Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283917 (1-(1,1-Diphenyl-silolan-3-yl)-4-(4-fluoro-phenyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283931 (1-(1,1-Diphenyl-silolan-3-yl)-4-phenyl-piperazine ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50001775 ((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283920 (1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283920 (1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283928 (1-(1,1-Diphenyl-silolan-3-yl)-4-(3-fluoro-phenyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283929 (1-(1,1-Diphenyl-silolan-3-yl)-4-p-tolyl-piperazine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283921 (1-(1,1-Diphenyl-silolan-3-yl)-4-(4-fluoro-phenyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283919 (1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-(4-fl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283924 (1-(4-Chloro-phenyl)-4-(1,1-diphenyl-silolan-3-yl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283918 (1-[1-(4-Fluoro-phenyl)-1-phenyl-silolan-3-yl]-4-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283918 (1-[1-(4-Fluoro-phenyl)-1-phenyl-silolan-3-yl]-4-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283923 (1-(1,1-Diphenyl-silolan-3-yl)-4-pyridin-2-yl-piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283926 (1-(1,1-Diphenyl-silolan-3-yl)-4-m-tolyl-piperazine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283925 (4-[4-(1,1-Diphenyl-silolan-3-yl)-piperazin-1-yl]-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283927 (1-(1,1-Diphenyl-silolan-3-yl)-4-phenyl-piperidine ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283930 (2-[4-(1,1-Diphenyl-silolan-3-yl)-piperazin-1-yl]-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50283920 (1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards dopamine D2 receptor | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50283920 (1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards dopamine D2 receptor | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50283932 (1-(1,1-Diphenyl-silolan-3-yl)-4-(2-fluoro-phenyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM50283920 (1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards histamine H1 receptor | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50283920 (1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards muscarinic receptor | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM50283920 (1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards histamine H1 receptor | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50283920 (1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards muscarinic receptor | Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M | |||||||||||
More data for this Ligand-Target Pair |