Affinity Data by PubMed id=26910725

PubMed code 26910725

Found 93 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161982 (CHEMBL3792690) Show SMILES Clc1cccc(c1)-c1ccc2CC(=O)NC(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161982 (CHEMBL3792690) Show SMILES Clc1cccc(c1)-c1ccc2CC(=O)NC(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162054 (CHEMBL3792834) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162054 (CHEMBL3792834) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161997 (CHEMBL3792519) Show SMILES Ic1cccc2CC(=O)NC(=O)c12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161973 (CHEMBL3792448) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161993 (CHEMBL3792475) Show SMILES OC(=O)c1ccc2CC(=O)NC(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161976 (CHEMBL3792608) Show SMILES COc1ccc(cc1F)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161973 (CHEMBL3792448) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161994 (CHEMBL3793011) Show SMILES FC(F)(F)c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161975 (CHEMBL3793616) Show SMILES Fc1ccc(cc1Cl)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161976 (CHEMBL3792608) Show SMILES COc1ccc(cc1F)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162055 (CHEMBL3793925) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161974 (CHEMBL3792897) Show SMILES Fc1ccc(c(F)c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161971 (CHEMBL3793413) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1nc2ccccc2s1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161993 (CHEMBL3792475) Show SMILES OC(=O)c1ccc2CC(=O)NC(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161975 (CHEMBL3793616) Show SMILES Fc1ccc(cc1Cl)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161967 (CHEMBL3794248) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161984 (CHEMBL3792520) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161974 (CHEMBL3792897) Show SMILES Fc1ccc(c(F)c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161984 (CHEMBL3792520) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161983 (CHEMBL3793043) Show SMILES Clc1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161983 (CHEMBL3793043) Show SMILES Clc1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161981 (CHEMBL3793872) Show SMILES Clc1ccc(cc1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161981 (CHEMBL3793872) Show SMILES Clc1ccc(cc1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161994 (CHEMBL3793011) Show SMILES FC(F)(F)c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161979 (CHEMBL3792592) Show SMILES Brc1ccc(cc1)-c1ccc2CC(=O)NC(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161997 (CHEMBL3792519) Show SMILES Ic1cccc2CC(=O)NC(=O)c12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161987 (CHEMBL3793467) Show SMILES Ic1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161987 (CHEMBL3793467) Show SMILES Ic1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161980 (CHEMBL3794044) Show SMILES Brc1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161980 (CHEMBL3794044) Show SMILES Brc1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161970 (CHEMBL3793669) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1cnc2ccccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161998 (CHEMBL3794340) Show SMILES Ic1ccc2CC(=O)NC(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162053 (CHEMBL3792917) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162050 (CHEMBL3793839) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161991 (CHEMBL3792752) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161988 (CHEMBL3793210) Show SMILES Brc1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162052 (CHEMBL3794550) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161968 (CHEMBL3794036) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162051 (CHEMBL3792890) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161971 (CHEMBL3793413) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1nc2ccccc2s1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161992 (CHEMBL3794329) Show SMILES O=C1Cc2ccc(cc2C(=O)N1)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162046 (CHEMBL3793509) Show SMILES Oc1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161966 (CHEMBL3792741) Show SMILES CCOC(=O)C1C(=O)NC(=O)c2ccc(Br)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162049 (CHEMBL3793974) Show SMILES Oc1ccc(cc1)-c1ccc2CC(=O)NC(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162047 (CHEMBL3794188) Show SMILES Oc1cccc(c1)-c1ccc2CC(=O)NC(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162044 (CHEMBL3793459) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1cccnc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161985 (CHEMBL3792845) Show SMILES NC(=O)c1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161977 (CHEMBL3794489) Show SMILES COc1ccc(OC)c(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162066 (CHEMBL3793606) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161995 (CHEMBL3793979) Show SMILES [O-][N+](=O)c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162065 (CHEMBL3793030) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162045 (CHEMBL3794268) Show SMILES O=C1Cc2ccc(cc2C(=O)N1)-c1cccnc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161986 (CHEMBL3793425) Show SMILES OC(=O)c1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161986 (CHEMBL3793425) Show SMILES OC(=O)c1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162044 (CHEMBL3793459) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1cccnc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162043 (CHEMBL3793861) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162050 (CHEMBL3793839) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162066 (CHEMBL3793606) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161991 (CHEMBL3792752) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50322995 (CHEMBL1210769 \| cid_349435 \| isoquinoline-1,3(2H,4...) Show SMILES O=C1Cc2ccccc2C(=O)N1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162048 (CHEMBL3793108) Show SMILES Oc1cccc(c1)-c1cccc2CC(=O)NC(=O)c12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162070 (CHEMBL3793154) Show SMILES OC(=O)c1ccc(cc1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162046 (CHEMBL3793509) Show SMILES Oc1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162067 (CHEMBL3794008) Show SMILES Nc1ccc(cc1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162058 (CHEMBL3794519) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161978 (CHEMBL3794517) Show SMILES COc1cccc(OC)c1-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161989 (CHEMBL3793399) Show SMILES Brc1cccc2C(=O)NC(=O)Cc12 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162067 (CHEMBL3794008) Show SMILES Nc1ccc(cc1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162069 (CHEMBL3792554) Show SMILES Nc1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161992 (CHEMBL3794329) Show SMILES O=C1Cc2ccc(cc2C(=O)N1)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162069 (CHEMBL3792554) Show SMILES Nc1cccc(c1)-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161972 (CHEMBL3793886) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162042 (CHEMBL1928097) Show SMILES ON1C(=O)Cc2ccc(cc2C1=O)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162068 (CHEMBL3793891) Show SMILES Nc1cccc(c1)-c1ccc2CC(=O)NC(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161970 (CHEMBL3793669) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1cnc2ccccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161969 (CHEMBL3792579) Show SMILES O=C1Cc2cc(Cc3ccccc3)ccc2C(=O)N1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50161990 (CHEMBL1928103) Show SMILES ON1C(=O)Cc2cc(ccc2C1=O)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single stranded oligonucleotide DNA containing 3'-phophotyrosine (N14Y) as sub...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50161991 (CHEMBL3792752) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single stranded oligonucleotide DNA containing 3'-phophotyrosine (N14Y) as sub...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161964 (CHEMBL3793391) Show SMILES Brc1ccc2C(=O)NC(=O)c3cccc1c23 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162071 (CHEMBL3793508) Show SMILES OC(=O)c1ccccc1-c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161963 (CHEMBL3794399) Show SMILES O=C1NC(=O)c2ccc(-c3ccco3)c3cccc1c23 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161996 (CHEMBL3792469) Show SMILES OC(=O)c1ccc2C(=O)NC(=O)Cc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162043 (CHEMBL3793861) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161960 (CHEMBL3794195) Show SMILES Nc1c2c(CC(=O)NC2=O)nn1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161961 (CHEMBL3793579) Show SMILES Nc1c2c(CC(=O)NC2=O)nn1-c1cccnc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161962 (CHEMBL3793241) Show SMILES Nc1c2c(CC(=O)NC2=O)nn1-c1ccc(F)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161990 (CHEMBL1928103) Show SMILES ON1C(=O)Cc2cc(ccc2C1=O)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50161991 (CHEMBL3792752) Show SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single stranded oligonucleotide DNA containing 3'-phophotyrosine (N14Y) as sub...				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161959 (CHEMBL3793472) Show SMILES CC(=O)Nc1c2c(CC(=O)NC2=O)nn1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50161965 (CHEMBL3793103) Show SMILES O=c1[nH]c2cc(ccc2c(=O)[nH]1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50162041 (CHEMBL3793523) Show SMILES O=C1Cc2c(cccc2C(=O)N1)-c1ccco1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay				J Med Chem 59: 2734-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01973 BindingDB Entry DOI: 10.7270/Q20P11XD
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%