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PubMed code 27137360

Compile data set for download or QSAR
Found 100 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171191
PNG
(CHEMBL3806054)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H18ClFN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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0.540n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171190
PNG
(CHEMBL3804902)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H19FN6O4S2/c29-20-7-5-17(6-8-20)26-19(15-35(34-26)21-9-11-22(12-10-21)41(30,37)38)14-31-33-28-32-24(16-40-28)23-13-18-3-1-2-4-25(18)39-27(23)36/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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0.540n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171193
PNG
(CHEMBL3805892)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H19ClN6O4S2/c29-20-7-5-17(6-8-20)26-19(15-35(34-26)21-9-11-22(12-10-21)41(30,37)38)14-31-33-28-32-24(16-40-28)23-13-18-3-1-2-4-25(18)39-27(23)36/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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0.610n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171206
PNG
(CHEMBL3805919)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2cc(Br)ccc2oc1=O
Show InChI InChI=1S/C17H14BrN3O4S/c1-10(20-21-13-3-5-14(6-4-13)26(19,23)24)15-9-11-8-12(18)2-7-16(11)25-17(15)22/h2-9,21H,1H3,(H2,19,23,24)/b20-10+
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0.620n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171205
PNG
(CHEMBL3805906)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2cc(Cl)ccc2oc1=O
Show InChI InChI=1S/C17H14ClN3O4S/c1-10(20-21-13-3-5-14(6-4-13)26(19,23)24)15-9-11-8-12(18)2-7-16(11)25-17(15)22/h2-9,21H,1H3,(H2,19,23,24)/b20-10+
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0.660n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171200
PNG
(CHEMBL2316107)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2cc(Cl)ccc2oc1=O
Show InChI InChI=1S/C18H10ClN3O4S2/c19-10-1-4-15-9(5-10)6-12(17(23)26-15)13-8-22-14-3-2-11(28(20,24)25)7-16(14)27-18(22)21-13/h1-8H,(H2,20,24,25)
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0.680n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171199
PNG
(CHEMBL2316106)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2ccccc2oc1=O
Show InChI InChI=1S/C18H11N3O4S2/c19-27(23,24)11-5-6-14-16(8-11)26-18-20-13(9-21(14)18)12-7-10-3-1-2-4-15(10)25-17(12)22/h1-9H,(H2,19,23,24)
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2.20n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171193
PNG
(CHEMBL3805892)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H19ClN6O4S2/c29-20-7-5-17(6-8-20)26-19(15-35(34-26)21-9-11-22(12-10-21)41(30,37)38)14-31-33-28-32-24(16-40-28)23-13-18-3-1-2-4-25(18)39-27(23)36/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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2.30n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171190
PNG
(CHEMBL3804902)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H19FN6O4S2/c29-20-7-5-17(6-8-20)26-19(15-35(34-26)21-9-11-22(12-10-21)41(30,37)38)14-31-33-28-32-24(16-40-28)23-13-18-3-1-2-4-25(18)39-27(23)36/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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2.30n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171205
PNG
(CHEMBL3805906)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2cc(Cl)ccc2oc1=O
Show InChI InChI=1S/C17H14ClN3O4S/c1-10(20-21-13-3-5-14(6-4-13)26(19,23)24)15-9-11-8-12(18)2-7-16(11)25-17(15)22/h2-9,21H,1H3,(H2,19,23,24)/b20-10+
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2.40n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171191
PNG
(CHEMBL3806054)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H18ClFN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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2.5n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171188
PNG
(CHEMBL3805601)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H19ClN6O4S2/c29-20-6-11-25-18(12-20)13-23(27(36)39-25)24-16-40-28(32-24)33-31-14-19-15-35(34-26(19)17-4-2-1-3-5-17)21-7-9-22(10-8-21)41(30,37)38/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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2.5n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171194
PNG
