Found 9 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Proprotein convertase subtilisin/kexin type 9
(Homo sapiens (Human)) | BDBM50280216
(Borinic acid derivative | CHEMBL31523 | Phenyl but...)Show InChI InChI=1S/C10H15BO/c1-2-3-9-11(12)10-7-5-4-6-8-10/h4-8,12H,2-3,9H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of subtilisin |
Bioorg Med Chem Lett 4: 2417-2420 (1994)
Article DOI: 10.1016/S0960-894X(01)80401-7 BindingDB Entry DOI: 10.7270/Q23J3CXV |
More data for this Ligand-Target Pair | |
Chymotrypsinogen A
(Bos taurus (bovine)) | BDBM50280216
(Borinic acid derivative | CHEMBL31523 | Phenyl but...)Show InChI InChI=1S/C10H15BO/c1-2-3-9-11(12)10-7-5-4-6-8-10/h4-8,12H,2-3,9H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article
| 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of chymotrypsin |
Bioorg Med Chem Lett 4: 2417-2420 (1994)
Article DOI: 10.1016/S0960-894X(01)80401-7 BindingDB Entry DOI: 10.7270/Q23J3CXV |
More data for this Ligand-Target Pair | |
Chymotrypsinogen A
(Bos taurus (bovine)) | BDBM50067889
(CHEMBL81556 | Diphenyl Borinic acid)Show InChI InChI=1S/C12H11BO/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,14H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of chymotrypsin |
Bioorg Med Chem Lett 4: 2417-2420 (1994)
Article DOI: 10.1016/S0960-894X(01)80401-7 BindingDB Entry DOI: 10.7270/Q23J3CXV |
More data for this Ligand-Target Pair | |
Proprotein convertase subtilisin/kexin type 9
(Homo sapiens (Human)) | BDBM50067889
(CHEMBL81556 | Diphenyl Borinic acid)Show InChI InChI=1S/C12H11BO/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,14H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of subtilisin |
Bioorg Med Chem Lett 4: 2417-2420 (1994)
Article DOI: 10.1016/S0960-894X(01)80401-7 BindingDB Entry DOI: 10.7270/Q23J3CXV |
More data for this Ligand-Target Pair | |
Chymotrypsinogen A
(Bos taurus (bovine)) | BDBM50283476
(CHEMBL78562 | Phenyl methyl borinic acid)Show InChI InChI=1S/C7H9BO/c1-8(9)7-5-3-2-4-6-7/h2-6,9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of chymotrypsin |
Bioorg Med Chem Lett 4: 2417-2420 (1994)
Article DOI: 10.1016/S0960-894X(01)80401-7 BindingDB Entry DOI: 10.7270/Q23J3CXV |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50067889
(CHEMBL81556 | Diphenyl Borinic acid)Show InChI InChI=1S/C12H11BO/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,14H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of trypsin |
Bioorg Med Chem Lett 4: 2417-2420 (1994)
Article DOI: 10.1016/S0960-894X(01)80401-7 BindingDB Entry DOI: 10.7270/Q23J3CXV |
More data for this Ligand-Target Pair | |
Proprotein convertase subtilisin/kexin type 9
(Homo sapiens (Human)) | BDBM26996
(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article
| 4.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of subtilisin |
Bioorg Med Chem Lett 4: 2417-2420 (1994)
Article DOI: 10.1016/S0960-894X(01)80401-7 BindingDB Entry DOI: 10.7270/Q23J3CXV |
More data for this Ligand-Target Pair | |
Chymotrypsinogen A
(Bos taurus (bovine)) | BDBM26996
(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article
| 6.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of chymotrypsin |
Bioorg Med Chem Lett 4: 2417-2420 (1994)
Article DOI: 10.1016/S0960-894X(01)80401-7 BindingDB Entry DOI: 10.7270/Q23J3CXV |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM26996
(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article
| 1.02E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for the inhibition of trypsin |
Bioorg Med Chem Lett 4: 2417-2420 (1994)
Article DOI: 10.1016/S0960-894X(01)80401-7 BindingDB Entry DOI: 10.7270/Q23J3CXV |
More data for this Ligand-Target Pair | |