Affinity Data by PubMed id=3989819

PubMed code 3989819

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50011036 ((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026334 (3-Hydroxy-3-pentadecyl-pentanedioic acid \| CHEMBL1...) Show SMILES CCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026339 (3-Hydroxy-3-tridecyl-pentanedioic acid \| CHEMBL155...) Show SMILES CCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026344 (3-Decyl-3-hydroxy-pentanedioic acid \| CHEMBL154728) Show SMILES CCCCCCCCCCC(O)(CC(O)=O)CC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026340 (3-Heptadecyl-3-hydroxy-pentanedioic acid \| CHEMBL1...) Show SMILES CCCCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026337 (3-Hexadecyl-3-hydroxy-pentanedioic acid \| CHEMBL15...) Show SMILES CCCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026343 (3-Hydroxy-3-tetradecyl-pentanedioic acid \| CHEMBL1...) Show SMILES CCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026342 (4-Hydroxy-4-pentadecyl-dihydro-pyran-2,6-dione \| C...) Show SMILES CCCCCCCCCCCCCCCC1(O)CC(=O)OC(=O)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026338 (3-Hydroxy-3-nonadecyl-pentanedioic acid \| CHEMBL15...) Show SMILES CCCCCCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026345 (4-Hydroxy-4-pentadecyl-tetrahydro-pyran-2-one \| CH...) Show SMILES CCCCCCCCCCCCCCCC1(O)CCOC(=O)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026341 (3-Hydroxy-3-pentadecyl-pentanedioic acid monoethyl...) Show SMILES CCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(=O)OCC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026335 (4-Pentadecyl-tetrahydro-pyran-2,4-diol \| CHEMBL154...) Show SMILES CCCCCCCCCCCCCCCC1(O)CCOC(O)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50026336 (3-Hydroxy-3-pentadecyl-pentanedioic acid diethyl e...) Show SMILES CCCCCCCCCCCCCCCC(O)(CC(=O)OCC)CC(=O)OCC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase from rat liver				J Med Chem 28: 597-601 (1985) BindingDB Entry DOI: 10.7270/Q2QV3KHN
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%