(CHEMBL3805886)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H18Cl2N6O4S2/c29-19-3-1-16(2-4-19)26-18(14-36(35-26)21-6-8-22(9-7-21)42(31,38)39)13-32-34-28-33-24(15-41-28)23-12-17-11-20(30)5-10-25(17)40-27(23)37/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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3.20n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171184
PNG
(CHEMBL3806010)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Br)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21BrN6O4S2/c1-17-2-4-18(5-3-17)27-20(15-36(35-27)22-7-9-23(10-8-22)42(31,38)39)14-32-34-29-33-25(16-41-29)24-13-19-12-21(30)6-11-26(19)40-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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3.30n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171195
PNG
(CHEMBL3806068)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H18BrClN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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3.40n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171201
PNG
(CHEMBL2316108)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2cc(Br)ccc2oc1=O
Show InChI InChI=1S/C18H10BrN3O4S2/c19-10-1-4-15-9(5-10)6-12(17(23)26-15)13-8-22-14-3-2-11(28(20,24)25)7-16(14)27-18(22)21-13/h1-8H,(H2,20,24,25)
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3.5n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171197
PNG
(CHEMBL3805418)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)cc1
Show InChI InChI=1S/C18H12ClN3O4S2/c19-11-1-6-16-10(7-11)8-14(17(23)26-16)15-9-27-18(22-15)21-12-2-4-13(5-3-12)28(20,24)25/h1-9H,(H,21,22)(H2,20,24,25)
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3.90n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171183
PNG
(CHEMBL3805723)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2ccccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H22N6O5S2/c1-39-22-10-6-18(7-11-22)27-20(16-35(34-27)21-8-12-23(13-9-21)42(30,37)38)15-31-33-29-32-25(17-41-29)24-14-19-4-2-3-5-26(19)40-28(24)36/h2-17H,1H3,(H,32,33)(H2,30,37,38)/b31-15-
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4.20n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171202
PNG
(CHEMBL3805222)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C17H15N3O4S/c1-11(15-10-12-4-2-3-5-16(12)24-17(15)21)19-20-13-6-8-14(9-7-13)25(18,22)23/h2-10,20H,1H3,(H2,18,22,23)/b19-11+
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4.40n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171192
PNG
(CHEMBL3804909)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H18BrFN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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5.5n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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5.70n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171189
PNG
(CHEMBL3805263)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H20N6O4S2/c29-40(36,37)22-12-10-21(11-13-22)34-16-20(26(33-34)18-6-2-1-3-7-18)15-30-32-28-31-24(17-39-28)23-14-19-8-4-5-9-25(19)38-27(23)35/h1-17H,(H,31,32)(H2,29,36,37)/b30-15-
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5.90n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171198
PNG
(CHEMBL3804869)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)cc1
Show InChI InChI=1S/C18H12BrN3O4S2/c19-11-1-6-16-10(7-11)8-14(17(23)26-16)15-9-27-18(22-15)21-12-2-4-13(5-3-12)28(20,24)25/h1-9H,(H,21,22)(H2,20,24,25)
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6.30n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171200
PNG
(CHEMBL2316107)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2cc(Cl)ccc2oc1=O
Show InChI InChI=1S/C18H10ClN3O4S2/c19-10-1-4-15-9(5-10)6-12(17(23)26-15)13-8-22-14-3-2-11(28(20,24)25)7-16(14)27-18(22)21-13/h1-8H,(H2,20,24,25)
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11n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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12n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171185
PNG
(CHEMBL3805133)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Cl)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21ClN6O4S2/c1-17-2-4-18(5-3-17)27-20(15-36(35-27)22-7-9-23(10-8-22)42(31,38)39)14-32-34-29-33-25(16-41-29)24-13-19-12-21(30)6-11-26(19)40-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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13n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171202
PNG
(CHEMBL3805222)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C17H15N3O4S/c1-11(15-10-12-4-2-3-5-16(12)24-17(15)21)19-20-13-6-8-14(9-7-13)25(18,22)23/h2-10,20H,1H3,(H2,18,22,23)/b19-11+
