Found 89 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150632
(CHEMBL3770838)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCc1ccc(B(O)O)c(OC)c1 Show InChI InChI=1S/C26H44BNO4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)28-22-23-19-20-24(27(30)31)25(21-23)32-2/h10-11,19-21,30-31H,3-9,12-18,22H2,1-2H3,(H,28,29)/b11-10- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150639
(CHEMBL3770079)Show InChI InChI=1S/C22H30BNO4/c1-28-21-16-19(14-15-20(21)23(26)27)17-24-22(25)13-9-4-2-3-6-10-18-11-7-5-8-12-18/h5,7-8,11-12,14-16,26-27H,2-4,6,9-10,13,17H2,1H3,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150637
(CHEMBL3770653)Show InChI InChI=1S/C15H13BClNO3/c17-13-7-4-11(5-8-13)6-9-15(19)18-14-3-1-2-12(10-14)16(20)21/h1-10,20-21H,(H,18,19)/b9-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150630
(CHEMBL3770603)Show InChI InChI=1S/C25H42BNO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-25(28)27-22-23-18-20-24(21-19-23)26(29)30/h9-10,18-21,29-30H,2-8,11-17,22H2,1H3,(H,27,28)/b10-9- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150582
(CHEMBL3771141)Show InChI InChI=1S/C19H16BNO3/c22-19(16-6-10-17(11-7-16)20(23)24)21-18-12-8-15(9-13-18)14-4-2-1-3-5-14/h1-13,23-24H,(H,21,22) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150578
(CHEMBL3769906)Show InChI InChI=1S/C18H22BNO3/c21-18(16-10-12-17(13-11-16)19(22)23)20-14-6-2-5-9-15-7-3-1-4-8-15/h1,3-4,7-8,10-13,22-23H,2,5-6,9,14H2,(H,20,21) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150577
(CHEMBL3769611)Show InChI InChI=1S/C16H18BNO3/c19-16(11-8-13-4-2-1-3-5-13)18-12-14-6-9-15(10-7-14)17(20)21/h1-7,9-10,20-21H,8,11-12H2,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150624
(CHEMBL3770697)Show InChI InChI=1S/C21H28BNO3/c24-21(17-19-12-14-20(15-13-19)22(25)26)23-16-8-3-1-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-15,25-26H,1-3,5,8-9,16-17H2,(H,23,24) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150634
(CHEMBL3770435)Show InChI InChI=1S/C21H27NO2/c23-20-14-12-19(13-15-20)17-21(24)22-16-8-3-1-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-15,23H,1-3,5,8-9,16-17H2,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20488
((2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-...)Show InChI InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in CHO cells assessed as inhibition of capsiacin-induced Ca2+ flux by Fluo-3 dye bas... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20488
((2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-...)Show InChI InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in CHO cells assessed as inhibition of capsiacin-induced Ca2+ flux by Fluo-3 dye bas... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150631
(CHEMBL3770620)Show InChI InChI=1S/C21H20BNO3/c24-21(14-16-8-12-20(13-9-16)22(25)26)23-15-17-6-10-19(11-7-17)18-4-2-1-3-5-18/h1-13,25-26H,14-15H2,(H,23,24) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150627
(CHEMBL3769572)Show InChI InChI=1S/C20H18BNO3/c23-20(22-14-15-6-12-19(13-7-15)21(24)25)18-10-8-17(9-11-18)16-4-2-1-3-5-16/h1-13,24-25H,14H2,(H,22,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150624
(CHEMBL3770697)Show InChI InChI=1S/C21H28BNO3/c24-21(17-19-12-14-20(15-13-19)22(25)26)23-16-8-3-1-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-15,25-26H,1-3,5,8-9,16-17H2,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150584
(CHEMBL3771004)Show InChI InChI=1S/C20H26BNO3/c23-20(22-19-15-13-18(14-16-19)21(24)25)12-8-3-1-2-5-9-17-10-6-4-7-11-17/h4,6-7,10-11,13-16,24-25H,1-3,5,8-9,12H2,(H,22,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150544
