Affinity Data by PubMed id=28481502

PubMed code 28481502

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase [1-303] (Schistosoma mansoni)	BDBM65496 (SmNACE inhibitor, 2) Show SMILES Cc1occc1C(=O)N\N=C\c1cc(Cl)ccc1O Show InChI	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	7.4	37
CAMB UMR 7199 CNRS-Universite de Strasbourg					Assay Description SmNACE activity and inhibition were measured with a sensitive, continuous, fluorometric assay platform that used 1,N6-ethenonicotinamide adenine dinu...				ACS Chem Biol 12: 1787-1795 (2017) Article DOI: 10.1021/acschembio.7b00186 BindingDB Entry DOI: 10.7270/Q2JM27SR
CAMB UMR 7199 CNRS-Universite de Strasbourg					More data for this Ligand-Target Pair
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (Schistosoma mansoni)	BDBM65496 (SmNACE inhibitor, 2) Show SMILES Cc1occc1C(=O)N\N=C\c1cc(Cl)ccc1O Show InChI	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	7.4	37
CAMB UMR 7199 CNRS-Universite de Strasbourg					Assay Description SmNACE activity and inhibition were measured with a sensitive, continuous, fluorometric assay platform that used 1,N6-ethenonicotinamide adenine dinu...				ACS Chem Biol 12: 1787-1795 (2017) Article DOI: 10.1021/acschembio.7b00186 BindingDB Entry DOI: 10.7270/Q2JM27SR
CAMB UMR 7199 CNRS-Universite de Strasbourg					More data for this Ligand-Target Pair
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase [1-303] (Schistosoma mansoni)	BDBM65499 (Zn(II) complex of 2) Show SMILES CC1OCCC1C1NN2Cc3cc(C)ccc3O[Zn+]2O1 Show InChI	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	7.4	37
CAMB UMR 7199 CNRS-Universite de Strasbourg					Assay Description SmNACE activity and inhibition were measured with a sensitive, continuous, fluorometric assay platform that used 1,N6-ethenonicotinamide adenine dinu...				ACS Chem Biol 12: 1787-1795 (2017) Article DOI: 10.1021/acschembio.7b00186 BindingDB Entry DOI: 10.7270/Q2JM27SR
CAMB UMR 7199 CNRS-Universite de Strasbourg					More data for this Ligand-Target Pair
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase [1-303] (Schistosoma mansoni)	BDBM65500 (SmNACE inhibitor, 3) Show SMILES O=C(Nc1nc(=O)c2ccccc2s1)c1ccco1 Show InChI	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.4	37
CAMB UMR 7199 CNRS-Universite de Strasbourg					Assay Description SmNACE activity and inhibition were measured with a sensitive, continuous, fluorometric assay platform that used 1,N6-ethenonicotinamide adenine dinu...				ACS Chem Biol 12: 1787-1795 (2017) Article DOI: 10.1021/acschembio.7b00186 BindingDB Entry DOI: 10.7270/Q2JM27SR
CAMB UMR 7199 CNRS-Universite de Strasbourg					More data for this Ligand-Target Pair
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (Schistosoma mansoni)	BDBM65500 (SmNACE inhibitor, 3) Show SMILES O=C(Nc1nc(=O)c2ccccc2s1)c1ccco1 Show InChI	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.4	37
CAMB UMR 7199 CNRS-Universite de Strasbourg					Assay Description SmNACE activity and inhibition were measured with a sensitive, continuous, fluorometric assay platform that used 1,N6-ethenonicotinamide adenine dinu...				ACS Chem Biol 12: 1787-1795 (2017) Article DOI: 10.1021/acschembio.7b00186 BindingDB Entry DOI: 10.7270/Q2JM27SR
CAMB UMR 7199 CNRS-Universite de Strasbourg					More data for this Ligand-Target Pair
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (Schistosoma mansoni)	BDBM65495 (SmNACE inhibitor, 1) Show SMILES Cc1occc1C(=O)N\N=C\c1ccc(O)c(O)c1 Show InChI	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	7.4	37
CAMB UMR 7199 CNRS-Universite de Strasbourg					Assay Description SmNACE activity and inhibition were measured with a sensitive, continuous, fluorometric assay platform that used 1,N6-ethenonicotinamide adenine dinu...				ACS Chem Biol 12: 1787-1795 (2017) Article DOI: 10.1021/acschembio.7b00186 BindingDB Entry DOI: 10.7270/Q2JM27SR
CAMB UMR 7199 CNRS-Universite de Strasbourg					More data for this Ligand-Target Pair
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase [1-303] (Schistosoma mansoni)	BDBM65495 (SmNACE inhibitor, 1) Show SMILES Cc1occc1C(=O)N\N=C\c1ccc(O)c(O)c1 Show InChI	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	7.4	37
CAMB UMR 7199 CNRS-Universite de Strasbourg					Assay Description SmNACE activity and inhibition were measured with a sensitive, continuous, fluorometric assay platform that used 1,N6-ethenonicotinamide adenine dinu...				ACS Chem Biol 12: 1787-1795 (2017) Article DOI: 10.1021/acschembio.7b00186 BindingDB Entry DOI: 10.7270/Q2JM27SR
CAMB UMR 7199 CNRS-Universite de Strasbourg					More data for this Ligand-Target Pair
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (Schistosoma mansoni)	BDBM65499 (Zn(II) complex of 2) Show SMILES CC1OCCC1C1NN2Cc3cc(C)ccc3O[Zn+]2O1 Show InChI	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	7.4	37
CAMB UMR 7199 CNRS-Universite de Strasbourg					Assay Description SmNACE activity and inhibition were measured with a sensitive, continuous, fluorometric assay platform that used 1,N6-ethenonicotinamide adenine dinu...				ACS Chem Biol 12: 1787-1795 (2017) Article DOI: 10.1021/acschembio.7b00186 BindingDB Entry DOI: 10.7270/Q2JM27SR
CAMB UMR 7199 CNRS-Universite de Strasbourg					More data for this Ligand-Target Pair

* indicates data uncertainty>20%