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13n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171187
PNG
(CHEMBL3804879)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H19BrN6O4S2/c29-20-6-11-25-18(12-20)13-23(27(36)39-25)24-16-40-28(32-24)33-31-14-19-15-35(34-26(19)17-4-2-1-3-5-17)21-7-9-22(10-8-21)41(30,37)38/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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14n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171196
PNG
(CHEMBL3805861)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3ccccc3oc2=O)cc1
Show InChI InChI=1S/C18H13N3O4S2/c19-27(23,24)13-7-5-12(6-8-13)20-18-21-15(10-26-18)14-9-11-3-1-2-4-16(11)25-17(14)22/h1-10H,(H,20,21)(H2,19,23,24)
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15n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171193
PNG
(CHEMBL3805892)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H19ClN6O4S2/c29-20-7-5-17(6-8-20)26-19(15-35(34-26)21-9-11-22(12-10-21)41(30,37)38)14-31-33-28-32-24(16-40-28)23-13-18-3-1-2-4-25(18)39-27(23)36/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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16n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171181
PNG
(CHEMBL3806081)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Br)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21BrN6O5S2/c1-40-22-7-2-17(3-8-22)27-19(15-36(35-27)21-5-9-23(10-6-21)43(31,38)39)14-32-34-29-33-25(16-42-29)24-13-18-12-20(30)4-11-26(18)41-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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17n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171183
PNG
(CHEMBL3805723)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2ccccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H22N6O5S2/c1-39-22-10-6-18(7-11-22)27-20(16-35(34-27)21-8-12-23(13-9-21)42(30,37)38)15-31-33-29-32-25(17-41-29)24-14-19-4-2-3-5-26(19)40-28(24)36/h2-17H,1H3,(H,32,33)(H2,30,37,38)/b31-15-
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17n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171184
PNG
(CHEMBL3806010)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Br)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21BrN6O4S2/c1-17-2-4-18(5-3-17)27-20(15-36(35-27)22-7-9-23(10-8-22)42(31,38)39)14-32-34-29-33-25(16-41-29)24-13-19-12-21(30)6-11-26(19)40-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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17n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171191
PNG
(CHEMBL3806054)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H18ClFN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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17n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171192
PNG
(CHEMBL3804909)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H18BrFN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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18n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171186
PNG
(CHEMBL3805080)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2ccccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H22N6O4S2/c1-18-6-8-19(9-7-18)27-21(16-35(34-27)22-10-12-23(13-11-22)41(30,37)38)15-31-33-29-32-25(17-40-29)24-14-20-4-2-3-5-26(20)39-28(24)36/h2-17H,1H3,(H,32,33)(H2,30,37,38)/b31-15-
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19n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171182
PNG
(CHEMBL3805545)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Cl)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21ClN6O5S2/c1-40-22-7-2-17(3-8-22)27-19(15-36(35-27)21-5-9-23(10-6-21)43(31,38)39)14-32-34-29-33-25(16-42-29)24-13-18-12-20(30)4-11-26(18)41-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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19n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171189
PNG
(CHEMBL3805263)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H20N6O4S2/c29-40(36,37)22-12-10-21(11-13-22)34-16-20(26(33-34)18-6-2-1-3-7-18)15-30-32-28-31-24(17-39-28)23-14-19-8-4-5-9-25(19)38-27(23)35/h1-17H,(H,31,32)(H2,29,36,37)/b30-15-
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20n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171182
PNG
(CHEMBL3805545)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Cl)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21ClN6O5S2/c1-40-22-7-2-17(3-8-22)27-19(15-36(35-27)21-5-9-23(10-6-21)43(31,38)39)14-32-34-29-33-25(16-42-29)24-13-18-12-20(30)4-11-26(18)41-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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20n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171181