(CHEMBL3770115)Show InChI InChI=1S/C21H28BNO3/c24-21(23-17-19-13-15-20(16-14-19)22(25)26)12-8-3-1-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-11,13-16,25-26H,1-3,5,8-9,12,17H2,(H,23,24) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150544
(CHEMBL3770115)Show InChI InChI=1S/C21H28BNO3/c24-21(23-17-19-13-15-20(16-14-19)22(25)26)12-8-3-1-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-11,13-16,25-26H,1-3,5,8-9,12,17H2,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150623
(CHEMBL3771001)Show InChI InChI=1S/C15H13BClNO3/c17-13-6-1-11(2-7-13)3-10-15(19)18-14-8-4-12(5-9-14)16(20)21/h1-10,20-21H,(H,18,19)/b10-3+ | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150587
(CHEMBL3769734)Show InChI InChI=1S/C18H22BNO3/c21-18(20-17-13-11-16(12-14-17)19(22)23)10-6-2-5-9-15-7-3-1-4-8-15/h1,3-4,7-8,11-14,22-23H,2,5-6,9-10H2,(H,20,21) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150545
(CHEMBL3769782)Show InChI InChI=1S/C17H20BNO3/c20-17(15-9-11-16(12-10-15)18(21)22)19-13-5-4-8-14-6-2-1-3-7-14/h1-3,6-7,9-12,21-22H,4-5,8,13H2,(H,19,20) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150628
(CHEMBL3769510)Show InChI InChI=1S/C19H24BNO3/c22-19(15-17-10-12-18(13-11-17)20(23)24)21-14-6-2-5-9-16-7-3-1-4-8-16/h1,3-4,7-8,10-13,23-24H,2,5-6,9,14-15H2,(H,21,22) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150586
(CHEMBL3770207)Show InChI InChI=1S/C17H20BNO3/c1-17(2,3)13-6-10-15(11-7-13)19-16(20)12-4-8-14(9-5-12)18(21)22/h4-11,21-22H,1-3H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150625
(CHEMBL3771273)Show InChI InChI=1S/C17H20BNO3/c1-17(2,3)13-6-4-12(5-7-13)16(20)19-15-10-8-14(9-11-15)18(21)22/h4-11,21-22H,1-3H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM26132
((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)Show InChI InChI=1S/C12H11BO2/c14-13(15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,14-15H | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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| Purchase
MCE
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150521
(CHEMBL3769556)Show InChI InChI=1S/C19H24BNO3/c22-19(10-6-2-5-9-16-7-3-1-4-8-16)21-15-17-11-13-18(14-12-17)20(23)24/h1,3-4,7-8,11-14,23-24H,2,5-6,9-10,15H2,(H,21,22) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150626
(CHEMBL3771003)Show InChI InChI=1S/C18H22BNO3/c21-18(14-16-9-11-17(12-10-16)19(22)23)20-13-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-12,22-23H,4-5,8,13-14H2,(H,20,21) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150633
(CHEMBL3769407)Show InChI InChI=1S/C21H27NO/c23-21(18-20-15-9-5-10-16-20)22-17-11-3-1-2-6-12-19-13-7-4-8-14-19/h4-5,7-10,13-16H,1-3,6,11-12,17-18H2,(H,22,23) | PDB
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Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150638
(CHEMBL3769949)Show InChI InChI=1S/C20H26BNO4/c1-26-19-14-17(12-13-18(19)21(24)25)15-22-20(23)11-7-3-6-10-16-8-4-2-5-9-16/h2,4-5,8-9,12-14,24-25H,3,6-7,10-11,15H2,1H3,(H,22,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150623
(CHEMBL3771001)Show InChI InChI=1S/C15H13BClNO3/c17-13-6-1-11(2-7-13)3-10-15(19)18-14-8-4-12(5-9-14)16(20)21/h1-10,20-21H,(H,18,19)/b10-3+ | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150579
(CHEMBL3770848)Show InChI InChI=1S/C16H15BClNO3/c18-15-8-3-12(4-9-15)5-10-16(20)19-11-13-1-6-14(7-2-13)17(21)22/h1-10,21-22H,11H2,(H,19,20)/b10-5+ | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150638
