Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM93103 (COX inhibitor, 5a) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a | |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM93105 (COX inhibitor, 8) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a | |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM93104 (COX inhibitor, 5b) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a | |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM93106 (COX inhibitor, 9) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a | |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 [582-599] (Homo sapiens (Human)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | n/a | n/a | 2.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 [582-599] (Homo sapiens (Human)) | BDBM93106 (COX inhibitor, 9) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 7.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 [582-599] (Homo sapiens (Human)) | BDBM93105 (COX inhibitor, 8) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | 8.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 [582-599] (Homo sapiens (Human)) | BDBM93103 (COX inhibitor, 5a) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 [582-599] (Homo sapiens (Human)) | BDBM93104 (COX inhibitor, 5b) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
Shahid Beheshti University | Assay Description The ability of the test compounds to inhibit ovine COX-1 and COX-2 was determined using chemiluminescent enzyme assays kit according to our previousl... | Med Chem Res 19: 782-793 (2009) BindingDB Entry DOI: 10.7270/Q2T72G2X | |||||||||||
More data for this Ligand-Target Pair |