PNG
(CHEMBL3806081)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Br)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21BrN6O5S2/c1-40-22-7-2-17(3-8-22)27-19(15-36(35-27)21-5-9-23(10-6-21)43(31,38)39)14-32-34-29-33-25(16-42-29)24-13-18-12-20(30)4-11-26(18)41-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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20n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171190
PNG
(CHEMBL3804902)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H19FN6O4S2/c29-20-7-5-17(6-8-20)26-19(15-35(34-26)21-9-11-22(12-10-21)41(30,37)38)14-31-33-28-32-24(16-40-28)23-13-18-3-1-2-4-25(18)39-27(23)36/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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21n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171206
PNG
(CHEMBL3805919)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2cc(Br)ccc2oc1=O
Show InChI InChI=1S/C17H14BrN3O4S/c1-10(20-21-13-3-5-14(6-4-13)26(19,23)24)15-9-11-8-12(18)2-7-16(11)25-17(15)22/h2-9,21H,1H3,(H2,19,23,24)/b20-10+
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22n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171187
PNG
(CHEMBL3804879)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H19BrN6O4S2/c29-20-6-11-25-18(12-20)13-23(27(36)39-25)24-16-40-28(32-24)33-31-14-19-15-35(34-26(19)17-4-2-1-3-5-17)21-7-9-22(10-8-21)41(30,37)38/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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22n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171183
PNG
(CHEMBL3805723)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2ccccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H22N6O5S2/c1-39-22-10-6-18(7-11-22)27-20(16-35(34-27)21-8-12-23(13-9-21)42(30,37)38)15-31-33-29-32-25(17-41-29)24-14-19-4-2-3-5-26(19)40-28(24)36/h2-17H,1H3,(H,32,33)(H2,30,37,38)/b31-15-
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22n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171200
PNG
(CHEMBL2316107)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2cc(Cl)ccc2oc1=O
Show InChI InChI=1S/C18H10ClN3O4S2/c19-10-1-4-15-9(5-10)6-12(17(23)26-15)13-8-22-14-3-2-11(28(20,24)25)7-16(14)27-18(22)21-13/h1-8H,(H2,20,24,25)
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23n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171205
PNG
(CHEMBL3805906)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2cc(Cl)ccc2oc1=O
Show InChI InChI=1S/C17H14ClN3O4S/c1-10(20-21-13-3-5-14(6-4-13)26(19,23)24)15-9-11-8-12(18)2-7-16(11)25-17(15)22/h2-9,21H,1H3,(H2,19,23,24)/b20-10+
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23n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171195
PNG
(CHEMBL3806068)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H18BrClN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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23n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171206
PNG
(CHEMBL3805919)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2cc(Br)ccc2oc1=O
Show InChI InChI=1S/C17H14BrN3O4S/c1-10(20-21-13-3-5-14(6-4-13)26(19,23)24)15-9-11-8-12(18)2-7-16(11)25-17(15)22/h2-9,21H,1H3,(H2,19,23,24)/b20-10+
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24n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171185
PNG
(CHEMBL3805133)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Cl)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21ClN6O4S2/c1-17-2-4-18(5-3-17)27-20(15-36(35-27)22-7-9-23(10-8-22)42(31,38)39)14-32-34-29-33-25(16-41-29)24-13-19-12-21(30)6-11-26(19)40-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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24n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171196
PNG
(CHEMBL3805861)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3ccccc3oc2=O)cc1
Show InChI InChI=1S/C18H13N3O4S2/c19-27(23,24)13-7-5-12(6-8-13)20-18-21-15(10-26-18)14-9-11-3-1-2-4-16(11)25-17(14)22/h1-10H,(H,20,21)(H2,19,23,24)
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24n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171198
PNG
(CHEMBL3804869)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)cc1
Show InChI InChI=1S/C18H12BrN3O4S2/c19-11-1-6-16-10(7-11)8-14(17(23)26-16)15-9-27-18(22-15)21-12-2-4-13(5-3-12)28(20,24)25/h1-9H,(H,21,22)(H2,20,24,25)
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24n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171201
