Found 60 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50040594
((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O Show InChI InChI=1S/C32H36N4O6/c1-19(2)15-26(29(38)35-27(28(37)33-3)16-20-9-5-4-6-10-20)34-25(32(41)42)13-14-36-30(39)23-17-21-11-7-8-12-22(21)18-24(23)31(36)40/h4-12,17-19,25-27,34H,13-16H2,1-3H3,(H,33,37)(H,35,38)(H,41,42)/t25-,26+,27+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1 |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288702
((R)-6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[(S)...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCN1C(=O)c2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H42N4O6/c1-24(2)23-31(33(42)37-26-15-7-4-8-16-26)39-32(41)29(21-20-25-13-5-3-6-14-25)38-30(36(45)46)19-11-12-22-40-34(43)27-17-9-10-18-28(27)35(40)44/h3-10,13-18,24,29-31,38H,11-12,19-23H2,1-2H3,(H,37,42)(H,39,41)(H,45,46)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288710
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCNC(=O)CCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)25-32(35(43)38-29-17-10-5-11-18-29)40-34(42)30(22-20-27-13-6-3-7-14-27)39-31(36(44)45)19-12-24-37-33(41)23-21-28-15-8-4-9-16-28/h3-11,13-18,26,30-32,39H,12,19-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288705
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H44N4O5/c1-25(2)23-31(34(42)37-28-17-10-5-11-18-28)39-33(41)29(21-20-26-13-6-3-7-14-26)38-30(35(43)44)19-12-22-36-32(40)24-27-15-8-4-9-16-27/h3-11,13-18,25,29-31,38H,12,19-24H2,1-2H3,(H,36,40)(H,37,42)(H,39,41)(H,43,44)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288708
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCN1Cc2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H44N4O5/c1-25(2)23-32(34(42)37-28-16-7-4-8-17-28)39-33(41)30(21-20-26-13-5-3-6-14-26)38-31(36(44)45)19-11-12-22-40-24-27-15-9-10-18-29(27)35(40)43/h3-10,13-18,25,30-32,38H,11-12,19-24H2,1-2H3,(H,37,42)(H,39,41)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50040594
((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O Show InChI InChI=1S/C32H36N4O6/c1-19(2)15-26(29(38)35-27(28(37)33-3)16-20-9-5-4-6-10-20)34-25(32(41)42)13-14-36-30(39)23-17-21-11-7-8-12-22(21)18-24(23)31(36)40/h4-12,17-19,25-27,34H,13-16H2,1-3H3,(H,33,37)(H,35,38)(H,41,42)/t25-,26+,27+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -3 |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288704
((R)-7-Benzoylamino-2-[(S)-1-((S)-3-methyl-1-phenyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCCNC(=O)c1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)25-32(35(43)38-29-19-11-5-12-20-29)40-34(42)30(23-22-27-15-7-3-8-16-27)39-31(36(44)45)21-13-6-14-24-37-33(41)28-17-9-4-10-18-28/h3-5,7-12,15-20,26,30-32,39H,6,13-14,21-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288716
((R)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[(S)...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C34H38N4O6/c1-22(2)21-29(31(40)35-24-13-7-4-8-14-24)37-30(39)27(18-17-23-11-5-3-6-12-23)36-28(34(43)44)19-20-38-32(41)25-15-9-10-16-26(25)33(38)42/h3-16,22,27-29,36H,17-21H2,1-2H3,(H,35,40)(H,37,39)(H,43,44)/t27-,28+,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288707
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)24-32(35(43)38-29-18-10-5-11-19-29)40-34(42)30(22-21-27-14-6-3-7-15-27)39-31(36(44)45)20-12-13-23-37-33(41)25-28-16-8-4-9-17-28/h3-11,14-19,26,30-32,39H,12-13,20-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288720
