Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50011210 (CHEMBL342422 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against rat liver microsomal HMG-CoA reductase | Bioorg Med Chem Lett 2: 99-104 (1992) Article DOI: 10.1016/S0960-894X(00)80665-4 BindingDB Entry DOI: 10.7270/Q2X92B57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50280061 (CHEMBL8633 | Sodium; (E)-8-(3,6-difluoro-fluoren-9...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | >4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against rat liver microsomal HMG-CoA reductase | Bioorg Med Chem Lett 2: 99-104 (1992) Article DOI: 10.1016/S0960-894X(00)80665-4 BindingDB Entry DOI: 10.7270/Q2X92B57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50280060 (CHEMBL8746 | Sodium; (E)-7-[5-(4-fluoro-phenyl)-1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against rat liver microsomal HMG-CoA reductase | Bioorg Med Chem Lett 2: 99-104 (1992) Article DOI: 10.1016/S0960-894X(00)80665-4 BindingDB Entry DOI: 10.7270/Q2X92B57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50280059 (CHEMBL8800 | Sodium; (6E,8Z)-9-(4-fluoro-phenyl)-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against rat liver microsomal HMG-CoA reductase | Bioorg Med Chem Lett 2: 99-104 (1992) Article DOI: 10.1016/S0960-894X(00)80665-4 BindingDB Entry DOI: 10.7270/Q2X92B57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50280058 (CHEMBL8948 | Sodium; 9-(4-fluoro-phenyl)-3,5-dihyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against rat liver microsomal HMG-CoA reductase | Bioorg Med Chem Lett 2: 99-104 (1992) Article DOI: 10.1016/S0960-894X(00)80665-4 BindingDB Entry DOI: 10.7270/Q2X92B57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50280062 (CHEMBL8886 | Sodium; (6E,8E)-9-(4-fluoro-phenyl)-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against rat liver microsomal HMG-CoA reductase | Bioorg Med Chem Lett 2: 99-104 (1992) Article DOI: 10.1016/S0960-894X(00)80665-4 BindingDB Entry DOI: 10.7270/Q2X92B57 | |||||||||||
More data for this Ligand-Target Pair |