Affinity Data by BDB articleid=50029491

Articleid 50029491

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50284961 ((S)-2,8-Dimethyl-1-oxa-8-aza-spiro[4.5]decan-3-one...) Show SMILES C[C@@H]1OC2(CC1=O)CCN(C)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M2, using [3H]- N-methyl-scopolamine, a radioligand displacement as...				Bioorg Med Chem Lett 5: 1813-1818 (1995) Article DOI: 10.1016/0960-894X(95)00301-9 BindingDB Entry DOI: 10.7270/Q27M07WJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50008072 ((+)-pilocarpine \| (3S,4R)-3-ethyl-4-[(1-methyl-1H-...) Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M1, using [3H]- pirenzepine, a radioligand displacement assay in ra...				Bioorg Med Chem Lett 5: 1813-1818 (1995) Article DOI: 10.1016/0960-894X(95)00301-9 BindingDB Entry DOI: 10.7270/Q27M07WJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50034651 (2,8-Dimethyl-1-oxa-8-aza-spiro[4.5]decan-3-one \| C...) Show SMILES CC1OC2(CC1=O)CCN(C)CC2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M1, using [3H]- pirenzepine, a radioligand displacement assay in ra...				Bioorg Med Chem Lett 5: 1813-1818 (1995) Article DOI: 10.1016/0960-894X(95)00301-9 BindingDB Entry DOI: 10.7270/Q27M07WJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50284961 ((S)-2,8-Dimethyl-1-oxa-8-aza-spiro[4.5]decan-3-one...) Show SMILES C[C@@H]1OC2(CC1=O)CCN(C)CC2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M1, using [3H]- pirenzepine, a radioligand displacement assay in ra...				Bioorg Med Chem Lett 5: 1813-1818 (1995) Article DOI: 10.1016/0960-894X(95)00301-9 BindingDB Entry DOI: 10.7270/Q27M07WJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50034651 (2,8-Dimethyl-1-oxa-8-aza-spiro[4.5]decan-3-one \| C...) Show SMILES CC1OC2(CC1=O)CCN(C)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M2, using [3H]- N-methyl-scopolamine, a radioligand displacement as...				Bioorg Med Chem Lett 5: 1813-1818 (1995) Article DOI: 10.1016/0960-894X(95)00301-9 BindingDB Entry DOI: 10.7270/Q27M07WJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50008072 ((+)-pilocarpine \| (3S,4R)-3-ethyl-4-[(1-methyl-1H-...) Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M2, using [3H]- N-methyl-scopolamine, a radioligand displacement as...				Bioorg Med Chem Lett 5: 1813-1818 (1995) Article DOI: 10.1016/0960-894X(95)00301-9 BindingDB Entry DOI: 10.7270/Q27M07WJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50284962 ((R)-2,8-Dimethyl-1-oxa-8-aza-spiro[4.5]decan-3-one...) Show SMILES C[C@H]1OC2(CC1=O)CCN(C)CC2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M1, using [3H]- pirenzepine, a radioligand displacement assay in ra...				Bioorg Med Chem Lett 5: 1813-1818 (1995) Article DOI: 10.1016/0960-894X(95)00301-9 BindingDB Entry DOI: 10.7270/Q27M07WJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50284962 ((R)-2,8-Dimethyl-1-oxa-8-aza-spiro[4.5]decan-3-one...) Show SMILES C[C@H]1OC2(CC1=O)CCN(C)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M2, using [3H]- N-methyl-scopolamine, a radioligand displacement as...				Bioorg Med Chem Lett 5: 1813-1818 (1995) Article DOI: 10.1016/0960-894X(95)00301-9 BindingDB Entry DOI: 10.7270/Q27M07WJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%