Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201785 (CHEMBL3939072) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201770 (CHEMBL3966682) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201813 (CHEMBL584338) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201797 (CHEMBL516585) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201786 (CHEMBL1098543) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201799 (CHEMBL238792) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201770 (CHEMBL3966682) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201813 (CHEMBL584338) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201786 (CHEMBL1098543) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201799 (CHEMBL238792) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201785 (CHEMBL3939072) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50201797 (CHEMBL516585) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM81348 (β-Lapachone (A3) | Beta lapachone | R115 (Rea...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM81348 (β-Lapachone (A3) | Beta lapachone | R115 (Rea...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Federal University of Minas Gerais Curated by ChEMBL | Assay Description Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ... | Eur J Med Chem 122: 1-16 (2016) Article DOI: 10.1016/j.ejmech.2016.06.019 BindingDB Entry DOI: 10.7270/Q2NV9M74 | |||||||||||
More data for this Ligand-Target Pair |