PNG
(CHEMBL2316108)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2cc(Br)ccc2oc1=O
Show InChI InChI=1S/C18H10BrN3O4S2/c19-10-1-4-15-9(5-10)6-12(17(23)26-15)13-8-22-14-3-2-11(28(20,24)25)7-16(14)27-18(22)21-13/h1-8H,(H2,20,24,25)
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25n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171197
PNG
(CHEMBL3805418)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)cc1
Show InChI InChI=1S/C18H12ClN3O4S2/c19-11-1-6-16-10(7-11)8-14(17(23)26-16)15-9-27-18(22-15)21-12-2-4-13(5-3-12)28(20,24)25/h1-9H,(H,21,22)(H2,20,24,25)
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25n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171182
PNG
(CHEMBL3805545)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Cl)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21ClN6O5S2/c1-40-22-7-2-17(3-8-22)27-19(15-36(35-27)21-5-9-23(10-6-21)43(31,38)39)14-32-34-29-33-25(16-42-29)24-13-18-12-20(30)4-11-26(18)41-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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25n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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25n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171184
PNG
(CHEMBL3806010)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Br)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21BrN6O4S2/c1-17-2-4-18(5-3-17)27-20(15-36(35-27)22-7-9-23(10-8-22)42(31,38)39)14-32-34-29-33-25(16-41-29)24-13-19-12-21(30)6-11-26(19)40-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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26n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171192
PNG
(CHEMBL3804909)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H18BrFN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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27n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171194
PNG
(CHEMBL3805886)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H18Cl2N6O4S2/c29-19-3-1-16(2-4-19)26-18(14-36(35-26)21-6-8-22(9-7-21)42(31,38)39)13-32-34-28-33-24(15-41-28)23-12-17-11-20(30)5-10-25(17)40-27(23)37/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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28n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171188
PNG
(CHEMBL3805601)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H19ClN6O4S2/c29-20-6-11-25-18(12-20)13-23(27(36)39-25)24-16-40-28(32-24)33-31-14-19-15-35(34-26(19)17-4-2-1-3-5-17)21-7-9-22(10-8-21)41(30,37)38/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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28n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171186
PNG
(CHEMBL3805080)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2ccccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H22N6O4S2/c1-18-6-8-19(9-7-18)27-21(16-35(34-27)22-10-12-23(13-11-22)41(30,37)38)15-31-33-29-32-25(17-40-29)24-14-20-4-2-3-5-26(20)39-28(24)36/h2-17H,1H3,(H,32,33)(H2,30,37,38)/b31-15-
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29n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171193
PNG
(CHEMBL3805892)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H19ClN6O4S2/c29-20-7-5-17(6-8-20)26-19(15-35(34-26)21-9-11-22(12-10-21)41(30,37)38)14-31-33-28-32-24(16-40-28)23-13-18-3-1-2-4-25(18)39-27(23)36/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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30n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171181
PNG
(CHEMBL3806081)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Br)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21BrN6O5S2/c1-40-22-7-2-17(3-8-22)27-19(15-36(35-27)21-5-9-23(10-6-21)43(31,38)39)14-32-34-29-33-25(16-42-29)24-13-18-12-20(30)4-11-26(18)41-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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38n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171199
PNG
(CHEMBL2316106)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2ccccc2oc1=O
Show InChI InChI=1S/C18H11N3O4S2/c19-27(23,24)11-5-6-14-16(8-11)26-18-20-13(9-21(14)18)12-7-10-3-1-2-4-15(10)25-17(12)22/h1-9H,(H2,19,23,24)
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44n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171185
PNG
(CHEMBL3805133)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Cl)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21ClN6O4S2/c1-17-2-4-18(5-3-17)27-20(15-36(35-27)22-7-9-23(10-8-22)42(31,38)39)14-32-34-29-33-25(16-41-29)24-13-19-12-21(30)6-11-26(19)40-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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49n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50171186
