Affinity Data by PubMed id=3941405

PubMed code 3941405

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Papain (Carica papaya)	BDBM50026029 (2-Acetylamino-N-cyanomethyl-3-phenyl-propionamide ...) Show SMILES CC(=O)NC(Cc1ccccc1)C(=O)NCC#N Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Papain				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50026017 (2-Amino-N-(benzyl-cyano-methyl)-acetamide \| CHEMBL...) Show SMILES NCC(=O)NC(Cc1ccccc1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50026019 (4-(2-Acetylamino-3-phenyl-propionylamino)-but-2-en...) Show SMILES COC(=O)\C=C\CNC(=O)C(Cc1ccccc1)NC(C)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Papain				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50026012 (2-Acetylamino-3-phenyl-N-thiocarbamoylmethyl-propi...) Show SMILES CC(=O)NC(Cc1ccccc1)C(=O)NCC(N)=S Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Papain				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50026018 (2-Amino-N-(1-benzyl-3-methanesulfonyl-allyl)-aceta...) Show SMILES CS(=O)(=O)\C=C\C(Cc1ccccc1)NC(=O)CN Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50026015 (4-(2-Amino-acetylamino)-5-phenyl-pent-2-enoic acid...) Show SMILES COC(=O)\C=C\C(Cc1ccccc1)NC(=O)CN Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50452186 (CHEMBL2369764) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.70E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Papain				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50026026 (CHEMBL13246 \| N-(Benzyl-cyano-methyl)-acetamide) Show SMILES CC(=O)NC(Cc1ccccc1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.30E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Chymotrypsinogen				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50026027 (2-(2-Amino-acetylamino)-3-phenyl-propionamide \| CH...) Show SMILES NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	6.20E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of dipeptidyl Dipeptidyl aminopeptidase 1				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50026025 (2-Acetylamino-N-allyl-3-phenyl-propionamide \| CHEM...) Show SMILES CC(=O)NC(Cc1ccccc1)C(=O)NCC=C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.20E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Papain				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50026021 (2-Acetylamino-3-phenyl-propionamide \| CHEMBL274862) Show SMILES CC(=O)NC(Cc1ccccc1)C(N)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.39E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Chymotrypsinogen				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50026016 (4-(2-Acetylamino-3-phenyl-propionylamino)-butyric ...) Show SMILES COC(=O)CCCNC(=O)C(Cc1ccccc1)NC(C)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.95E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Papain				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50026024 (CHEMBL13056 \| N-(2-Phenyl-1-thiocarbamoyl-ethyl)-a...) Show SMILES CC(=O)NC(Cc1ccccc1)C(N)=S Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Chymotrypsinogen				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50026020 (CHEMBL13058 \| N-(1-Benzyl-3-methanesulfonyl-allyl)...) Show SMILES CC(=O)NC(Cc1ccccc1)\C=C\S(C)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.94E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Chymotrypsinogen				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50026011 ((E)-4-Acetylamino-5-phenyl-pent-2-enoic acid methy...) Show SMILES COC(=O)\C=C\C(Cc1ccccc1)NC(C)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.08E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Chymotrypsinogen				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%