Affinity Data by BDB articleid=3897

Articleid 3897

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-1 adrenergic receptor (Rattus norvegicus (Rat))	BDBM25761 (Anapriline \| Avlocardyl \| CHEMBL27 \| PROPANOLOL(-)...) Show SMILES CC(C)NCC(O)COc1cccc2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Warsaw					Assay Description Radioligand receptor binding studies were conducted in the rat brain.				Medicinal Chemistry Research 17: 507-514 (2008) BindingDB Entry DOI: 10.7270/Q2Z036S7
The Medical University of Warsaw					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50222218 (CHEBI:51137 \| Mianserin) Show SMILES CN1CCN2C(C1)c1ccccc1Cc1ccccc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Warsaw					Assay Description Radioligand receptor binding studies were conducted in the rat brain.				Medicinal Chemistry Research 17: 507-514 (2008) BindingDB Entry DOI: 10.7270/Q2Z036S7
The Medical University of Warsaw					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM31005 (2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...) Show SMILES Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Warsaw					Assay Description Radioligand receptor binding studies were conducted in the rat brain.				Medicinal Chemistry Research 17: 507-514 (2008) BindingDB Entry DOI: 10.7270/Q2Z036S7
The Medical University of Warsaw					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Warsaw					Assay Description Radioligand receptor binding studies were conducted in the rat brain.				Medicinal Chemistry Research 17: 507-514 (2008) BindingDB Entry DOI: 10.7270/Q2Z036S7
The Medical University of Warsaw					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM93102 (4-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propoxy]-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars		336	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Warsaw					Assay Description Radioligand receptor binding studies were conducted in the rat brain.				Medicinal Chemistry Research 17: 507-514 (2008) BindingDB Entry DOI: 10.7270/Q2Z036S7
The Medical University of Warsaw					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM93102 (4-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propoxy]-4-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars		370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Warsaw					Assay Description Radioligand receptor binding studies were conducted in the rat brain.				Medicinal Chemistry Research 17: 507-514 (2008) BindingDB Entry DOI: 10.7270/Q2Z036S7
The Medical University of Warsaw					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Rattus norvegicus (Rat))	BDBM93102 (4-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propoxy]-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars		3.85E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Warsaw					Assay Description Radioligand receptor binding studies were conducted in the rat brain.				Medicinal Chemistry Research 17: 507-514 (2008) BindingDB Entry DOI: 10.7270/Q2Z036S7
The Medical University of Warsaw					More data for this Ligand-Target Pair

* indicates data uncertainty>20%