H31N5O3/c1-36-26-18-24-25(19-27(26)37-17-16-34-14-6-3-7-15-34)30-20-31-28(24)32-22-10-12-23(13-11-22)33-29(35)21-8-4-2-5-9-21/h2,4-5,8-13,18-20H,3,6-7,14-17H2,1H3,(H,33,35)(H,30,31,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.61E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144596
PNG
(CHEMBL3759155)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCN1CCCCC1
Show InChI InChI=1S/C29H31N5O3/c1-36-26-18-24-25(19-27(26)37-17-16-34-14-6-3-7-15-34)30-20-31-28(24)32-22-10-12-23(13-11-22)33-29(35)21-8-4-2-5-9-21/h2,4-5,8-13,18-20H,3,6-7,14-17H2,1H3,(H,33,35)(H,30,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.72E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144605
PNG
(CHEMBL3758355)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C29H23ClN4O3/c1-36-26-15-24-25(16-27(26)37-17-19-5-3-2-4-6-19)31-18-32-28(24)33-22-11-13-23(14-12-22)34-29(35)20-7-9-21(30)10-8-20/h2-16,18H,17H2,1H3,(H,34,35)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144605
PNG
(CHEMBL3758355)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C29H23ClN4O3/c1-36-26-15-24-25(16-27(26)37-17-19-5-3-2-4-6-19)31-18-32-28(24)33-22-11-13-23(14-12-22)34-29(35)20-7-9-21(30)10-8-20/h2-16,18H,17H2,1H3,(H,34,35)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144594
PNG
(CHEMBL3758796)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)ncnc2cc1OCCN1CCCCC1
Show InChI InChI=1S/C29H30ClN5O3/c1-37-26-17-24-25(18-27(26)38-16-15-35-13-3-2-4-14-35)31-19-32-28(24)33-22-9-11-23(12-10-22)34-29(36)20-5-7-21(30)8-6-20/h5-12,17-19H,2-4,13-16H2,1H3,(H,34,36)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144604
PNG
(CHEMBL3758900)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C30H26N4O3/c1-20-8-10-22(11-9-20)30(35)34-24-14-12-23(13-15-24)33-29-25-16-27(36-2)28(17-26(25)31-19-32-29)37-18-21-6-4-3-5-7-21/h3-17,19H,18H2,1-2H3,(H,34,35)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144603
PNG
(CHEMBL3759884)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccc(Nc2ncnc3cc(OCc4ccccc4)c(OC)cc23)cc1
Show InChI InChI=1S/C30H26N4O4/c1-36-24-14-8-21(9-15-24)30(35)34-23-12-10-22(11-13-23)33-29-25-16-27(37-2)28(17-26(25)31-19-32-29)38-18-20-6-4-3-5-7-20/h3-17,19H,18H2,1-2H3,(H,34,35)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144608
PNG
(CHEMBL3759724)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C29H24N4O3/c1-35-26-16-24-25(17-27(26)36-18-20-8-4-2-5-9-20)30-19-31-28(24)32-22-12-14-23(15-13-22)33-29(34)21-10-6-3-7-11-21/h2-17,19H,18H2,1H3,(H,33,34)(H,30,31,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144592
PNG
(CHEMBL3758363)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCCN1CCCCC1
Show InChI InChI=1S/C30H33N5O3/c1-21-6-8-22(9-7-21)30(36)34-24-12-10-23(11-13-24)33-29-25-18-27(37-2)28(19-26(25)31-20-32-29)38-17-16-35-14-4-3-5-15-35/h6-13,18-20H,3-5,14-17H2,1-2H3,(H,34,36)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144603
PNG
(CHEMBL3759884)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccc(Nc2ncnc3cc(OCc4ccccc4)c(OC)cc23)cc1
Show InChI InChI=1S/C30H26N4O4/c1-36-24-14-8-21(9-15-24)30(35)34-23-12-10-22(11-13-23)33-29-25-16-27(37-2)28(17-26(25)31-19-32-29)38-18-20-6-4-3-5-7-20/h3-17,19H,18H2,1-2H3,(H,34,35)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144607
PNG
(CHEMBL3759483)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C29H23ClN4O3/c1-36-26-15-24-25(16-27(26)37-17-19-6-3-2-4-7-19)31-18-32-28(24)33-22-10-12-23(13-11-22)34-29(35)20-8-5-9-21(30)14-20/h2-16,18H,17H2,1H3,(H,34,35)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50144604
PNG
(CHEMBL3758900)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C30H26N4O3/c1-20-8-10-22(11-9-20)30(35)34-24-14-12-23(13-15-24)33-29-25-16-27(36-2)28(17-26(25)31-19-32-29)37-18-21-6-4-3-5-7-21/h3-17,19H,18H2,1-2H3,(H,34,35)(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144608
PNG
(CHEMBL3759724)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C29H24N4O3/c1-35-26-16-24-25(17-27(26)36-18-20-8-4-2-5-9-20)30-19-31-28(24)32-22-12-14-23(15-13-22)33-29(34)21-10-6-3-7-11-21/h2-17,19H,18H2,1H3,(H,33,34)(H,30,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144606
PNG
(CHEMBL3759203)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4Cl)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C29H23ClN4O3/c1-36-26-15-23-25(16-27(26)37-17-19-7-3-2-4-8-19)31-18-32-28(23)33-20-11-13-21(14-12-20)34-29(35)22-9-5-6-10-24(22)30/h2-16,18H,17H2,1H3,(H,34,35)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50144607
PNG
(CHEMBL3759483)
Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)cc3)ncnc2cc1OCc1ccccc1
Show InChI InChI=1S/C29H23ClN4O3/c1-36-26-15-24-25(16-27(26)37-17-19-6-3-2-4-7-19)31-18-32-28(24)33-22-10-12-23(13-11-22)34-29(35)20-8-5-9-21(30)14-20/h2-16,18H,17H2,1H3,(H,34,35)(H,31,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...

Eur J Med Chem 109: 371-9 (2016)


Article DOI: 10.1016/j.ejmech.2015.12.032
BindingDB Entry DOI: 10.7270/Q2M32XKS
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%