PNG
(CHEMBL3805080)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2ccccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H22N6O4S2/c1-18-6-8-19(9-7-18)27-21(16-35(34-27)22-10-12-23(13-11-22)41(30,37)38)15-31-33-29-32-25(17-40-29)24-14-20-4-2-3-5-26(20)39-28(24)36/h2-17H,1H3,(H,32,33)(H2,30,37,38)/b31-15-
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55n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50171202
PNG
(CHEMBL3805222)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C17H15N3O4S/c1-11(15-10-12-4-2-3-5-16(12)24-17(15)21)19-20-13-6-8-14(9-7-13)25(18,22)23/h2-10,20H,1H3,(H2,18,22,23)/b19-11+
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59n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 9 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171195
PNG
(CHEMBL3806068)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H18BrClN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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62n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171194
PNG
(CHEMBL3805886)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H18Cl2N6O4S2/c29-19-3-1-16(2-4-19)26-18(14-36(35-26)21-6-8-22(9-7-21)42(31,38)39)13-32-34-28-33-24(15-41-28)23-12-17-11-20(30)5-10-25(17)40-27(23)37/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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96n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171201
PNG
(CHEMBL2316108)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2cc(Br)ccc2oc1=O
Show InChI InChI=1S/C18H10BrN3O4S2/c19-10-1-4-15-9(5-10)6-12(17(23)26-15)13-8-22-14-3-2-11(28(20,24)25)7-16(14)27-18(22)21-13/h1-8H,(H2,20,24,25)
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105n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171188
PNG
(CHEMBL3805601)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H19ClN6O4S2/c29-20-6-11-25-18(12-20)13-23(27(36)39-25)24-16-40-28(32-24)33-31-14-19-15-35(34-26(19)17-4-2-1-3-5-17)21-7-9-22(10-8-21)41(30,37)38/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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106n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171189
PNG
(CHEMBL3805263)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H20N6O4S2/c29-40(36,37)22-12-10-21(11-13-22)34-16-20(26(33-34)18-6-2-1-3-7-18)15-30-32-28-31-24(17-39-28)23-14-19-8-4-5-9-25(19)38-27(23)35/h1-17H,(H,31,32)(H2,29,36,37)/b30-15-
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153n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171187
PNG
(CHEMBL3804879)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H19BrN6O4S2/c29-20-6-11-25-18(12-20)13-23(27(36)39-25)24-16-40-28(32-24)33-31-14-19-15-35(34-26(19)17-4-2-1-3-5-17)21-7-9-22(10-8-21)41(30,37)38/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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154n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171199
PNG
(CHEMBL2316106)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2ccccc2oc1=O
Show InChI InChI=1S/C18H11N3O4S2/c19-27(23,24)11-5-6-14-16(8-11)26-18-20-13(9-21(14)18)12-7-10-3-1-2-4-15(10)25-17(12)22/h1-9H,(H2,19,23,24)
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214n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171202
PNG
(CHEMBL3805222)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C17H15N3O4S/c1-11(15-10-12-4-2-3-5-16(12)24-17(15)21)19-20-13-6-8-14(9-7-13)25(18,22)23/h2-10,20H,1H3,(H2,18,22,23)/b19-11+
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220n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171199
PNG
(CHEMBL2316106)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2ccccc2oc1=O
Show InChI InChI=1S/C18H11N3O4S2/c19-27(23,24)11-5-6-14-16(8-11)26-18-20-13(9-21(14)18)12-7-10-3-1-2-4-15(10)25-17(12)22/h1-9H,(H2,19,23,24)
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222n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171201
PNG
(CHEMBL2316108)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2cc(Br)ccc2oc1=O
Show InChI InChI=1S/C18H10BrN3O4S2/c19-10-1-4-15-9(5-10)6-12(17(23)26-15)13-8-22-14-3-2-11(28(20,24)25)7-16(14)27-18(22)21-13/h1-8H,(H2,20,24,25)
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226n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171198
PNG
(CHEMBL3804869)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)cc1