(CHEMBL3769949)Show InChI InChI=1S/C20H26BNO4/c1-26-19-14-17(12-13-18(19)21(24)25)15-22-20(23)11-7-3-6-10-16-8-4-2-5-9-16/h2,4-5,8-9,12-14,24-25H,3,6-7,10-11,15H2,1H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150639
(CHEMBL3770079)Show InChI InChI=1S/C22H30BNO4/c1-28-21-16-19(14-15-20(21)23(26)27)17-24-22(25)13-9-4-2-3-6-10-18-11-7-5-8-12-18/h5,7-8,11-12,14-16,26-27H,2-4,6,9-10,13,17H2,1H3,(H,24,25) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150581
(CHEMBL3769907)Show InChI InChI=1S/C20H18BNO3/c23-20(18-10-12-19(13-11-18)21(24)25)22-14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13,24-25H,14H2,(H,22,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150636
(CHEMBL3770436)Show InChI InChI=1S/C17H21BN2O3/c1-17(2,3)12-4-8-14(9-5-12)19-16(21)20-15-10-6-13(7-11-15)18(22)23/h4-11,22-23H,1-3H3,(H2,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150520
(CHEMBL3771217)Show InChI InChI=1S/C18H23BN2O3/c1-18(2,3)14-6-10-16(11-7-14)21-17(22)20-12-13-4-8-15(9-5-13)19(23)24/h4-11,23-24H,12H2,1-3H3,(H2,20,21,22) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150626
(CHEMBL3771003)Show InChI InChI=1S/C18H22BNO3/c21-18(14-16-9-11-17(12-10-16)19(22)23)20-13-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-12,22-23H,4-5,8,13-14H2,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150628
(CHEMBL3769510)Show InChI InChI=1S/C19H24BNO3/c22-19(15-17-10-12-18(13-11-17)20(23)24)21-14-6-2-5-9-16-7-3-1-4-8-16/h1,3-4,7-8,10-13,23-24H,2,5-6,9,14-15H2,(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150583
(CHEMBL3770604)Show InChI InChI=1S/C14H14BNO3/c17-14(16-10-11-4-2-1-3-5-11)12-6-8-13(9-7-12)15(18)19/h1-9,18-19H,10H2,(H,16,17) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150521
(CHEMBL3769556)Show InChI InChI=1S/C19H24BNO3/c22-19(10-6-2-5-9-16-7-3-1-4-8-16)21-15-17-11-13-18(14-12-17)20(23)24/h1,3-4,7-8,11-14,23-24H,2,5-6,9-10,15H2,(H,21,22) | PDB
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Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM26134
((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3 | PDB
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PC sid
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| Article
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| n/a | n/a | 2.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150520
(CHEMBL3771217)Show InChI InChI=1S/C18H23BN2O3/c1-18(2,3)14-6-10-16(11-7-14)21-17(22)20-12-13-4-8-15(9-5-13)19(23)24/h4-11,23-24H,12H2,1-3H3,(H2,20,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150522
(CHEMBL3771315)Show SMILES COc1cc(CNC(=O)Nc2ccc(cc2)C(C)(C)C)ccc1B(O)O Show InChI InChI=1S/C19H25BN2O4/c1-19(2,3)14-6-8-15(9-7-14)22-18(23)21-12-13-5-10-16(20(24)25)17(11-13)26-4/h5-11,24-25H,12H2,1-4H3,(H2,21,22,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150586
(CHEMBL3770207)Show InChI InChI=1S/C17H20BNO3/c1-17(2,3)13-6-10-15(11-7-13)19-16(20)12-4-8-14(9-5-12)18(21)22/h4-11,21-22H,1-3H3,(H,19,20) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150631
(CHEMBL3770620)Show InChI InChI=1S/C21H20BNO3/c24-21(14-16-8-12-20(13-9-16)22(25)26)23-15-17-6-10-19(11-7-17)18-4-2-1-3-5-18/h1-13,25-26H,14-15H2,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150627
(CHEMBL3769572)Show InChI InChI=1S/C20H18BNO3/c23-20(22-14-15-6-12-19(13-7-15)21(24)25)18-10-8-17(9-11-18)16-4-2-1-3-5-16/h1-13,24-25H,14H2,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150522
