Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calpain-1 catalytic subunit (Homo sapiens (Human)) | BDBM50073850 ((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Homo sapiens (Human)) | BDBM50287391 ((R)-4-Methyl-2-[2-oxo-2-(9H-xanthen-9-yl)-ethyl]-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Homo sapiens (Human)) | BDBM50290965 ((R)-4-Methyl-2-[2-(naphthalene-2-sulfinyl)-ethyl]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Homo sapiens (Human)) | BDBM50290966 ((R)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50290963 ((R)-4-Methyl-2-[2-(naphthalen-2-ylsulfanyl)-ethyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50290965 ((R)-4-Methyl-2-[2-(naphthalene-2-sulfinyl)-ethyl]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Homo sapiens (Human)) | BDBM50290963 ((R)-4-Methyl-2-[2-(naphthalen-2-ylsulfanyl)-ethyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50290966 ((R)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Homo sapiens (Human)) | BDBM50290964 ((S)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50290964 ((S)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was determined using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate. | Bioorg Med Chem Lett 7: 287-290 (1997) Article DOI: 10.1016/S0960-894X(97)00003-6 BindingDB Entry DOI: 10.7270/Q2KS6RJC | |||||||||||
More data for this Ligand-Target Pair |