Show InChI InChI=1S/C18H12BrN3O4S2/c19-11-1-6-16-10(7-11)8-14(17(23)26-16)15-9-27-18(22-15)21-12-2-4-13(5-3-12)28(20,24)25/h1-9H,(H,21,22)(H2,20,24,25)
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247n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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250n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171190
PNG
(CHEMBL3804902)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H19FN6O4S2/c29-20-7-5-17(6-8-20)26-19(15-35(34-26)21-9-11-22(12-10-21)41(30,37)38)14-31-33-28-32-24(16-40-28)23-13-18-3-1-2-4-25(18)39-27(23)36/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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263n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171181
PNG
(CHEMBL3806081)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Br)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21BrN6O5S2/c1-40-22-7-2-17(3-8-22)27-19(15-36(35-27)21-5-9-23(10-6-21)43(31,38)39)14-32-34-29-33-25(16-42-29)24-13-18-12-20(30)4-11-26(18)41-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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273n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171184
PNG
(CHEMBL3806010)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Br)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21BrN6O4S2/c1-17-2-4-18(5-3-17)27-20(15-36(35-27)22-7-9-23(10-8-22)42(31,38)39)14-32-34-29-33-25(16-41-29)24-13-19-12-21(30)6-11-26(19)40-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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273n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171196
PNG
(CHEMBL3805861)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3ccccc3oc2=O)cc1
Show InChI InChI=1S/C18H13N3O4S2/c19-27(23,24)13-7-5-12(6-8-13)20-18-21-15(10-26-18)14-9-11-3-1-2-4-16(11)25-17(14)22/h1-10H,(H,20,21)(H2,19,23,24)
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292n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171186
PNG
(CHEMBL3805080)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2ccccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H22N6O4S2/c1-18-6-8-19(9-7-18)27-21(16-35(34-27)22-10-12-23(13-11-22)41(30,37)38)15-31-33-29-32-25(17-40-29)24-14-20-4-2-3-5-26(20)39-28(24)36/h2-17H,1H3,(H,32,33)(H2,30,37,38)/b31-15-
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296n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171187
PNG
(CHEMBL3804879)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H19BrN6O4S2/c29-20-6-11-25-18(12-20)13-23(27(36)39-25)24-16-40-28(32-24)33-31-14-19-15-35(34-26(19)17-4-2-1-3-5-17)21-7-9-22(10-8-21)41(30,37)38/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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300n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171183
PNG
(CHEMBL3805723)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2ccccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H22N6O5S2/c1-39-22-10-6-18(7-11-22)27-20(16-35(34-27)21-8-12-23(13-9-21)42(30,37)38)15-31-33-29-32-25(17-41-29)24-14-19-4-2-3-5-26(19)40-28(24)36/h2-17H,1H3,(H,32,33)(H2,30,37,38)/b31-15-
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310n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171182
PNG
(CHEMBL3805545)
Show SMILES COc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Cl)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21ClN6O5S2/c1-40-22-7-2-17(3-8-22)27-19(15-36(35-27)21-5-9-23(10-6-21)43(31,38)39)14-32-34-29-33-25(16-42-29)24-13-18-12-20(30)4-11-26(18)41-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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315n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171196
PNG
(CHEMBL3805861)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3ccccc3oc2=O)cc1
Show InChI InChI=1S/C18H13N3O4S2/c19-27(23,24)13-7-5-12(6-8-13)20-18-21-15(10-26-18)14-9-11-3-1-2-4-16(11)25-17(14)22/h1-10H,(H,20,21)(H2,19,23,24)
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341n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171191
PNG
(CHEMBL3806054)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H18ClFN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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350n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171189
PNG
(CHEMBL3805263)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3ccccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H20N6O4S2/c29-40(36,37)22-12-10-21(11-13-22)34-16-20(26(33-34)18-6-2-1-3-7-18)15-30-32-28-31-24(17-39-28)23-14-19-8-4-5-9-25(19)38-27(23)35/h1-17H,(H,31,32)(H2,29,36,37)/b30-15-