(CHEMBL3771315)Show SMILES COc1cc(CNC(=O)Nc2ccc(cc2)C(C)(C)C)ccc1B(O)O Show InChI InChI=1S/C19H25BN2O4/c1-19(2,3)14-6-8-15(9-7-14)22-18(23)21-12-13-5-10-16(20(24)25)17(11-13)26-4/h5-11,24-25H,12H2,1-4H3,(H2,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM26134
((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150580
(CHEMBL3770113)Show InChI InChI=1S/C15H16BNO4/c18-14-7-1-11(2-8-14)9-10-17-15(19)12-3-5-13(6-4-12)16(20)21/h1-8,18,20-21H,9-10H2,(H,17,19) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150629
(CHEMBL3769866)Show InChI InChI=1S/C15H16BNO3/c18-15(17-11-13-4-2-1-3-5-13)10-12-6-8-14(9-7-12)16(19)20/h1-9,19-20H,10-11H2,(H,17,18) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150578
(CHEMBL3769906)Show InChI InChI=1S/C18H22BNO3/c21-18(16-10-12-17(13-11-16)19(22)23)20-14-6-2-5-9-15-7-3-1-4-8-15/h1,3-4,7-8,10-13,22-23H,2,5-6,9,14H2,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150582
(CHEMBL3771141)Show InChI InChI=1S/C19H16BNO3/c22-19(16-6-10-17(11-7-16)20(23)24)21-18-12-8-15(9-13-18)14-4-2-1-3-5-14/h1-13,23-24H,(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150625
(CHEMBL3771273)Show InChI InChI=1S/C17H20BNO3/c1-17(2,3)13-6-4-12(5-7-13)16(20)19-15-10-8-14(9-11-15)18(21)22/h4-11,21-22H,1-3H3,(H,19,20) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150588
(CHEMBL3769722)Show InChI InChI=1S/C20H18BNO3/c23-20(22-19-12-10-18(11-13-19)21(24)25)14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13,24-25H,14H2,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150545
(CHEMBL3769782)Show InChI InChI=1S/C17H20BNO3/c20-17(15-9-11-16(12-10-15)18(21)22)19-13-5-4-8-14-6-2-1-3-7-14/h1-3,6-7,9-12,21-22H,4-5,8,13H2,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150581
(CHEMBL3769907)Show InChI InChI=1S/C20H18BNO3/c23-20(18-10-12-19(13-11-18)21(24)25)22-14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13,24-25H,14H2,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150577
(CHEMBL3769611)Show InChI InChI=1S/C16H18BNO3/c19-16(11-8-13-4-2-1-3-5-13)18-12-14-6-9-15(10-7-14)17(20)21/h1-7,9-10,20-21H,8,11-12H2,(H,18,19) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150636
(CHEMBL3770436)Show InChI InChI=1S/C17H21BN2O3/c1-17(2,3)12-4-8-14(9-5-12)19-16(21)20-15-10-6-13(7-11-15)18(22)23/h4-11,22-23H,1-3H3,(H2,19,20,21) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150629
(CHEMBL3769866)Show InChI InChI=1S/C15H16BNO3/c18-15(17-11-13-4-2-1-3-5-13)10-12-6-8-14(9-7-12)16(19)20/h1-9,19-20H,10-11H2,(H,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150588
(CHEMBL3769722)Show InChI InChI=1S/C20H18BNO3/c23-20(22-19-12-10-18(11-13-19)21(24)25)14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13,24-25H,14H2,(H,22,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150635
(CHEMBL3770337)Show InChI InChI=1S/C18H22BNO3/c1-18(2,3)14-6-10-16(11-7-14)20-17(21)12-13-4-8-15(9-5-13)19(22)23/h4-11,22-23H,12H2,1-3H3,(H,20,21) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150634
(CHEMBL3770435)Show InChI InChI=1S/C21H27NO2/c23-20-14-12-19(13-15-20)17-21(24)22-16-8-3-1-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-15,23H,1-3,5,8-9,16-17H2,(H,22,24) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150587
(CHEMBL3769734)Show InChI InChI=1S/C18H22BNO3/c21-18(20-17-13-11-16(12-14-17)19(22)23)10-6-2-5-9-15-7-3-1-4-8-15/h1,3-4,7-8,11-14,22-23H,2,5-6,9-10H2,(H,20,21) | PDB
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Reactome pathway
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| CHEMBL
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| Article
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150579
