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PubMed code 27746002

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50200502
PNG
(CHEMBL3976283)
Show SMILES Fc1ccc(cc1)C1=C(c2ccccc2C1=O)c1ccncc1 |t:8|
Show InChI InChI=1S/C20H12FNO/c21-15-7-5-13(6-8-15)19-18(14-9-11-22-12-10-14)16-3-1-2-4-17(16)20(19)23/h1-12H
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 899n/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length GST-tagged MAPK14 phosphorylation expressed in Escherichia coli in presence of 100 uM of ATP by direct Z-...


Bioorg Med Chem Lett 26: 5160-5163 (2016)


Article DOI: 10.1016/j.bmcl.2016.10.001
BindingDB Entry DOI: 10.7270/Q2PZ5BST
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50200502
PNG
(CHEMBL3976283)
Show SMILES Fc1ccc(cc1)C1=C(c2ccccc2C1=O)c1ccncc1 |t:8|
Show InChI InChI=1S/C20H12FNO/c21-15-7-5-13(6-8-15)19-18(14-9-11-22-12-10-14)16-3-1-2-4-17(16)20(19)23/h1-12H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.35E+3n/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length GST-tagged MAPK14 phosphorylation expressed in Escherichia coli in presence of 500 uM of ATP by direct Z-...


Bioorg Med Chem Lett 26: 5160-5163 (2016)


Article DOI: 10.1016/j.bmcl.2016.10.001
BindingDB Entry DOI: 10.7270/Q2PZ5BST
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%