Found 17 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50139137
(CHEMBL3759162)Show SMILES [Cl-].CCCCn1cc[n+](Cc2cc(=O)oc3cc(C)cc(C)c23)c1 Show InChI InChI=1S/C19H23N2O2.ClH/c1-4-5-6-20-7-8-21(13-20)12-16-11-18(22)23-17-10-14(2)9-15(3)19(16)17;/h7-11,13H,4-6,12H2,1-3H3;1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Competitive inhibition of human serum PON1 using paraoxon as substrate by Lineweaver-Burk plot analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM86068
(PPC)Show InChI InChI=1S/C16H12O4/c1-9-2-4-10(5-3-9)12-6-11-7-13(17)14(18)8-15(11)20-16(12)19/h2-8,17-18H,1H3 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50139137
(CHEMBL3759162)Show SMILES [Cl-].CCCCn1cc[n+](Cc2cc(=O)oc3cc(C)cc(C)c23)c1 Show InChI InChI=1S/C19H23N2O2.ClH/c1-4-5-6-20-7-8-21(13-20)12-16-11-18(22)23-17-10-14(2)9-15(3)19(16)17;/h7-11,13H,4-6,12H2,1-3H3;1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50144692
(CHEMBL3759251)Show SMILES [Cl-].O=C(C[n+]1cn(Cn2nnc3ccccc23)c2ccccc12)c1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C24H18N6O3.ClH/c31-22(16-9-10-23-18(11-16)25-24(32)13-33-23)12-28-14-29(21-8-4-3-7-20(21)28)15-30-19-6-2-1-5-17(19)26-27-30;/h1-11,14H,12-13,15H2;1H | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50144693
(CHEMBL3758983)Show InChI InChI=1S/C12H13N4.ClH/c1-15-6-7-16(9-15)8-12-13-10-4-2-3-5-11(10)14-12;/h2-7,9H,8H2,1H3,(H,13,14);1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50139133
(CHEMBL3759178)Show InChI InChI=1S/C12H11ClO2/c1-7-3-4-10-9(6-13)5-11(14)15-12(10)8(7)2/h3-5H,6H2,1-2H3 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50139135
(CHEMBL3759775)Show SMILES [Cl-].Cc1cc(C)c2c(C[n+]3ccn(C)c3)cc(=O)oc2c1 Show InChI InChI=1S/C16H17N2O2.ClH/c1-11-6-12(2)16-13(8-15(19)20-14(16)7-11)9-18-5-4-17(3)10-18;/h4-8,10H,9H2,1-3H3;1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50144739
(CHEMBL3759516)Show InChI InChI=1S/C15H19N4.ClH/c1-2-3-8-18-9-10-19(12-18)11-15-16-13-6-4-5-7-14(13)17-15;/h4-7,9-10,12H,2-3,8,11H2,1H3,(H,16,17);1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50139132
(CHEMBL1462074)Show InChI InChI=1S/C12H11ClO2/c1-7-3-8(2)12-9(6-13)5-11(14)15-10(12)4-7/h3-5H,6H2,1-2H3 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50139134
(CHEMBL3758686)Show InChI InChI=1S/C14H15ClO2/c1-14(2,3)10-4-5-12-11(7-10)9(8-15)6-13(16)17-12/h4-7H,8H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50144690
(CHEMBL3759001)Show SMILES [Cl-].Cc1ccc2c(C[n+]3cn(Cn4nnc5ccccc45)c4ccccc34)cc(=O)oc2c1C Show InChI InChI=1S/C26H22N5O2.ClH/c1-17-11-12-20-19(13-25(32)33-26(20)18(17)2)14-29-15-30(24-10-6-5-9-23(24)29)16-31-22-8-4-3-7-21(22)27-28-31;/h3-13,15H,14,16H2,1-2H3;1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.38E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50139136
(CHEMBL3759337)Show SMILES [Cl-].Cc1n(C)cc[n+]1Cc1cc(=O)oc2cc(C)cc(C)c12 Show InChI InChI=1S/C17H19N2O2.ClH/c1-11-7-12(2)17-14(9-16(20)21-15(17)8-11)10-19-6-5-18(4)13(19)3;/h5-9H,10H2,1-4H3;1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.17E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50144740
(CHEMBL3758357)Show InChI InChI=1S/C14H11N5/c1-3-7-13-11(5-1)15-9-18(13)10-19-14-8-4-2-6-12(14)16-17-19/h1-9H,10H2 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.64E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50144738
(CHEMBL3758838)Show InChI InChI=1S/C13H15N4.ClH/c1-10-16(2)7-8-17(10)9-13-14-11-5-3-4-6-12(11)15-13;/h3-8H,9H2,1-2H3,(H,14,15);1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.26E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50144691
(CHEMBL3759697)Show SMILES [Cl-].CC(C)(C)c1ccc2oc(=O)cc(C[n+]3cn(Cn4nnc5ccccc45)c4ccccc34)c2c1 Show InChI InChI=1S/C28H26N5O2.ClH/c1-28(2,3)20-12-13-26-21(15-20)19(14-27(34)35-26)16-31-17-32(25-11-7-6-10-24(25)31)18-33-23-9-5-4-8-22(23)29-30-33;/h4-15,17H,16,18H2,1-3H3;1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.27E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50144742
(CHEMBL3758332)Show SMILES [Cl-].C(n1c[n+](Cc2ccccc2)c2ccccc12)n1nnc2ccccc12 Show InChI InChI=1S/C21H18N5.ClH/c1-2-8-17(9-3-1)14-24-15-25(21-13-7-6-12-20(21)24)16-26-19-11-5-4-10-18(19)22-23-26;/h1-13,15H,14,16H2;1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.06E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM50144741
(CHEMBL3760112)Show InChI InChI=1S/C18H20N5.ClH/c1-2-3-12-21-13-22(18-11-7-6-10-17(18)21)14-23-16-9-5-4-8-15(16)19-20-23;/h4-11,13H,2-3,12,14H2,1H3;1H/q+1;/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.33E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University
Curated by ChEMBL
| Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 1392-401 (2016)
Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG |
More data for this Ligand-Target Pair | |