Affinity Data by PubMed id=28062195

PubMed code 28062195

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50209837 (CHEMBL3885083) Show SMILES CCCCCCCCCCCCCCCNC(=O)c1ccccc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ Vita-Salute San Raffaele Curated by ChEMBL					Assay Description Inhibition of recombinant human NAAA using PAMCA as substrate preincubated for 30 mins followed by substrate addition measured every 3 mins for 2.5 h...				Bioorg Med Chem 25: 1242-1249 (2017) Article DOI: 10.1016/j.bmc.2016.12.042 BindingDB Entry DOI: 10.7270/Q29K4D7W
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50209840 (CHEMBL3885119) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ Vita-Salute San Raffaele Curated by ChEMBL					Assay Description Inhibition of recombinant human NAAA using PAMCA as substrate preincubated for 30 mins followed by substrate addition measured every 3 mins for 2.5 h...				Bioorg Med Chem 25: 1242-1249 (2017) Article DOI: 10.1016/j.bmc.2016.12.042 BindingDB Entry DOI: 10.7270/Q29K4D7W
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50171286 (3-Hydroxy-N-pentadecyl-propionamide \| CHEMBL423904...) Show SMILES CCCCCCCCCCCCCCCNC(=O)CCO Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ Vita-Salute San Raffaele Curated by ChEMBL					Assay Description Inhibition of recombinant human NAAA using PAMCA as substrate preincubated for 30 mins followed by substrate addition measured every 3 mins for 2.5 h...				Bioorg Med Chem 25: 1242-1249 (2017) Article DOI: 10.1016/j.bmc.2016.12.042 BindingDB Entry DOI: 10.7270/Q29K4D7W
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50209836 (CHEMBL3885323) Show SMILES CCCCCCCCCCCCCCCNC(=O)c1cc(O)ccc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ Vita-Salute San Raffaele Curated by ChEMBL					Assay Description Inhibition of recombinant human NAAA using PAMCA as substrate preincubated for 30 mins followed by substrate addition measured every 3 mins for 2.5 h...				Bioorg Med Chem 25: 1242-1249 (2017) Article DOI: 10.1016/j.bmc.2016.12.042 BindingDB Entry DOI: 10.7270/Q29K4D7W
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50309176 (CHEMBL190429 \| N-Pentadecyl-benzamide \| N-pentadec...) Show SMILES CCCCCCCCCCCCCCCNC(=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ Vita-Salute San Raffaele Curated by ChEMBL					Assay Description Inhibition of recombinant human NAAA using PAMCA as substrate preincubated for 30 mins followed by substrate addition measured every 3 mins for 2.5 h...				Bioorg Med Chem 25: 1242-1249 (2017) Article DOI: 10.1016/j.bmc.2016.12.042 BindingDB Entry DOI: 10.7270/Q29K4D7W
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50209839 (CHEMBL3883768) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ Vita-Salute San Raffaele Curated by ChEMBL					Assay Description Inhibition of recombinant human NAAA using PAMCA as substrate preincubated for 30 mins followed by substrate addition measured every 3 mins for 2.5 h...				Bioorg Med Chem 25: 1242-1249 (2017) Article DOI: 10.1016/j.bmc.2016.12.042 BindingDB Entry DOI: 10.7270/Q29K4D7W
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50209838 (CHEMBL3884680) Show SMILES CCCCCCCCCCCCCCCNC(=O)c1ccncc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ Vita-Salute San Raffaele Curated by ChEMBL					Assay Description Inhibition of recombinant human NAAA using PAMCA as substrate preincubated for 30 mins followed by substrate addition measured every 3 mins for 2.5 h...				Bioorg Med Chem 25: 1242-1249 (2017) Article DOI: 10.1016/j.bmc.2016.12.042 BindingDB Entry DOI: 10.7270/Q29K4D7W
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50209841 (CHEMBL3884760) Show SMILES CCCCCCCCCCCCCCCNC(=O)c1ccc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ Vita-Salute San Raffaele Curated by ChEMBL					Assay Description Inhibition of recombinant human NAAA using PAMCA as substrate preincubated for 30 mins followed by substrate addition measured every 3 mins for 2.5 h...				Bioorg Med Chem 25: 1242-1249 (2017) Article DOI: 10.1016/j.bmc.2016.12.042 BindingDB Entry DOI: 10.7270/Q29K4D7W
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%