Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50051456 (CHEMBL306344 | N-(2,6-Diisopropyl-phenyl)-2-(2-dod...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a | |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero... | Bioorg Med Chem Lett 5: 295-300 (1995) BindingDB Entry DOI: 10.7270/Q29Z94WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50051460 (2-(2-Dodecyl-2H-tetrazol-5-yl)-2-phenyl-N-(2,4,6-t...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a | |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero... | Bioorg Med Chem Lett 5: 295-300 (1995) BindingDB Entry DOI: 10.7270/Q29Z94WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50450396 (CHEMBL102912) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a | |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero... | Bioorg Med Chem Lett 5: 295-300 (1995) BindingDB Entry DOI: 10.7270/Q29Z94WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50051460 (2-(2-Dodecyl-2H-tetrazol-5-yl)-2-phenyl-N-(2,4,6-t...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a | |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero... | Bioorg Med Chem Lett 5: 295-300 (1995) BindingDB Entry DOI: 10.7270/Q29Z94WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50051460 (2-(2-Dodecyl-2H-tetrazol-5-yl)-2-phenyl-N-(2,4,6-t...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a | |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero... | Bioorg Med Chem Lett 5: 295-300 (1995) BindingDB Entry DOI: 10.7270/Q29Z94WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50450398 (CHEMBL100448) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a | |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero... | Bioorg Med Chem Lett 5: 295-300 (1995) BindingDB Entry DOI: 10.7270/Q29Z94WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50450397 (CHEMBL103748) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a | |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero... | Bioorg Med Chem Lett 5: 295-300 (1995) BindingDB Entry DOI: 10.7270/Q29Z94WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero... | Bioorg Med Chem Lett 5: 295-300 (1995) BindingDB Entry DOI: 10.7270/Q29Z94WS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sterol O-acyltransferase 1 (Rattus norvegicus) | BDBM50450395 (CHEMBL318600) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a | |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero... | Bioorg Med Chem Lett 5: 295-300 (1995) BindingDB Entry DOI: 10.7270/Q29Z94WS | |||||||||||
More data for this Ligand-Target Pair |