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PubMed code 27914800

Compile data set for download or QSAR
Found 11 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein 1


(Homo sapiens (Human))
BDBM50205620
PNG
(CHEMBL3943212)
Show SMILES [H][C@]12OC[C@H](N(C(=O)Cc3ccc(O)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r|
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PC cid
PC sid
UniChem
Article
PubMed
3.10E+3n/an/an/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Competitive inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate ...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205620
PNG
(CHEMBL3943212)
Show SMILES [H][C@]12OC[C@H](N(C(=O)Cc3ccc(O)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r|
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205625
PNG
(CHEMBL3901491)
Show SMILES [H][C@]12OC[C@H](N(C(=O)Cc3ccc(O)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@@H]2N(C(=O)Cc1ccc(O)cc1)C(C)(C)C(=O)NC1CCCCC1 |r|
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PC sid
UniChem
Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205624
PNG
(CHEMBL3963267)
Show SMILES [H][C@]12OC[C@H](N(C(=O)Cc3ccc(OC)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r|
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UniChem
Article
PubMed
n/an/a 1.25E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM50205625
PNG
(CHEMBL3901491)
Show SMILES [H][C@]12OC[C@H](N(C(=O)Cc3ccc(O)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@@H]2N(C(=O)Cc1ccc(O)cc1)C(C)(C)C(=O)NC1CCCCC1 |r|
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n/an/a 1.33E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM50205623
PNG
(CHEMBL3951954)
Show SMILES [H][C@]12OC[C@H](N(C(=O)Cc3ccc(F)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r|
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UniChem
Article
PubMed
n/an/a 1.85E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205623
PNG
(CHEMBL3951954)
Show SMILES [H][C@]12OC[C@H](N(C(=O)Cc3ccc(F)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r|
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UniChem
Article
PubMed
n/an/a 2.21E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM50205620
PNG
(CHEMBL3943212)
Show SMILES [H][C@]12OC[C@H](N(C(=O)Cc3ccc(O)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r|
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UniChem
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n/an/a 2.49E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM50205624
PNG
(CHEMBL3963267)
Show SMILES [H][C@]12OC[C@H](N(C(=O)Cc3ccc(OC)cc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r|
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UniChem
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n/an/a 2.72E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205621
PNG
(CHEMBL3891631)
Show SMILES [H][C@]12OC[C@H](N(C(=O)c3ccccc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r|
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antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.00E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens (Human))
BDBM50205621
PNG
(CHEMBL3891631)
Show SMILES [H][C@]12OC[C@H](N(C(=O)c3ccccc3)C(C)(C)C(=O)NC3CCCCC3)[C@@]1([H])OC[C@H]2OCc1ccccc1 |r|
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.72E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%