Affinity Data by PubMed id=26852623

PubMed code 26852623

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50396483 (PLX-4032 \| RG 7204 \| Ro 5185426 \| US10570155, Vemu...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
NIH Special Volunteer Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged BRAF V600E mutant (448 to 723 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed a...				J Nat Prod 79: 629-61 (2016) Article DOI: 10.1021/acs.jnatprod.5b01055 BindingDB Entry DOI: 10.7270/Q2W37Z73
NIH Special Volunteer Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50172099 (CHEMBL1231605) Show SMILES N(c1c[nH]c2ncccc12)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
NIH Special Volunteer Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged BRAF V600E mutant (448 to 723 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed a...				J Nat Prod 79: 629-61 (2016) Article DOI: 10.1021/acs.jnatprod.5b01055 BindingDB Entry DOI: 10.7270/Q2W37Z73
NIH Special Volunteer Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%