Affinity Data by PubMed id=2724299

PubMed code 2724299

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018179 (2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...) Show SMILES OC(=O)C1=Cc2sc(Cn3ccnc3)cc2CC1 \|t:3\| Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A synthetase in rabbits				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50018179 (2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...) Show SMILES OC(=O)C1=Cc2sc(Cn3ccnc3)cc2CC1 \|t:3\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A2 synthetase in rabbits				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018179 (2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...) Show SMILES OC(=O)C1=Cc2sc(Cn3ccnc3)cc2CC1 \|t:3\| Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018181 (2-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)C1CCc2cc(Cn3ccnc3)sc2C1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A synthetase in humans				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018181 (2-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)C1CCc2cc(Cn3ccnc3)sc2C1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A synthetase in humans				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50018181 (2-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)C1CCc2cc(Cn3ccnc3)sc2C1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018183 (2-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)C1CCc2sc(Cn3ccnc3)cc2C1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018186 (2-Imidazol-1-ylmethyl-6,7-dihydro-benzo[b]thiophen...) Show SMILES OC(=O)C1=Cc2cc(Cn3ccnc3)sc2CC1 \|t:3\| Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018178 (2-(2-Imidazol-1-yl-ethyl)-6,7-dihydro-benzo[b]thio...) Show SMILES OC(=O)C1=Cc2cc(CCn3ccnc3)sc2CC1 \|t:3\| Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM7962 (4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...) Show SMILES OC(=O)c1ccc(OCCn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A2 synthetase in rabbits				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM7962 (4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...) Show SMILES OC(=O)c1ccc(OCCn2ccnc2)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018176 (2-(Imidazol-1-yl-phenyl-methyl)-6,7-dihydro-benzo[...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018184 (5-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)c1cc2CC(Cn3ccnc3)CCc2s1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM7962 (4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...) Show SMILES OC(=O)c1ccc(OCCn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A synthetase in humans				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018180 (2-(2-Imidazol-1-yl-ethyl)-4,5,6,7-tetrahydro-benzo...) Show SMILES OC(=O)C1CCc2sc(CCn3ccnc3)cc2C1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018177 (2-(2-Imidazol-1-yl-ethyl)-4,5,6,7-tetrahydro-benzo...) Show SMILES OC(=O)C1CCc2cc(CCn3ccnc3)sc2C1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018185 (6-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)c1cc2CCC(Cn3ccnc3)Cc2s1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018188 (2-(Cyclohexyl-imidazol-1-yl-methyl)-6,7-dihydro-be...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018182 (2-(2-Imidazol-1-yl-ethyl)-4,5-dihydro-benzo[b]thio...) Show SMILES OC(=O)C1=Cc2sc(CCn3ccnc3)cc2CC1 \|t:3\| Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018187 (2-(1-Imidazol-1-yl-2,2-dimethyl-propyl)-6,7-dihydr...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%