Affinity Data by PubMed id=2999400

PubMed code 2999400

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-2A adrenergic receptor (BOVINE)	BDBM50021195 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortex				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50021195 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of human plasma renin				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (BOVINE)	BDBM50021196 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortex				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50021196 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of hog kidney renin				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of hog kidney renin				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (BOVINE)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortex				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (BOVINE)	BDBM50021197 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortex				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM50021195 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for its ability to displace [3H]-prazosin from alpha1-Adrenoreceptor of calf cerebral cortex				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50021197 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of human plasma renin				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM50021196 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for its ability to displace [3H]-prazosin from alpha1-Adrenoreceptor of calf cerebral cortex				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for its ability to displace [3H]-prazosin from alpha1-Adrenoreceptor of calf cerebral cortex				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM50021197 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Evaluated for its ability to displace [3H]-prazosin from alpha1-Adrenoreceptor of calf cerebral cortex				J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%