((R)-6-Benzoylamino-2-[(S)-1-((S)-3-methyl-1-phenyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)c1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H44N4O5/c1-25(2)24-31(34(42)37-28-18-10-5-11-19-28)39-33(41)29(22-21-26-14-6-3-7-15-26)38-30(35(43)44)20-12-13-23-36-32(40)27-16-8-4-9-17-27/h3-11,14-19,25,29-31,38H,12-13,20-24H2,1-2H3,(H,36,40)(H,37,42)(H,39,41)(H,43,44)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288716
((R)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[(S)...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C34H38N4O6/c1-22(2)21-29(31(40)35-24-13-7-4-8-14-24)37-30(39)27(18-17-23-11-5-3-6-12-23)36-28(34(43)44)19-20-38-32(41)25-15-9-10-16-26(25)33(38)42/h3-16,22,27-29,36H,17-21H2,1-2H3,(H,35,40)(H,37,39)(H,43,44)/t27-,28+,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288717
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C37H48N4O5/c1-27(2)25-33(36(44)39-30-19-11-5-12-20-30)41-35(43)31(23-22-28-15-7-3-8-16-28)40-32(37(45)46)21-13-6-14-24-38-34(42)26-29-17-9-4-10-18-29/h3-5,7-12,15-20,27,31-33,40H,6,13-14,21-26H2,1-2H3,(H,38,42)(H,39,44)(H,41,43)(H,45,46)/t31-,32+,33-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288705
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H44N4O5/c1-25(2)23-31(34(42)37-28-17-10-5-11-18-28)39-33(41)29(21-20-26-13-6-3-7-14-26)38-30(35(43)44)19-12-22-36-32(40)24-27-15-8-4-9-16-27/h3-11,13-18,25,29-31,38H,12,19-24H2,1-2H3,(H,36,40)(H,37,42)(H,39,41)(H,43,44)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288707
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)24-32(35(43)38-29-18-10-5-11-19-29)40-34(42)30(22-21-27-14-6-3-7-15-27)39-31(36(44)45)20-12-13-23-37-33(41)25-28-16-8-4-9-17-28/h3-11,14-19,26,30-32,39H,12-13,20-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288715
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C34H43N3O4/c1-25(2)24-31(33(39)35-28-19-10-5-11-20-28)37-32(38)29(23-22-27-16-8-4-9-17-27)36-30(34(40)41)21-13-12-18-26-14-6-3-7-15-26/h3-11,14-17,19-20,25,29-31,36H,12-13,18,21-24H2,1-2H3,(H,35,39)(H,37,38)(H,40,41)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288702
((R)-6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[(S)...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCN1C(=O)c2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H42N4O6/c1-24(2)23-31(33(42)37-26-15-7-4-8-16-26)39-32(41)29(21-20-25-13-5-3-6-14-25)38-30(36(45)46)19-11-12-22-40-34(43)27-17-9-10-18-28(27)35(40)44/h3-10,13-18,24,29-31,38H,11-12,19-23H2,1-2H3,(H,37,42)(H,39,41)(H,45,46)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50040594
((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O Show InChI InChI=1S/C32H36N4O6/c1-19(2)15-26(29(38)35-27(28(37)33-3)16-20-9-5-4-6-10-20)34-25(32(41)42)13-14-36-30(39)23-17-21-11-7-8-12-22(21)18-24(23)31(36)40/h4-12,17-19,25-27,34H,13-16H2,1-3H3,(H,33,37)(H,35,38)(H,41,42)/t25-,26+,27+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase-2 |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288700
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCNC(=O)CCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H44N4O5/c1-25(2)24-31(34(42)37-28-16-10-5-11-17-28)39-33(41)29(20-18-26-12-6-3-7-13-26)38-30(35(43)44)22-23-36-32(40)21-19-27-14-8-4-9-15-27/h3-17,25,29-31,38H,18-24H2,1-2H3,(H,36,40)(H,37,42)(H,39,41)(H,43,44)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288708
