Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Rattus norvegicus) | BDBM50289143 ((5R,10R,14S)-17-(2-Hydroxy-1-methyl-ethyl)-10-meth...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Apparent inhibitory activity of the compound was determined against rat prostatic Steroid 5-alpha-reductase type I | Bioorg Med Chem Lett 6: 883-884 (1996) Article DOI: 10.1016/0960-894X(96)00136-9 BindingDB Entry DOI: 10.7270/Q24B319W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM50403612 (CHEMBL167774) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Apparent inhibitory activity against human Steroid 5-alpha-reductase type I expressed in CHO cells | Bioorg Med Chem Lett 6: 883-884 (1996) Article DOI: 10.1016/0960-894X(96)00136-9 BindingDB Entry DOI: 10.7270/Q24B319W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Homo sapiens (Human)) | BDBM50403612 (CHEMBL167774) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Apparent inhibitory activity against human Steroid 5-alpha-reductase type 2 expressed in CHO cells | Bioorg Med Chem Lett 6: 883-884 (1996) Article DOI: 10.1016/0960-894X(96)00136-9 BindingDB Entry DOI: 10.7270/Q24B319W | |||||||||||
More data for this Ligand-Target Pair |