Affinity Data by PubMed id=3346870

PubMed code 3346870

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023331 ((+)-pyrido[3,4-b]homotropane \| (+/-)-pyrido[3,4-b]...) Show SMILES C1CC2NC1CCc1ccncc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023330 (1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone \| 1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023330 (1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone \| 1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023331 ((+)-pyrido[3,4-b]homotropane \| (+/-)-pyrido[3,4-b]...) Show SMILES C1CC2NC1CCc1ccncc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023328 (3-Pyrrolidin-2-yl-pyridine \| CHEMBL1132 \| Nornicot...) Show SMILES C1CNC(C1)c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023327 (3-Methyl-4,13-diaza-tricyclo[8.2.1.02,7]trideca-...) Show SMILES Cc1nccc2CCC3CCC(N3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023328 (3-Pyrrolidin-2-yl-pyridine \| CHEMBL1132 \| Nornicot...) Show SMILES C1CNC(C1)c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023327 (3-Methyl-4,13-diaza-tricyclo[8.2.1.02,7]trideca-...) Show SMILES Cc1nccc2CCC3CCC(N3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023329 (13-Methyl-4,13-diaza-tricyclo[8.2.1.02,7]trideca...) Show SMILES CN1C2CCC1c1cnccc1CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023329 (13-Methyl-4,13-diaza-tricyclo[8.2.1.02,7]trideca...) Show SMILES CN1C2CCC1c1cnccc1CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%