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCN1Cc2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H44N4O5/c1-25(2)23-32(34(42)37-28-16-7-4-8-17-28)39-33(41)30(21-20-26-13-5-3-6-14-26)38-31(36(44)45)19-11-12-22-40-24-27-15-9-10-18-29(27)35(40)43/h3-10,13-18,25,30-32,38H,11-12,19-24H2,1-2H3,(H,37,42)(H,39,41)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288703
((R)-4-Benzoylamino-2-[(S)-1-((S)-3-methyl-1-phenyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCNC(=O)c1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C33H40N4O5/c1-23(2)22-29(32(40)35-26-16-10-5-11-17-26)37-31(39)27(19-18-24-12-6-3-7-13-24)36-28(33(41)42)20-21-34-30(38)25-14-8-4-9-15-25/h3-17,23,27-29,36H,18-22H2,1-2H3,(H,34,38)(H,35,40)(H,37,39)(H,41,42)/t27-,28+,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288720
((R)-6-Benzoylamino-2-[(S)-1-((S)-3-methyl-1-phenyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)c1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H44N4O5/c1-25(2)24-31(34(42)37-28-18-10-5-11-19-28)39-33(41)29(22-21-26-14-6-3-7-15-26)38-30(35(43)44)20-12-13-23-36-32(40)27-16-8-4-9-17-27/h3-11,14-19,25,29-31,38H,12-13,20-24H2,1-2H3,(H,36,40)(H,37,42)(H,39,41)(H,43,44)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288704
((R)-7-Benzoylamino-2-[(S)-1-((S)-3-methyl-1-phenyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCCNC(=O)c1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)25-32(35(43)38-29-19-11-5-12-20-29)40-34(42)30(23-22-27-15-7-3-8-16-27)39-31(36(44)45)21-13-6-14-24-37-33(41)28-17-9-4-10-18-28/h3-5,7-12,15-20,26,30-32,39H,6,13-14,21-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288715
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C34H43N3O4/c1-25(2)24-31(33(39)35-28-19-10-5-11-20-28)37-32(38)29(23-22-27-16-8-4-9-17-27)36-30(34(40)41)21-13-12-18-26-14-6-3-7-15-26/h3-11,14-17,19-20,25,29-31,36H,12-13,18,21-24H2,1-2H3,(H,35,39)(H,37,38)(H,40,41)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288711
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCNC(=O)CCCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C37H48N4O5/c1-27(2)26-33(36(44)39-30-19-10-5-11-20-30)41-35(43)31(24-23-29-16-8-4-9-17-29)40-32(37(45)46)21-13-25-38-34(42)22-12-18-28-14-6-3-7-15-28/h3-11,14-17,19-20,27,31-33,40H,12-13,18,21-26H2,1-2H3,(H,38,42)(H,39,44)(H,41,43)(H,45,46)/t31-,32+,33-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288713
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C34H42N4O5/c1-24(2)22-30(33(41)36-27-16-10-5-11-17-27)38-32(40)28(19-18-25-12-6-3-7-13-25)37-29(34(42)43)20-21-35-31(39)23-26-14-8-4-9-15-26/h3-17,24,28-30,37H,18-23H2,1-2H3,(H,35,39)(H,36,41)(H,38,40)(H,42,43)/t28-,29+,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288721
((R)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[(S)...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCN1C(=O)c2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H40N4O6/c1-23(2)22-30(32(41)36-25-14-7-4-8-15-25)38-31(40)28(20-19-24-12-5-3-6-13-24)37-29(35(44)45)18-11-21-39-33(42)26-16-9-10-17-27(26)34(39)43/h3-10,12-17,23,28-30,37H,11,18-22H2,1-2H3,(H,36,41)(H,38,40)(H,44,45)/t28-,29+,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288701
((R)-6-[(1-Acetyl-pyrrolidine-2-carbonyl)-amino]-2-...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)C1CCCN1C(C)=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H49N5O6/c1-24(2)23-30(33(43)37-27-15-8-5-9-16-27)39-32(42)28(20-19-26-13-6-4-7-14-26)38-29(35(45)46)17-10-11-21-36-34(44)31-18-12-22-40(31)25(3)41/h4-9,13-16,24,28-31,38H,10-12,17-23H2,1-3H3,(H,36,44)(H,37,43)(H,39,42)(H,45,46)/t28-,29+,30-,31?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288709