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368n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171205
PNG
(CHEMBL3805906)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2cc(Cl)ccc2oc1=O
Show InChI InChI=1S/C17H14ClN3O4S/c1-10(20-21-13-3-5-14(6-4-13)26(19,23)24)15-9-11-8-12(18)2-7-16(11)25-17(15)22/h2-9,21H,1H3,(H2,19,23,24)/b20-10+
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758n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171188
PNG
(CHEMBL3805601)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccccc1
Show InChI InChI=1S/C28H19ClN6O4S2/c29-20-6-11-25-18(12-20)13-23(27(36)39-25)24-16-40-28(32-24)33-31-14-19-15-35(34-26(19)17-4-2-1-3-5-17)21-7-9-22(10-8-21)41(30,37)38/h1-16H,(H,32,33)(H2,30,37,38)/b31-14-
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862n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171198
PNG
(CHEMBL3804869)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)cc1
Show InChI InChI=1S/C18H12BrN3O4S2/c19-11-1-6-16-10(7-11)8-14(17(23)26-16)15-9-27-18(22-15)21-12-2-4-13(5-3-12)28(20,24)25/h1-9H,(H,21,22)(H2,20,24,25)
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1.15E+3n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171200
PNG
(CHEMBL2316107)
Show SMILES NS(=O)(=O)c1ccc2c(c1)sc1nc(cn21)-c1cc2cc(Cl)ccc2oc1=O
Show InChI InChI=1S/C18H10ClN3O4S2/c19-10-1-4-15-9(5-10)6-12(17(23)26-15)13-8-22-14-3-2-11(28(20,24)25)7-16(14)27-18(22)21-13/h1-8H,(H2,20,24,25)
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1.39E+3n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171192
PNG
(CHEMBL3804909)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H18BrFN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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1.46E+3n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171206
PNG
(CHEMBL3805919)
Show SMILES C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1cc2cc(Br)ccc2oc1=O
Show InChI InChI=1S/C17H14BrN3O4S/c1-10(20-21-13-3-5-14(6-4-13)26(19,23)24)15-9-11-8-12(18)2-7-16(11)25-17(15)22/h2-9,21H,1H3,(H2,19,23,24)/b20-10+
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1.75E+3n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50171197
PNG
(CHEMBL3805418)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)cc1
Show InChI InChI=1S/C18H12ClN3O4S2/c19-11-1-6-16-10(7-11)8-14(17(23)26-16)15-9-27-18(22-15)21-12-2-4-13(5-3-12)28(20,24)25/h1-9H,(H,21,22)(H2,20,24,25)
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1.87E+3n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171197
PNG
(CHEMBL3805418)
Show SMILES NS(=O)(=O)c1ccc(Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)cc1
Show InChI InChI=1S/C18H12ClN3O4S2/c19-11-1-6-16-10(7-11)8-14(17(23)26-16)15-9-27-18(22-15)21-12-2-4-13(5-3-12)28(20,24)25/h1-9H,(H,21,22)(H2,20,24,25)
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1.90E+3n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171194
PNG
(CHEMBL3805886)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Cl)ccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H18Cl2N6O4S2/c29-19-3-1-16(2-4-19)26-18(14-36(35-26)21-6-8-22(9-7-21)42(31,38)39)13-32-34-28-33-24(15-41-28)23-12-17-11-20(30)5-10-25(17)40-27(23)37/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
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2.00E+3n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171185
PNG
(CHEMBL3805133)
Show SMILES Cc1ccc(cc1)-c1nn(cc1\C=N/Nc1nc(cs1)-c1cc2cc(Cl)ccc2oc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H21ClN6O4S2/c1-17-2-4-18(5-3-17)27-20(15-36(35-27)22-7-9-23(10-8-22)42(31,38)39)14-32-34-29-33-25(16-41-29)24-13-19-12-21(30)6-11-26(19)40-28(24)37/h2-16H,1H3,(H,33,34)(H2,31,38,39)/b32-14-
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UniChem
PubMed
3.11E+3n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50171195
PNG
(CHEMBL3806068)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(\C=N/Nc2nc(cs2)-c2cc3cc(Br)ccc3oc2=O)c(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H18BrClN6O4S2/c29-19-3-10-25-17(11-19)12-23(27(37)40-25)24-15-41-28(33-24)34-32-13-18-14-36(21-6-8-22(9-7-21)42(31,38)39)35-26(18)16-1-4-20(30)5-2-16/h1-15H,(H,33,34)(H2,31,38,39)/b32-13-
PDB
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PC sid
UniChem
PubMed
3.23E+3n/an/an/an/an/an/an/an/a



Kurukshetra University

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assay


Bioorg Med Chem 24: 2882-2886 (2016)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%