Affinity Data by PubMed id=2967376

PubMed code 2967376

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011247 (7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...) Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	774	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	774	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%