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)CCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C37H48N4O5/c1-27(2)26-33(36(44)39-30-18-10-5-11-19-30)41-35(43)31(23-21-28-14-6-3-7-15-28)40-32(37(45)46)20-12-13-25-38-34(42)24-22-29-16-8-4-9-17-29/h3-11,14-19,27,31-33,40H,12-13,20-26H2,1-2H3,(H,38,42)(H,39,44)(H,41,43)(H,45,46)/t31-,32+,33-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50057083
((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](C)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C25H33N3O4/c1-17(2)16-22(24(30)27-20-12-8-5-9-13-20)28-23(29)21(26-18(3)25(31)32)15-14-19-10-6-4-7-11-19/h4-13,17-18,21-22,26H,14-16H2,1-3H3,(H,27,30)(H,28,29)(H,31,32)/t18-,21+,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288718
((R)-5-Benzoylamino-2-[(S)-1-((S)-3-methyl-1-phenyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCNC(=O)c1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C34H42N4O5/c1-24(2)23-30(33(41)36-27-17-10-5-11-18-27)38-32(40)28(21-20-25-13-6-3-7-14-25)37-29(34(42)43)19-12-22-35-31(39)26-15-8-4-9-16-26/h3-11,13-18,24,28-30,37H,12,19-23H2,1-2H3,(H,35,39)(H,36,41)(H,38,40)(H,42,43)/t28-,29+,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288714
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCNC(=O)CCCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)25-32(35(43)38-29-18-10-5-11-19-29)40-34(42)30(22-21-28-15-8-4-9-16-28)39-31(36(44)45)23-24-37-33(41)20-12-17-27-13-6-3-7-14-27/h3-11,13-16,18-19,26,30-32,39H,12,17,20-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288712
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CCCC[C@@H](N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccccc1)C(O)=O Show InChI InChI=1S/C28H39N3O4/c1-4-5-16-24(28(34)35)30-23(18-17-21-12-8-6-9-13-21)26(32)31-25(19-20(2)3)27(33)29-22-14-10-7-11-15-22/h6-15,20,23-25,30H,4-5,16-19H2,1-3H3,(H,29,33)(H,31,32)(H,34,35)/t23-,24+,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288717
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C37H48N4O5/c1-27(2)25-33(36(44)39-30-19-11-5-12-20-30)41-35(43)31(23-22-28-15-7-3-8-16-28)40-32(37(45)46)21-13-6-14-24-38-34(42)26-29-17-9-4-10-18-29/h3-5,7-12,15-20,27,31-33,40H,6,13-14,21-26H2,1-2H3,(H,38,42)(H,39,44)(H,41,43)(H,45,46)/t31-,32+,33-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288706
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC[C@@H](N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccccc1)C(O)=O Show InChI InChI=1S/C26H35N3O4/c1-4-21(26(32)33)28-22(16-15-19-11-7-5-8-12-19)24(30)29-23(17-18(2)3)25(31)27-20-13-9-6-10-14-20/h5-14,18,21-23,28H,4,15-17H2,1-3H3,(H,27,31)(H,29,30)(H,32,33)/t21-,22+,23+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50057083
((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](C)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C25H33N3O4/c1-17(2)16-22(24(30)27-20-12-8-5-9-13-20)28-23(29)21(26-18(3)25(31)32)15-14-19-10-6-4-7-11-19/h4-13,17-18,21-22,26H,14-16H2,1-3H3,(H,27,30)(H,28,29)(H,31,32)/t18-,21+,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50288719
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CCCCCC[C@@H](N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccccc1)C(O)=O Show InChI InChI=1S/C30H43N3O4/c1-4-5-6-13-18-26(30(36)37)32-25(20-19-23-14-9-7-10-15-23)28(34)33-27(21-22(2)3)29(35)31-24-16-11-8-12-17-24/h7-12,14-17,22,25-27,32H,4-6,13,18-21H2,1-3H3,(H,31,35)(H,33,34)(H,36,37)/t25-,26+,27-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-3. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288721
