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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human)) | BDBM50210628 (CHEMBL3946861) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Hamdard University Curated by ChEMBL | Assay Description Inhibition of human PDE3A using fluorescein-labelled cAMP as substrate measured after 60 mins by IMAP TR-FRET assay | Eur J Med Chem 125: 143-189 (2017) Article DOI: 10.1016/j.ejmech.2016.09.023 BindingDB Entry DOI: 10.7270/Q23T9K6Z | |||||||||||
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