Affinity Data by PubMed id=26927488

PubMed code 26927488

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50152675 (CHEMBL3780099) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of porcine tubulin polymerization by UV-Vis microplate reader analysis				Eur J Med Chem 112: 367-72 (2016) Article DOI: 10.1016/j.ejmech.2016.02.004 BindingDB Entry DOI: 10.7270/Q2ZK5JHD
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin beta chain (Sus scrofa)	BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of porcine tubulin polymerization by UV-Vis microplate reader analysis				Eur J Med Chem 112: 367-72 (2016) Article DOI: 10.1016/j.ejmech.2016.02.004 BindingDB Entry DOI: 10.7270/Q2ZK5JHD
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin beta chain (Sus scrofa)	BDBM50152676 (CHEMBL3780828) Show SMILES COc1ccc(CNc2c(nc3ccccn23)-c2ccccc2O)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of porcine tubulin polymerization by UV-Vis microplate reader analysis				Eur J Med Chem 112: 367-72 (2016) Article DOI: 10.1016/j.ejmech.2016.02.004 BindingDB Entry DOI: 10.7270/Q2ZK5JHD
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta chain (Sus scrofa)	BDBM50152677 (CHEMBL3780715) Show SMILES COc1ccc(CNc2c(nc3cnccn23)-c2ccccc2O)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of porcine tubulin polymerization by UV-Vis microplate reader analysis				Eur J Med Chem 112: 367-72 (2016) Article DOI: 10.1016/j.ejmech.2016.02.004 BindingDB Entry DOI: 10.7270/Q2ZK5JHD
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%