((R)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[(S)...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCN1C(=O)c2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H40N4O6/c1-23(2)22-30(32(41)36-25-14-7-4-8-15-25)38-31(40)28(20-19-24-12-5-3-6-13-24)37-29(35(44)45)18-11-21-39-33(42)26-16-9-10-17-27(26)34(39)43/h3-10,12-17,23,28-30,37H,11,18-22H2,1-2H3,(H,36,41)(H,38,40)(H,44,45)/t28-,29+,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288702
((R)-6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[(S)...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCN1C(=O)c2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H42N4O6/c1-24(2)23-31(33(42)37-26-15-7-4-8-16-26)39-32(41)29(21-20-25-13-5-3-6-14-25)38-30(36(45)46)19-11-12-22-40-34(43)27-17-9-10-18-28(27)35(40)44/h3-10,13-18,24,29-31,38H,11-12,19-23H2,1-2H3,(H,37,42)(H,39,41)(H,45,46)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50057083
((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](C)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C25H33N3O4/c1-17(2)16-22(24(30)27-20-12-8-5-9-13-20)28-23(29)21(26-18(3)25(31)32)15-14-19-10-6-4-7-11-19/h4-13,17-18,21-22,26H,14-16H2,1-3H3,(H,27,30)(H,28,29)(H,31,32)/t18-,21+,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288714
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCNC(=O)CCCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)25-32(35(43)38-29-18-10-5-11-19-29)40-34(42)30(22-21-28-15-8-4-9-16-28)39-31(36(44)45)23-24-37-33(41)20-12-17-27-13-6-3-7-14-27/h3-11,13-16,18-19,26,30-32,39H,12,17,20-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 770 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288705
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H44N4O5/c1-25(2)23-31(34(42)37-28-17-10-5-11-18-28)39-33(41)29(21-20-26-13-6-3-7-14-26)38-30(35(43)44)19-12-22-36-32(40)24-27-15-8-4-9-16-27/h3-11,13-18,25,29-31,38H,12,19-24H2,1-2H3,(H,36,40)(H,37,42)(H,39,41)(H,43,44)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288703
((R)-4-Benzoylamino-2-[(S)-1-((S)-3-methyl-1-phenyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCNC(=O)c1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C33H40N4O5/c1-23(2)22-29(32(40)35-26-16-10-5-11-17-26)37-31(39)27(19-18-24-12-6-3-7-13-24)36-28(33(41)42)20-21-34-30(38)25-14-8-4-9-15-25/h3-17,23,27-29,36H,18-22H2,1-2H3,(H,34,38)(H,35,40)(H,37,39)(H,41,42)/t27-,28+,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288712
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CCCC[C@@H](N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccccc1)C(O)=O Show InChI InChI=1S/C28H39N3O4/c1-4-5-16-24(28(34)35)30-23(18-17-21-12-8-6-9-13-21)26(32)31-25(19-20(2)3)27(33)29-22-14-10-7-11-15-22/h6-15,20,23-25,30H,4-5,16-19H2,1-3H3,(H,29,33)(H,31,32)(H,34,35)/t23-,24+,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288706
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC[C@@H](N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccccc1)C(O)=O Show InChI InChI=1S/C26H35N3O4/c1-4-21(26(32)33)28-22(16-15-19-11-7-5-8-12-19)24(30)29-23(17-18(2)3)25(31)27-20-13-9-6-10-14-20/h5-14,18,21-23,28H,4,15-17H2,1-3H3,(H,27,31)(H,29,30)(H,32,33)/t21-,22+,23+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288701
