Affinity Data by PubMed id=27140727

PubMed code 27140727

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Urease subunit alpha (Bacillus pasteurii)	BDBM181105 (3-(3,4,5-Trimethoxybenzoyl)-(4-hydroxycoumarin) (9...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a	n/a	30
COMSATS Institute of Information Technology					Assay Description Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 �L of buffers containing 100 mMol urea were incubated with 5 �L...				Bioorg Chem 66: 111-6 (2016) Article DOI: 10.1016/j.bioorg.2016.04.005 BindingDB Entry DOI: 10.7270/Q2QZ28RQ
COMSATS Institute of Information Technology					More data for this Ligand-Target Pair
Urease subunit alpha (Bacillus pasteurii)	BDBM181103 (3-Decanoyl-(4-hydroxycoumarin) (5)) Show SMILES CCCCCCCCCC(=O)c1c(O)c2ccccc2oc1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	30
COMSATS Institute of Information Technology					Assay Description Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 �L of buffers containing 100 mMol urea were incubated with 5 �L...				Bioorg Chem 66: 111-6 (2016) Article DOI: 10.1016/j.bioorg.2016.04.005 BindingDB Entry DOI: 10.7270/Q2QZ28RQ
COMSATS Institute of Information Technology					More data for this Ligand-Target Pair
Urease subunit alpha (Bacillus pasteurii)	BDBM181104 (3-Lauroyl-(4-hydroxycoumarin) (6)) Show SMILES CCCCCCCCCCCC(=O)c1c(O)c2ccccc2oc1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	30
COMSATS Institute of Information Technology					Assay Description Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 �L of buffers containing 100 mMol urea were incubated with 5 �L...				Bioorg Chem 66: 111-6 (2016) Article DOI: 10.1016/j.bioorg.2016.04.005 BindingDB Entry DOI: 10.7270/Q2QZ28RQ
COMSATS Institute of Information Technology					More data for this Ligand-Target Pair
Urease subunit alpha (Bacillus pasteurii)	BDBM50229993 (2-thiourea \| CHEMBL260876 \| Thiocarbamid \| Thiohar...) Show SMILES NC(N)=S Show InChI InChI=1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	30
COMSATS Institute of Information Technology					Assay Description Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 �L of buffers containing 100 mMol urea were incubated with 5 �L...				Bioorg Chem 66: 111-6 (2016) Article DOI: 10.1016/j.bioorg.2016.04.005 BindingDB Entry DOI: 10.7270/Q2QZ28RQ
COMSATS Institute of Information Technology					More data for this Ligand-Target Pair
Urease subunit alpha (Bacillus pasteurii)	BDBM181106 (3-(Methanesulfonoyl)-(4-hydroxycoumarin) (11)) Show SMILES CS(=O)(=O)c1c(O)c2ccccc2oc1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.95E+4	n/a	n/a	n/a	n/a	n/a	30
COMSATS Institute of Information Technology					Assay Description Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 �L of buffers containing 100 mMol urea were incubated with 5 �L...				Bioorg Chem 66: 111-6 (2016) Article DOI: 10.1016/j.bioorg.2016.04.005 BindingDB Entry DOI: 10.7270/Q2QZ28RQ
COMSATS Institute of Information Technology					More data for this Ligand-Target Pair
Urease subunit alpha (Bacillus pasteurii)	BDBM181102 (3-Nonanoyl-(4-hydroxycoumarin) (4)) Show SMILES CCCCCCCCC(=O)c1c(O)c2ccccc2oc1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.09E+4	n/a	n/a	n/a	n/a	n/a	30
COMSATS Institute of Information Technology					Assay Description Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 �L of buffers containing 100 mMol urea were incubated with 5 �L...				Bioorg Chem 66: 111-6 (2016) Article DOI: 10.1016/j.bioorg.2016.04.005 BindingDB Entry DOI: 10.7270/Q2QZ28RQ
COMSATS Institute of Information Technology					More data for this Ligand-Target Pair
Urease subunit alpha (Bacillus pasteurii)	BDBM181107 (3-(3-Nitrobenzosulfonyl)-(4-hydroxycoumarin) (14)) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.62E+4	n/a	n/a	n/a	n/a	n/a	30
COMSATS Institute of Information Technology					Assay Description Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 �L of buffers containing 100 mMol urea were incubated with 5 �L...				Bioorg Chem 66: 111-6 (2016) Article DOI: 10.1016/j.bioorg.2016.04.005 BindingDB Entry DOI: 10.7270/Q2QZ28RQ
COMSATS Institute of Information Technology					More data for this Ligand-Target Pair
Urease subunit alpha (Bacillus pasteurii)	BDBM181108 (3-(1-Naphthosulfonyl)-(4-hydroxycoumarin) (16)) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.95E+4	n/a	n/a	n/a	n/a	n/a	30
COMSATS Institute of Information Technology					Assay Description Reaction mixtures comprising one unit of urease enzyme (B. pasteurii) solution and 55 �L of buffers containing 100 mMol urea were incubated with 5 �L...				Bioorg Chem 66: 111-6 (2016) Article DOI: 10.1016/j.bioorg.2016.04.005 BindingDB Entry DOI: 10.7270/Q2QZ28RQ
COMSATS Institute of Information Technology					More data for this Ligand-Target Pair

* indicates data uncertainty>20%