Affinity Data by PubMed id=3701793

PubMed code 3701793

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50024974 (4-Hydroxy-6-[2-(3,5,3'',5''-tetramethyl-biphenyl-2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductase				J Med Chem 29: 852-5 (1986) BindingDB Entry DOI: 10.7270/Q22F7MFN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50024972 ((+) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-v...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductase				J Med Chem 29: 852-5 (1986) BindingDB Entry DOI: 10.7270/Q22F7MFN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50024973 (6-[2-(3,5-Dichloro-biphenyl-2-yl)-vinyl]-4-hydroxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductase				J Med Chem 29: 852-5 (1986) BindingDB Entry DOI: 10.7270/Q22F7MFN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50024977 (6-(1,3-Dichloro-6-fluoro-9H-fluoren-9-ylmethyl)-4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductase				J Med Chem 29: 852-5 (1986) BindingDB Entry DOI: 10.7270/Q22F7MFN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50024975 (6-(1,3-Dimethyl-fluoren-9-ylidenemethyl)-4-hydroxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductase				J Med Chem 29: 852-5 (1986) BindingDB Entry DOI: 10.7270/Q22F7MFN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50024978 (4-Hydroxy-6-(1,3,5,7-tetramethyl-fluoren-9-ylidene...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductase				J Med Chem 29: 852-5 (1986) BindingDB Entry DOI: 10.7270/Q22F7MFN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50024971 (6-Fluoren-9-ylidenemethyl-4-hydroxy-tetrahydro-pyr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductase				J Med Chem 29: 852-5 (1986) BindingDB Entry DOI: 10.7270/Q22F7MFN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50024976 (6-(2-Biphenyl-2-yl-vinyl)-4-hydroxy-tetrahydro-pyr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductase				J Med Chem 29: 852-5 (1986) BindingDB Entry DOI: 10.7270/Q22F7MFN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%