((R)-6-[(1-Acetyl-pyrrolidine-2-carbonyl)-amino]-2-...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)C1CCCN1C(C)=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H49N5O6/c1-24(2)23-30(33(43)37-27-15-8-5-9-16-27)39-32(42)28(20-19-26-13-6-4-7-14-26)38-29(35(45)46)17-10-11-21-36-34(44)31-18-12-22-40(31)25(3)41/h4-9,13-16,24,28-31,38H,10-12,17-23H2,1-3H3,(H,36,44)(H,37,43)(H,39,42)(H,45,46)/t28-,29+,30-,31?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288708
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCN1Cc2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H44N4O5/c1-25(2)23-32(34(42)37-28-16-7-4-8-17-28)39-33(41)30(21-20-26-13-5-3-6-14-26)38-31(36(44)45)19-11-12-22-40-24-27-15-9-10-18-29(27)35(40)43/h3-10,13-18,25,30-32,38H,11-12,19-24H2,1-2H3,(H,37,42)(H,39,41)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288713
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C34H42N4O5/c1-24(2)22-30(33(41)36-27-16-10-5-11-17-27)38-32(40)28(19-18-25-12-6-3-7-13-25)37-29(34(42)43)20-21-35-31(39)23-26-14-8-4-9-15-26/h3-17,24,28-30,37H,18-23H2,1-2H3,(H,35,39)(H,36,41)(H,38,40)(H,42,43)/t28-,29+,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288706
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC[C@@H](N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccccc1)C(O)=O Show InChI InChI=1S/C26H35N3O4/c1-4-21(26(32)33)28-22(16-15-19-11-7-5-8-12-19)24(30)29-23(17-18(2)3)25(31)27-20-13-9-6-10-14-20/h5-14,18,21-23,28H,4,15-17H2,1-3H3,(H,27,31)(H,29,30)(H,32,33)/t21-,22+,23+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288716
((R)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[(S)...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C34H38N4O6/c1-22(2)21-29(31(40)35-24-13-7-4-8-14-24)37-30(39)27(18-17-23-11-5-3-6-12-23)36-28(34(43)44)19-20-38-32(41)25-15-9-10-16-26(25)33(38)42/h3-16,22,27-29,36H,17-21H2,1-2H3,(H,35,40)(H,37,39)(H,43,44)/t27-,28+,29-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 2.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288710
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCNC(=O)CCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)25-32(35(43)38-29-17-10-5-11-18-29)40-34(42)30(22-20-27-13-6-3-7-14-27)39-31(36(44)45)19-12-24-37-33(41)23-21-28-15-8-4-9-16-28/h3-11,13-18,26,30-32,39H,12,19-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50288719
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CCCCCC[C@@H](N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccccc1)C(O)=O Show InChI InChI=1S/C30H43N3O4/c1-4-5-6-13-18-26(30(36)37)32-25(20-19-23-14-9-7-10-15-23)28(34)33-27(21-22(2)3)29(35)31-24-16-11-8-12-17-24/h7-12,14-17,22,25-27,32H,4-6,13,18-21H2,1-3H3,(H,31,35)(H,33,34)(H,36,37)/t25-,26+,27-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of MMP-2. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288700
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCNC(=O)CCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H44N4O5/c1-25(2)24-31(34(42)37-28-16-10-5-11-17-28)39-33(41)29(20-18-26-12-6-3-7-13-26)38-30(35(43)44)22-23-36-32(40)21-19-27-14-8-4-9-15-27/h3-17,25,29-31,38H,18-24H2,1-2H3,(H,36,40)(H,37,42)(H,39,41)(H,43,44)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288721
