Affinity Data by PubMed id=27567368

PubMed code 27567368

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50194198 (CHEMBL3890511) Show SMILES Oc1ccc(CCN(CCc2ccccc2)CC2CCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50194197 (CHEMBL3923010) Show SMILES Oc1cccc(CCN(CCc2ccccc2)CCc2ccccc2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	211	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50194236 (CHEMBL3950863) Show SMILES Oc1ccc(CCN(CCc2ccccc2)CC2CC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	218	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50194198 (CHEMBL3890511) Show SMILES Oc1ccc(CCN(CCc2ccccc2)CC2CCC2)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	731	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50194236 (CHEMBL3950863) Show SMILES Oc1ccc(CCN(CCc2ccccc2)CC2CC2)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50194198 (CHEMBL3890511) Show SMILES Oc1ccc(CCN(CCc2ccccc2)CC2CCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]pCl-DPDPE from human delta opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50194236 (CHEMBL3950863) Show SMILES Oc1ccc(CCN(CCc2ccccc2)CC2CC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]pCl-DPDPE from human delta opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50194197 (CHEMBL3923010) Show SMILES Oc1cccc(CCN(CCc2ccccc2)CCc2ccccc2)c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50194197 (CHEMBL3923010) Show SMILES Oc1cccc(CCN(CCc2ccccc2)CCc2ccccc2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]pCl-DPDPE from human delta opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50194198 (CHEMBL3890511) Show SMILES Oc1ccc(CCN(CCc2ccccc2)CC2CCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	109	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Agonist activity at human kappa opioid receptor expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS assay				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50194197 (CHEMBL3923010) Show SMILES Oc1cccc(CCN(CCc2ccccc2)CCc2ccccc2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Agonist activity at human kappa opioid receptor expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS assay				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50194236 (CHEMBL3950863) Show SMILES Oc1ccc(CCN(CCc2ccccc2)CC2CC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Agonist activity at human kappa opioid receptor expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS assay				Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%