Affinity Data by PubMed id=27167503

PubMed code 27167503

Found 17 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peregrin (Homo sapiens (Human))	BDBM50182416 (CHEMBL3818270) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by biotinylated peptide a...				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50182416 (CHEMBL3818270) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50121955 (4-Phenyl-pyridine \| CHEMBL109074 \| US11634391, Com...) Show SMILES c1ccc(cc1)-c1ccncc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182418 (CHEBI:81783 \| TRICYCLAZOLE) Show SMILES Cc1cccc2sc3nncn3c12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50068775 (2H-Isoquinolin-1-one \| CHEMBL339695 \| isoquinolin-...) Show SMILES O=c1[nH]ccc2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182407 (5-Hydroxyquinoline \| CHEBI:48993 \| CHEMBL589127) Show SMILES Oc1cccc2ncccc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182411 (CHEMBL3819561) Show SMILES CN1C(=O)CNc2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182414 (CHEMBL3817859) Show SMILES CC(=O)c1c[nH]c2c(C)cccc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182408 (CHEMBL3818063) Show SMILES Brc1ccc2NC(=O)CNc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182406 (CHEMBL1416049) Show SMILES Oc1[nH]c(S)nc2nc(S)nc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50182410 (CHEMBL3818199) Show SMILES FC(F)(F)c1ccc2NCC(=O)Nc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182412 (CHEMBL3818285) Show SMILES C[C@@H]1Nc2ccccc2NC1=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182413 (CHEMBL3819225) Show SMILES CC[C@H]1Nc2ccc(cc2NC1=O)C(O)=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182417 (CHEMBL3818787) Show SMILES O=c1[nH]c2[nH]c(=S)[nH]c(=O)c2[nH]1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50182415 (CHEMBL3818519) Show SMILES Cn1nccc1C(=O)Nc1ccc(F)cc1F Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50240538 (CHEMBL57481 \| Isoquinolin-5-ol) Show SMILES Oc1cccc2cnccc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50172107 (CHEMBL3810303) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%