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PubMed code 27899265

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNMT3A2/3L complex


(Homo sapiens (Human))
BDBM50206867
PNG
(CHEMBL3971712)
Show SMILES OC(=O)c1ccc(Cl)cc1N1C(=O)c2ccc(cc2C1=O)C(=O)Nc1ccc(Br)cc1C(O)=O
PDB
MMDB

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B.MOAD
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.10E+4n/an/an/an/an/an/a



University of Science and Technology of China

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged DNMT3A (623 to 908 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) coexpressing DNMT3L (160 ...


Bioorg Med Chem Lett 27: 342-346 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.023
BindingDB Entry DOI: 10.7270/Q2N87CSS
More data for this
Ligand-Target Pair
DNMT3A2/3L complex


(Homo sapiens (Human))
BDBM50206868
PNG
(CHEMBL1424505)
Show SMILES CC(N1C(=O)c2ccc(cc2C1=O)C(=O)Nc1ccc(Br)cc1C(O)=O)c1ccccc1
PDB
MMDB

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UniProtKB/SwissProt

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.65E+4n/an/an/an/an/an/a



University of Science and Technology of China

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged DNMT3A (623 to 908 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) coexpressing DNMT3L (160 ...


Bioorg Med Chem Lett 27: 342-346 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.023
BindingDB Entry DOI: 10.7270/Q2N87CSS
More data for this
Ligand-Target Pair
DNMT3A2/3L complex


(Homo sapiens (Human))
BDBM50206866
PNG
(CHEMBL3922548)
Show SMILES OC(=O)c1ccc(NC(=O)c2ccc3C(=O)N(Cc4ccco4)C(=O)c3c2)cc1
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.40E+4n/an/an/an/an/an/a



University of Science and Technology of China

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged DNMT3A (623 to 908 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) coexpressing DNMT3L (160 ...


Bioorg Med Chem Lett 27: 342-346 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.023
BindingDB Entry DOI: 10.7270/Q2N87CSS
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%