(CHEMBL3770848)Show InChI InChI=1S/C16H15BClNO3/c18-15-8-3-12(4-9-15)5-10-16(20)19-11-13-1-6-14(7-2-13)17(21)22/h1-10,21-22H,11H2,(H,19,20)/b10-5+ | PDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM26132
((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)Show InChI InChI=1S/C12H11BO2/c14-13(15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,14-15H | PDB
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Reactome pathway
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MCE
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150637
(CHEMBL3770653)Show InChI InChI=1S/C15H13BClNO3/c17-13-7-4-11(5-8-13)6-9-15(19)18-14-3-1-2-12(10-14)16(20)21/h1-10,20-21H,(H,18,19)/b9-6+ | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150633
(CHEMBL3769407)Show InChI InChI=1S/C21H27NO/c23-21(18-20-15-9-5-10-16-20)22-17-11-3-1-2-6-12-19-13-7-4-8-14-19/h4-5,7-10,13-16H,1-3,6,11-12,17-18H2,(H,22,23) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150583
(CHEMBL3770604)Show InChI InChI=1S/C14H14BNO3/c17-14(16-10-11-4-2-1-3-5-11)12-6-8-13(9-7-12)15(18)19/h1-9,18-19H,10H2,(H,16,17) | PDB
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KEGG
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CHEMBL
MCE
PC cid
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UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM20488
((2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-...)Show InChI InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+ | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150630
(CHEMBL3770603)Show InChI InChI=1S/C25H42BNO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-25(28)27-22-23-18-20-24(21-19-23)26(29)30/h9-10,18-21,29-30H,2-8,11-17,22H2,1H3,(H,27,28)/b10-9- | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50150632
(CHEMBL3770838)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCc1ccc(B(O)O)c(OC)c1 Show InChI InChI=1S/C26H44BNO4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)28-22-23-19-20-24(27(30)31)25(21-23)32-2/h10-11,19-21,30-31H,3-9,12-18,22H2,1-2H3,(H,28,29)/b11-10- | PDB
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UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150635
(CHEMBL3770337)Show InChI InChI=1S/C18H22BNO3/c1-18(2,3)14-6-10-16(11-7-14)20-17(21)12-13-4-8-15(9-5-13)19(22)23/h4-11,22-23H,12H2,1-3H3,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150580
(CHEMBL3770113)Show InChI InChI=1S/C15H16BNO4/c18-14-7-1-11(2-8-14)9-10-17-15(19)12-3-5-13(6-4-12)16(20)21/h1-8,18,20-21H,9-10H2,(H,17,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150584
(CHEMBL3771004)Show InChI InChI=1S/C20H26BNO3/c23-20(22-19-15-13-18(14-16-19)21(24)25)12-8-3-1-2-5-9-17-10-6-4-7-11-17/h4,6-7,10-11,13-16,24-25H,1-3,5,8-9,12H2,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150521
(CHEMBL3769556)Show InChI InChI=1S/C19H24BNO3/c22-19(10-6-2-5-9-16-7-3-1-4-8-16)21-15-17-11-13-18(14-12-17)20(23)24/h1,3-4,7-8,11-14,23-24H,2,5-6,9-10,15H2,(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.53E+3 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150625
(CHEMBL3771273)Show InChI InChI=1S/C17H20BNO3/c1-17(2,3)13-6-4-12(5-7-13)16(20)19-15-10-8-14(9-11-15)18(21)22/h4-11,21-22H,1-3H3,(H,19,20) | PDB
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Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 520 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150624
(CHEMBL3770697)Show InChI InChI=1S/C21H28BNO3/c24-21(17-19-12-14-20(15-13-19)22(25)26)23-16-8-3-1-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-15,25-26H,1-3,5,8-9,16-17H2,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150631
