Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50173334 (CHEMBL3809935) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of His-tagged human recombinant cKIT expressed in baculovirus using Tyr 06 peptide as substrate after 1 hr by Z-lyte assay | J Med Chem 59: 3964-79 (2016) Article DOI: 10.1021/acs.jmedchem.6b00200 BindingDB Entry DOI: 10.7270/Q25D8TR4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM50173334 (CHEMBL3809935) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal GST-tagged recombinant human PDGFRbeta (amino acids 557-end) expressed in baculovirus infected insect Sf9 cells using Poly(4... | J Med Chem 59: 3964-79 (2016) Article DOI: 10.1021/acs.jmedchem.6b00200 BindingDB Entry DOI: 10.7270/Q25D8TR4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM50173334 (CHEMBL3809935) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of GST-tagged human DDR1 expressed in baculovirus after 1 hr by Z-lyte assay | J Med Chem 59: 3964-79 (2016) Article DOI: 10.1021/acs.jmedchem.6b00200 BindingDB Entry DOI: 10.7270/Q25D8TR4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM50173334 (CHEMBL3809935) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 133 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of His-tagged recombinant human CSF1R expressed in baculovirus expression system after 1 hr by Z-lyte assay | J Med Chem 59: 3964-79 (2016) Article DOI: 10.1021/acs.jmedchem.6b00200 BindingDB Entry DOI: 10.7270/Q25D8TR4 | |||||||||||
More data for this Ligand-Target Pair |