Affinity Data by PubMed id=3783602

PubMed code 3783602

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226058 (CHEMBL298503) Show SMILES CCc1c(C)n(CC)c2ccc(cc12)N(C)C Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226059 (CHEMBL52909) Show SMILES CCc1c(C)[nH]c2ccc(cc12)N(C)C Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226057 (CHEMBL298780) Show SMILES CCc1c(C)n(C)c2ccc(cc12)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226056 (CHEMBL81841) Show SMILES CCc1c(C)c2cc(ccc2n1C)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226060 (CHEMBL82478) Show SMILES CN(C)c1ccc2n(C)c(C)c(C)c2c1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226054 (CHEMBL81220) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226060 (CHEMBL82478) Show SMILES CN(C)c1ccc2n(C)c(C)c(C)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226061 (CHEMBL312405) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its binding affinity towards 5-hydroxytryptamine 1 receptor in rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226125 (CHEMBL52816) Show SMILES CCc1c(C)n(C(C)C)c2ccc(cc12)N(C)C Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226055 (CHEMBL78430) Show SMILES CCc1c(C)n(C)c2c(cccc12)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226055 (CHEMBL78430) Show SMILES CCc1c(C)n(C)c2c(cccc12)N(C)C Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226058 (CHEMBL298503) Show SMILES CCc1c(C)n(CC)c2ccc(cc12)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226105 (CHEMBL81187) Show SMILES CCCn1c(C)c(CC)c2cc(ccc12)N(C)C Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226062 (CHEMBL78593) Show SMILES CCc1c(C)[nH]c2ccc(N(C)C)c(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226056 (CHEMBL81841) Show SMILES CCc1c(C)c2cc(ccc2n1C)N(C)C Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226059 (CHEMBL52909) Show SMILES CCc1c(C)[nH]c2ccc(cc12)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226057 (CHEMBL298780) Show SMILES CCc1c(C)n(C)c2ccc(cc12)N(C)C Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226054 (CHEMBL81220) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50226062 (CHEMBL78593) Show SMILES CCc1c(C)[nH]c2ccc(N(C)C)c(Cl)c12 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1 receptor in brain cortical membranes of rat				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226105 (CHEMBL81187) Show SMILES CCCn1c(C)c(CC)c2cc(ccc12)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226061 (CHEMBL312405) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50226125 (CHEMBL52816) Show SMILES CCc1c(C)n(C(C)C)c2ccc(cc12)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain cortical membranes				J Med Chem 29: 2415-8 (1986) BindingDB Entry DOI: 10.7270/Q2V69MT2
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%