(CHEMBL3770620)Show InChI InChI=1S/C21H20BNO3/c24-21(14-16-8-12-20(13-9-16)22(25)26)23-15-17-6-10-19(11-7-17)18-4-2-1-3-5-18/h1-13,25-26H,14-15H2,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150628
(CHEMBL3769510)Show InChI InChI=1S/C19H24BNO3/c22-19(15-17-10-12-18(13-11-17)20(23)24)21-14-6-2-5-9-16-7-3-1-4-8-16/h1,3-4,7-8,10-13,23-24H,2,5-6,9,14-15H2,(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.25E+3 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150577
(CHEMBL3769611)Show InChI InChI=1S/C16H18BNO3/c19-16(11-8-13-4-2-1-3-5-13)18-12-14-6-9-15(10-7-14)17(20)21/h1-7,9-10,20-21H,8,11-12H2,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150638
(CHEMBL3769949)Show InChI InChI=1S/C20H26BNO4/c1-26-19-14-17(12-13-18(19)21(24)25)15-22-20(23)11-7-3-6-10-16-8-4-2-5-9-16/h2,4-5,8-9,12-14,24-25H,3,6-7,10-11,15H2,1H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150633
(CHEMBL3769407)Show InChI InChI=1S/C21H27NO/c23-21(18-20-15-9-5-10-16-20)22-17-11-3-1-2-6-12-19-13-7-4-8-14-19/h4-5,7-10,13-16H,1-3,6,11-12,17-18H2,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 660 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150632
(CHEMBL3770838)Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCc1ccc(B(O)O)c(OC)c1 Show InChI InChI=1S/C26H44BNO4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)28-22-23-19-20-24(27(30)31)25(21-23)32-2/h10-11,19-21,30-31H,3-9,12-18,22H2,1-2H3,(H,28,29)/b11-10- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150544
(CHEMBL3770115)Show InChI InChI=1S/C21H28BNO3/c24-21(23-17-19-13-15-20(16-14-19)22(25)26)12-8-3-1-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-11,13-16,25-26H,1-3,5,8-9,12,17H2,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150627
(CHEMBL3769572)Show InChI InChI=1S/C20H18BNO3/c23-20(22-14-15-6-12-19(13-7-15)21(24)25)18-10-8-17(9-11-18)16-4-2-1-3-5-16/h1-13,24-25H,14H2,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.23E+3 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150634
(CHEMBL3770435)Show InChI InChI=1S/C21H27NO2/c23-20-14-12-19(13-15-20)17-21(24)22-16-8-3-1-2-5-9-18-10-6-4-7-11-18/h4,6-7,10-15,23H,1-3,5,8-9,16-17H2,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150639
(CHEMBL3770079)Show InChI InChI=1S/C22H30BNO4/c1-28-21-16-19(14-15-20(21)23(26)27)17-24-22(25)13-9-4-2-3-6-10-18-11-7-5-8-12-18/h5,7-8,11-12,14-16,26-27H,2-4,6,9-10,13,17H2,1H3,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 51 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150630
(CHEMBL3770603)Show InChI InChI=1S/C25H42BNO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-25(28)27-22-23-18-20-24(21-19-23)26(29)30/h9-10,18-21,29-30H,2-8,11-17,22H2,1H3,(H,27,28)/b10-9- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150582
(CHEMBL3771141)Show InChI InChI=1S/C19H16BNO3/c22-19(16-6-10-17(11-7-16)20(23)24)21-18-12-8-15(9-13-18)14-4-2-1-3-5-14/h1-13,23-24H,(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.97E+3 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50150626
(CHEMBL3771003)Show InChI InChI=1S/C18H22BNO3/c21-18(14-16-9-11-17(12-10-16)19(22)23)20-13-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-12,22-23H,4-5,8,13-14H2,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d... |
Bioorg Med Chem Lett 26: 1401-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.071
BindingDB Entry DOI: 10.7270/Q24F1SM9 |
More data for this
Ligand-Target Pair | |
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