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PubMed code 27388635

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM16673
PNG
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
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Similars

DrugBank
PDB
Article
PubMed
n/an/a 100n/an/an/an/a7.4n/a



Bharati Vidyapeeth's College of Pharmacy



Assay Description
The inhibition was carried out in 96-well polystyrene round bottomed plates. These plates were precoated with 100 ul per well of 50 ug per ml poly(...


Bioorg Chem 67: 139-47 (2016)


Article DOI: 10.1016/j.bioorg.2016.06.006
BindingDB Entry DOI: 10.7270/Q2GH9GR6
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM192706
PNG
(2-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)phenoxy...)
Show SMILES O=C(COc1ccc(\C=C2/SC(=O)NC2=O)cc1)Nc1nc2ccccc2s1
Show InChI InChI=1S/C19H13N3O4S2/c23-16(21-18-20-13-3-1-2-4-14(13)27-18)10-26-12-7-5-11(6-8-12)9-15-17(24)22-19(25)28-15/h1-9H,10H2,(H,20,21,23)(H,22,24,25)/b15-9-
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KEGG

UniProtKB/SwissProt

B.MOAD
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antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 500n/an/an/an/a7.4n/a



Bharati Vidyapeeth's College of Pharmacy



Assay Description
The inhibition was carried out in 96-well polystyrene round bottomed plates. These plates were precoated with 100 ul per well of 50 ug per ml poly(...


Bioorg Chem 67: 139-47 (2016)


Article DOI: 10.1016/j.bioorg.2016.06.006
BindingDB Entry DOI: 10.7270/Q2GH9GR6
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%