((R)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-[(S)...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCN1C(=O)c2ccccc2C1=O)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H40N4O6/c1-23(2)22-30(32(41)36-25-14-7-4-8-15-25)38-31(40)28(20-19-24-12-5-3-6-13-24)37-29(35(44)45)18-11-21-39-33(42)26-16-9-10-17-27(26)34(39)43/h3-10,12-17,23,28-30,37H,11,18-22H2,1-2H3,(H,36,41)(H,38,40)(H,44,45)/t28-,29+,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288704
((R)-7-Benzoylamino-2-[(S)-1-((S)-3-methyl-1-phenyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCCNC(=O)c1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)25-32(35(43)38-29-19-11-5-12-20-29)40-34(42)30(23-22-27-15-7-3-8-16-27)39-31(36(44)45)21-13-6-14-24-37-33(41)28-17-9-4-10-18-28/h3-5,7-12,15-20,26,30-32,39H,6,13-14,21-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 3.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288714
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCNC(=O)CCCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)25-32(35(43)38-29-18-10-5-11-19-29)40-34(42)30(22-21-28-15-8-4-9-16-28)39-31(36(44)45)23-24-37-33(41)20-12-17-27-13-6-3-7-14-27/h3-11,13-16,18-19,26,30-32,39H,12,17,20-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 4.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288720
((R)-6-Benzoylamino-2-[(S)-1-((S)-3-methyl-1-phenyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)c1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C35H44N4O5/c1-25(2)24-31(34(42)37-28-18-10-5-11-19-28)39-33(41)29(22-21-26-14-6-3-7-15-26)38-30(35(43)44)20-12-13-23-36-32(40)27-16-8-4-9-17-27/h3-11,14-19,25,29-31,38H,12-13,20-24H2,1-2H3,(H,36,40)(H,37,42)(H,39,41)(H,43,44)/t29-,30+,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288717
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C37H48N4O5/c1-27(2)25-33(36(44)39-30-19-11-5-12-20-30)41-35(43)31(23-22-28-15-7-3-8-16-28)40-32(37(45)46)21-13-6-14-24-38-34(42)26-29-17-9-4-10-18-29/h3-5,7-12,15-20,27,31-33,40H,6,13-14,21-26H2,1-2H3,(H,38,42)(H,39,44)(H,41,43)(H,45,46)/t31-,32+,33-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 5.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288712
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CCCC[C@@H](N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccccc1)C(O)=O Show InChI InChI=1S/C28H39N3O4/c1-4-5-16-24(28(34)35)30-23(18-17-21-12-8-6-9-13-21)26(32)31-25(19-20(2)3)27(33)29-22-14-10-7-11-15-22/h6-15,20,23-25,30H,4-5,16-19H2,1-3H3,(H,29,33)(H,31,32)(H,34,35)/t23-,24+,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288707
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)Cc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C36H46N4O5/c1-26(2)24-32(35(43)38-29-18-10-5-11-19-29)40-34(42)30(22-21-27-14-6-3-7-15-27)39-31(36(44)45)20-12-13-23-37-33(41)25-28-16-8-4-9-17-28/h3-11,14-19,26,30-32,39H,12-13,20-25H2,1-2H3,(H,37,41)(H,38,43)(H,40,42)(H,44,45)/t30-,31+,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50288709
((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)N[C@H](CCCCNC(=O)CCc1ccccc1)C(O)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C37H48N4O5/c1-27(2)26-33(36(44)39-30-18-10-5-11-19-30)41-35(43)31(23-21-28-14-6-3-7-15-28)40-32(37(45)46)20-12-13-25-38-34(42)24-22-29-16-8-4-9-17-29/h3-11,14-19,27,31-33,40H,12-13,20-26H2,1-2H3,(H,38,42)(H,39,44)(H,41,43)(H,45,46)/t31-,32+,33-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of matrix metalloproteinase -1. |
Bioorg Med Chem Lett 6: 329-332 (1996)
Article DOI: 10.1016/0960-894X(96)00024-8
BindingDB Entry DOI: 10.7270/Q2S75GBB |
More data for this
Ligand-Target Pair | |
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