Affinity Data by PubMed id=2704032

PubMed code 2704032

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004734 (CHEMBL310852 \| N-Methyl-N-(1-methyl-4-pyrrolidin-1...) Show SMILES CC(C#CCN1CCCC1)N(C)C(C)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic receptor in the rat cerebral cortex.				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50228071 (CHEMBL110892) Show SMILES CC(=O)N1CCCC1C#CCN1CCCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic receptor in the rat cerebral cortex.				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50228070 (CHEMBL354685) Show SMILES CC(=O)N1C(CCC1=O)C#CCN1CCCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic acetylcholine receptor in the rat cerebra...				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50228064 (CHEMBL169112) Show SMILES [I-].CC(=O)N1CCCC1C#CC[N+](C)(C)C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic acetylcholine receptor in the rat cerebra...				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50228066 (CHEMBL354983) Show SMILES [I-].CC(=O)N1C(CCC1=O)C#CC[N+](C)(C)C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic acetylcholine receptor in the rat cerebra...				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50228065 (CHEMBL169456) Show SMILES CN1C(CCC1=O)C#CCN1CCCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic receptor in the rat cerebral cortex.				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50228087 (CHEMBL323032) Show SMILES CN(C)CC#CC1CCCN1C(C)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.54E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic receptor in the rat cerebral cortex				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50228067 (CHEMBL424383) Show SMILES CN(C)CC#CC1CCC(=O)N1C(C)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.32E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic acetylcholine receptor in the rat cerebra...				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50228068 (CHEMBL169850) Show SMILES [I-].CN1C(CCC1=O)C#CC[N+](C)(C)C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.45E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic acetylcholine receptor in the rat cerebra...				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50228069 (CHEMBL167892) Show SMILES CN(C)CC#CC1CCC(=O)N1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.04E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Compound was tested for the concentration that inhibited the specific binding of (-)-[3H]-NMS to muscarinic acetylcholine receptor in the rat cerebra...				J Med Chem 32: 863-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ63RP
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%